Aldehyde accumulation in Mycobacterium tuberculosis with defective proteasomal degradation results in copper sensitivity

por Limón, Gina, Samhadaneh, Nora M., Pironti, Alejandro, Darwin, K. Heran
Publicado 2023

Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences

por Pironti, Alejandro, Pfeifer, Nico, Kaiser, Rolf, Walter, Hauke, Lengauer, Thomas
Publicado 2014

Using drug exposure for predicting drug resistance – A data-driven genotypic interpretation tool

por Pironti, Alejandro, Pfeifer, Nico, Walter, Hauke, Jensen, Björn-Erik O., Zazzi, Maurizio, Gomes, Perpétua, Kaiser, Rolf, Lengauer, Thomas
Publicado 2017

Determination of Phenotypic Resistance Cutoffs From Routine Clinical Data

por Pironti, Alejandro, Walter, Hauke, Pfeifer, Nico, Knops, Elena, Lübke, Nadine, Büch, Joachim, Di Giambenedetto, Simona, Kaiser, Rolf, Lengauer, Thomas
Publicado 2017

Microbiome-Independent Effects of Antibiotics in a Murine Model of Nosocomial Infections

por Lacey, Keenan A., Gonzalez, Sandra, Yeung, Frank, Putzel, Gregory, Podkowik, Magdalena, Pironti, Alejandro, Shopsin, Bo, Cadwell, Ken, Torres, Victor J.
Publicado 2022

1202. Multimodal Sequencing of a Clonal Case Cluster of Carbapenem-Resistant Citrobacter Reveals Unexpectedly Rapid Dynamics of KPC3-Containing Plasmids

por Bhattacharyya, Roby, Pironti, Alejandro, Walker, Bruce J, Manson, Abigail, Pierce, Virginia, Ferraro, Mary Jane, Shenoy, Erica, Hooper, David C, Earl, Ashlee
Publicado 2018

Effects of Capsular Polysaccharide amount on Pneumococcal-Host interactions

por Zhu, Jiaqi, Abruzzo, Annie R., Wu, Cindy, Bee, Gavyn Chern Wei, Pironti, Alejandro, Putzel, Gregory, Aggarwal, Surya D., Eichner, Hannes, Weiser, Jeffrey N.
Publicado 2023

SynerClust: a highly scalable, synteny-aware orthologue clustering tool

por Georgescu, Christophe H., Manson, Abigail L., Griggs, Alexander D., Desjardins, Christopher A., Pironti, Alejandro, Wapinski, Ilan, Abeel, Thomas, Haas, Brian J., Earl, Ashlee M.
Publicado 2018

Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization

por Ilmain, Juliana K., Perelman, Sofya S., Panepinto, Maria C., Irnov, Irnov, Coudray, Nicolas, Samhadaneh, Nora, Pironti, Alejandro, Ueberheide, Beatrix, Ekiert, Damian C., Bhabha, Gira, Torres, Victor J.
Publicado 2023

geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data

por Döring, Matthias, Büch, Joachim, Friedrich, Georg, Pironti, Alejandro, Kalaghatgi, Prabhav, Knops, Elena, Heger, Eva, Obermeier, Martin, Däumer, Martin, Thielen, Alexander, Kaiser, Rolf, Lengauer, Thomas, Pfeifer, Nico
Publicado 2018

Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics

por Ma, Peijun, He, Lorrie L, Pironti, Alejandro, Laibinis, Hannah H, Ernst, Christoph M, Manson, Abigail L, Bhattacharyya, Roby P, Earl, Ashlee M, Livny, Jonathan, Hung, Deborah T
Publicado 2021

Parameters Influencing Baseline HIV-1 Genotypic Tropism Testing Related to Clinical Outcome in Patients on Maraviroc

por Sierra, Saleta, Dybowski, J. Nikolai, Pironti, Alejandro, Heider, Dominik, Güney, Lisa, Thielen, Alex, Reuter, Stefan, Esser, Stefan, Fätkenheuer, Gerd, Lengauer, Thomas, Hoffmann, Daniel, Pfister, Herbert, Jensen, Björn, Kaiser, Rolf
Publicado 2015

Pathogen Species Is Associated With Mortality in Nosocomial Bloodstream Infection in Patients With COVID-19

por Gago, Juan, Filardo, Thomas D, Conderino, Sarah, Magaziner, Samuel J, Dubrovskaya, Yanina, Inglima, Kenneth, Iturrate, Eduardo, Pironti, Alejandro, Schluter, Jonas, Cadwell, Ken, Hochman, Sarah, Li, Huilin, Torres, Victor J, Thorpe, Lorna E, Shopsin, Bo
Publicado 2022

Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares

por Azzouz, Doua F, Chen, Ze, Izmirly, Peter M, Chen, Lea Ann, Li, Zhi, Zhang, Chongda, Mieles, David, Trujillo, Kate, Heguy, Adriana, Pironti, Alejandro, Putzel, Greg G, Schwudke, Dominik, Fenyo, David, Buyon, Jill P, Alekseyenko, Alexander V, Gisch, Nicolas, Silverman, Gregg J
Publicado 2023

Clostridia isolated from helminth-colonized humans promote the life cycle of Trichuris species

por Sargsian, Shushan, Chen, Ze, Lee, Soo Ching, Robertson, Amicha, Thur, Rafaela Saes, Sproch, Julia, Devlin, Joseph C., Tee, Mian Zi, Er, Yi Xian, Copin, Richard, Heguy, Adriana, Pironti, Alejandro, Torres, Victor J., Ruggles, Kelly V., Lim, Yvonne A.L., Bethony, Jeffrey, Loke, P’ng, Cadwell, Ken
Publicado 2022

Capsular Polysaccharide Is Essential for the Virulence of the Antimicrobial-Resistant Pathogen Enterobacter hormaechei

por St. John, Amelia, Perault, Andrew I., Giacometti, Sabrina I., Sommerfield, Alexis G., DuMont, Ashley L., Lacey, Keenan A., Zheng, Xuhui, Sproch, Julia, Petzold, Chris, Dancel-Manning, Kristen, Gonzalez, Sandra, Annavajhala, Medini, Beckford, Colleen, Zeitouni, Nathalie, Liang, Feng-Xia, van Bakel, Harm, Shopsin, Bo, Uhlemann, Anne-Catrin, Pironti, Alejandro, Torres, Victor J.
Publicado 2023

Simultaneous detection of genotype and phenotype enables rapid and accurate antibiotic susceptibility determination

por Bhattacharyya, Roby P., Bandyopadhyay, Nirmalya, Ma, Peijun, Son, Sophie S., Liu, Jamin, He, Lorrie L., Wu, Lidan, Khafizov, Rustem, Boykin, Rich, Cerqueira, Gustavo C., Pironti, Alejandro, Rudy, Robert F., Patel, Milesh M., Yang, Rui, Skerry, Jennifer, Nazarian, Elizabeth, Musser, Kimberly A., Taylor, Jill, Pierce, Virginia M., Earl, Ashlee M., Cosimi, Lisa A., Shoresh, Noam, Beechem, Joseph, Livny, Jonathan, Hung, Deborah T.
Publicado 2019

Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress

por Podkowik, Magdalena, Perault, Andrew I., Putzel, Gregory, Pountain, Andrew, Kim, Jisun, Dumont, Ashley, Zwack, Erin, Ulrich, Robert J., Karagounis, Theodora K., Zhou, Chunyi, Haag, Andreas F., Shenderovich, Julia, Wasserman, Gregory A., Kwon, Junbeom, Chen, John, Richardson, Anthony R., Weiser, Jeffrey N., Nowosad, Carla R., Lun, Desmond S., Parker, Dane, Pironti, Alejandro, Zhao, Xilin, Drlica, Karl, Yanai, Itai, Torres, Victor J., Shopsin, Bo
Publicado 2023

Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation

por Venzon, Mericien, Bernard-Raichon, Lucie, Klein, Jon, Axelrad, Jordan E., Zhang, Chenzhen, Hussey, Grant A., Sullivan, Alexis P., Casanovas-Massana, Arnau, Noval, Maria G., Valero-Jimenez, Ana M., Gago, Juan, Putzel, Gregory, Pironti, Alejandro, Wilder, Evan, Thorpe, Lorna E., Littman, Dan R., Dittmann, Meike, Stapleford, Kenneth A., Shopsin, Bo, Torres, Victor J., Ko, Albert I., Iwasaki, Akiko, Cadwell, Ken, Schluter, Jonas
Publicado 2022

Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia

por Bernard-Raichon, Lucie, Venzon, Mericien, Klein, Jon, Axelrad, Jordan E., Zhang, Chenzhen, Sullivan, Alexis P., Hussey, Grant A., Casanovas-Massana, Arnau, Noval, Maria G., Valero-Jimenez, Ana M., Gago, Juan, Putzel, Gregory, Pironti, Alejandro, Wilder, Evan, Thorpe, Lorna E., Littman, Dan R., Dittmann, Meike, Stapleford, Kenneth A., Shopsin, Bo, Torres, Victor J., Ko, Albert I., Iwasaki, Akiko, Cadwell, Ken, Schluter, Jonas
Publicado 2022