Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics

por Piper, Peter W., Millson, Stefan H.
Publicado 2012

Mechanisms of Resistance to Hsp90 Inhibitor Drugs: A Complex Mosaic Emerges

por Piper, Peter W., Millson, Stefan H.
Publicado 2011

Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor (Hsf1) can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibi...

por Millson, Stefan H., Piper, Peter W.
Publicado 2014

Mutation of the Ser18 phosphorylation site on the sole Saccharomyces cerevisiae UCS protein, She4, can compromise high-temperature survival

por Gomez-Escalante, Susana, Piper, Peter W., Millson, Stefan H.
Publicado 2016

Hsp90 and phosphorylation of the Slt2(Mpk1) MAP kinase activation loop are essential for catalytic, but not non-catalytic, Slt2-mediated transcription in yeast

por Millson, Stefan H., Truman, Andrew W., Piper, Peter W.
Publicado 2022

A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s

por Vaughan, Cara K, Piper, Peter W, Pearl, Laurence H, Prodromou, Chrisostomos
Publicado 2009

UCS protein function is partially restored in the Saccharomyces cerevisiae she4 mutant with expression of the human UNC45-GC, but not UNC45-SM

por Escalante, Susana Gómez, Brightmore, Joseph A., Piper, Peter W., Millson, Stefan H.
Publicado 2017

Chaperone ligand-discrimination by the TPR-domain protein Tah1

por Millson, Stefan H., Vaughan, Cara K., Zhai, Chao, Ali, Maruf M. U., Panaretou, Barry, Piper, Peter W., Pearl, Laurence H., Prodromou, Chrisostomos
Publicado 2008

Hsp90-Dependent Activation of Protein Kinases Is Regulated by Chaperone-Targeted Dephosphorylation of Cdc37

por Vaughan, Cara K., Mollapour, Mehdi, Smith, Jennifer R., Truman, Andrew, Hu, Bin, Good, Valerie M., Panaretou, Barry, Neckers, Len, Clarke, Paul A., Workman, Paul, Piper, Peter W., Prodromou, Chrisostomos, Pearl, Laurence H.
Publicado 2008