Allosteric Modulators of GABA(B) Receptors: Mechanism of Action and Therapeutic Perspective

por Pin, Jean-Philippe, Prézeau, Laurent
Publicado 2007

Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer

por Ayoub, Mohammed Akli, Pin, Jean-Philippe
Publicado 2013

Receptor-G Protein Interaction Studied by Bioluminescence Resonance Energy Transfer: Lessons from Protease-Activated Receptor 1

por Ayoub, Mohammed Akli, Al-Senaidy, Abdulrahman, Pin, Jean-Philippe
Publicado 2012

Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand

por Dalton, James A. R., Pin, Jean-Philippe, Giraldo, Jesús
Publicado 2017

Complex GABA(B) receptor complexes: how to generate multiple functionally distinct units from a single receptor

por Xu, Chanjuan, Zhang, Wenhua, Rondard, Philippe, Pin, Jean-Philippe, Liu, Jianfeng
Publicado 2014

Class C G protein-coupled receptors: reviving old couples with new partners

por Møller, Thor C., Moreno-Delgado, David, Pin, Jean-Philippe, Kniazeff, Julie
Publicado 2017

Targeting the Brain with Single-Domain Antibodies: Greater Potential Than Stated So Far?

por Tsitokana, Mireille Elodie, Lafon, Pierre-André, Prézeau, Laurent, Pin, Jean-Philippe, Rondard, Philippe
Publicado 2023

Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening

por Cottet, Martin, Faklaris, Orestis, Zwier, Jurriaan M., Trinquet, Eric, Pin, Jean-Philippe, Durroux, Thierry
Publicado 2011

Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state

por Cao, Anne-Marinette, Quast, Robert B., Fatemi, Fataneh, Rondard, Philippe, Pin, Jean-Philippe, Margeat, Emmanuel
Publicado 2021

BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues

por Cottet, Martin, Faklaris, Orestis, Maurel, Damien, Scholler, Pauline, Doumazane, Etienne, Trinquet, Eric, Pin, Jean-Philippe, Durroux, Thierry
Publicado 2012

SGIP1 modulates kinetics and interactions of the cannabinoid receptor 1 and G protein‐coupled receptor kinase 3 signalosome

por Gazdarica, Matej, Noda, Judith, Durydivka, Oleh, Novosadova, Vendula, Mackie, Ken, Pin, Jean‐Philippe, Prezeau, Laurent, Blahos, Jaroslav
Publicado 2022

Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer

por Xue, Li, Sun, Qian, Zhao, Han, Rovira, Xavier, Gai, Siyu, He, Qianwen, Pin, Jean-Philippe, Liu, Jianfeng, Rondard, Philippe
Publicado 2019

Investigation of Prolactin Receptor Activation and Blockade Using Time-Resolved Fluorescence Resonance Energy Transfer

por Tallet, Estelle, Fernandez, Isabelle, Zhang, Chi, Salsac, Marion, Gregor, Nathalie, Ayoub, Mohammed Akli, Pin, Jean Philippe, Trinquet, Eric, Goffin, Vincent
Publicado 2011

Direct coupling of detergent purified human mGlu(5) receptor to the heterotrimeric G proteins Gq and Gs

por Nasrallah, Chady, Rottier, Karine, Marcellin, Romain, Compan, Vincent, Font, Joan, Llebaria, Amadeu, Pin, Jean-Philippe, Banères, Jean-Louis, Lebon, Guillaume
Publicado 2018

Allosteric ligands control the activation of a class C GPCR heterodimer by acting at the transmembrane interface

por Liu, Lei, Fan, Zhiran, Rovira, Xavier, Xue, Li, Roux, Salomé, Brabet, Isabelle, Xin, Mingxia, Pin, Jean-Philippe, Rondard, Philippe, Liu, Jianfeng
Publicado 2021

A New Family of Receptor Tyrosine Kinases with a Venus Flytrap Binding Domain in Insects and Other Invertebrates Activated by Aminoacids

por Ahier, Arnaud, Rondard, Philippe, Gouignard, Nadège, Khayath, Naji, Huang, Siluo, Trolet, Jacques, Donoghue, Daniel J., Gauthier, Monique, Pin, Jean-Philippe, Dissous, Colette
Publicado 2009

Identification of key phosphorylation sites in PTH1R that determine arrestin3 binding and fine-tune receptor signaling

por Zindel, Diana, Engel, Sandra, Bottrill, Andrew R., Pin, Jean-Philippe, Prézeau, Laurent, Tobin, Andrew B., Bünemann, Moritz, Krasel, Cornelius, Butcher, Adrian J.
Publicado 2016

RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia

por Christensen, Sean B., Hone, Arik J., Roux, Isabelle, Kniazeff, Julie, Pin, Jean-Philippe, Upert, Grégory, Servent, Denis, Glowatzki, Elisabeth, McIntosh, J. Michael
Publicado 2017

Structural basis of the activation of a metabotropic GABA receptor

por Shaye, Hamidreza, Ishchenko, Andrii, Lam, Jordy Homing, Han, Gye Won, Xue, Li, Rondard, Philippe, Pin, Jean-Philippe, Katritch, Vsevolod, Gati, Cornelius, Cherezov, Vadim
Publicado 2020

Up-regulation of GABA(B) Receptor Signaling by Constitutive Assembly with the K(+) Channel Tetramerization Domain-containing Protein 12 (KCTD12)

por Ivankova, Klara, Turecek, Rostislav, Fritzius, Thorsten, Seddik, Riad, Prezeau, Laurent, Comps-Agrar, Laëtitia, Pin, Jean-Philippe, Fakler, Bernd, Besseyrias, Valerie, Gassmann, Martin, Bettler, Bernhard
Publicado 2013