“Road Map” to Improving Enrollment in Cardiac Rehabilitation: Identifying Barriers and Evaluating Alternatives

por Pirruccello, James P., Traynor, Kathleen, Aragam, Krishna G.
Publicado 2017

A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy

por Kuwabara, Yasuhide, York, Allen J., Lin, Suh-Chin, Sargent, Michelle A., Grimes, Kelly M., Pirruccello, James P., Molkentin, Jeffery D.
Publicado 2023

Elevated Blood Pressure Increases Pneumonia Risk: Epidemiological Association and Mendelian Randomization in the UK Biobank

por Zekavat, Seyedeh M., Honigberg, Michael, Pirruccello, James P., Kohli, Puja, Karlson, Elizabeth W., Newton-Cheh, Christopher, Zhao, Hongyu, Natarajan, Pradeep
Publicado 2021

Genetic Association of Body Mass Index With Pathologic Left Ventricular Remodeling

por Biddinger, Kiran J., Pirruccello, James P., Khurshid, Shaan, Natarajan, Pradeep, Ho, Jennifer E., Lubitz, Steven A., Ellinor, Patrick T., Aragam, Krishna G.
Publicado 2022

Wearable accelerometer-derived physical activity and incident disease

por Khurshid, Shaan, Weng, Lu-Chen, Nauffal, Victor, Pirruccello, James P., Venn, Rachael A., Al-Alusi, Mostafa A., Benjamin, Emelia J., Ellinor, Patrick T., Lubitz, Steven A.
Publicado 2022

The Cardiovascular Impact and Genetics of Pericardial Adiposity

por Rämö, Joel T, Kany, Shinwan, Hou, Cody R, Friedman, Samuel F, Roselli, Carolina, Nauffal, Victor, Koyama, Satoshi, Karjalainen, Juha, Maddah, Mahnaz, Palotie, Aarno, Ellinor, Patrick T, Pirruccello, James P
Publicado 2023

AORTA Gene: Polygenic prediction improves detection of thoracic aortic aneurysm

por Pirruccello, James P., Khurshid, Shaan, Lin, Honghuang, Lu-Chen, Weng, Zamirpour, Siavash, Kany, Shinwan, Raghavan, Avanthi, Koyama, Satoshi, Vasan, Ramachandran S., Benjamin, Emelia J., Lindsay, Mark E., Ellinor, Patrick T.
Publicado 2023

Deep learning to estimate cardiac magnetic resonance–derived left ventricular mass

por Khurshid, Shaan, Friedman, Samuel Freesun, Pirruccello, James P., Di Achille, Paolo, Diamant, Nathaniel, Anderson, Christopher D., Ellinor, Patrick T., Batra, Puneet, Ho, Jennifer E., Philippakis, Anthony A., Lubitz, Steven A.
Publicado 2021

Association of genetic risk and outcomes in patients with atrial fibrillation: interactions with early rhythm control in the EAST-AFNET4 trial

por Kany, Shinwan, Al-Taie, Christoph, Roselli, Carolina, Pirruccello, James P, Borof, Katrin, Reinbold, Carla, Suling, Anna, Krause, Linda, Reissmann, Bruno, Schnabel, Renate B, Zeller, Tanja, Zapf, Antonia, Wegscheider, Karl, Fabritz, Larissa, Ellinor, Patrick T, Kirchhof, Paulus
Publicado 2023

Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass

por Khurshid, Shaan, Lazarte, Julieta, Pirruccello, James P., Weng, Lu-Chen, Choi, Seung Hoan, Hall, Amelia W., Wang, Xin, Friedman, Samuel F., Nauffal, Victor, Biddinger, Kiran J., Aragam, Krishna G., Batra, Puneet, Ho, Jennifer E., Philippakis, Anthony A., Ellinor, Patrick T., Lubitz, Steven A.
Publicado 2023

Machine learning enables new insights into genetic contributions to liver fat accumulation

por Haas, Mary E., Pirruccello, James P., Friedman, Samuel N., Wang, Minxian, Emdin, Connor A., Ajmera, Veeral H., Simon, Tracey G., Homburger, Julian R., Guo, Xiuqing, Budoff, Matthew, Corey, Kathleen E., Zhou, Alicia Y., Philippakis, Anthony, Ellinor, Patrick T., Loomba, Rohit, Batra, Puneet, Khera, Amit V.
Publicado 2021

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

por Pirruccello, James P., Bick, Alexander, Wang, Minxian, Chaffin, Mark, Friedman, Samuel, Yao, Jie, Guo, Xiuqing, Venkatesh, Bharath Ambale, Taylor, Kent D., Post, Wendy S., Rich, Stephen, Lima, Joao A. C., Rotter, Jerome I., Philippakis, Anthony, Lubitz, Steven A., Ellinor, Patrick T., Khera, Amit V., Kathiresan, Sekar, Aragam, Krishna G.
Publicado 2020

Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

por Jurgens, Sean J., Choi, Seung Hoan, Morrill, Valerie N., Chaffin, Mark, Pirruccello, James P., Halford, Jennifer L., Weng, Lu-Chen, Nauffal, Victor, Roselli, Carolina, Hall, Amelia W., Oetjens, Matthew T., Lagerman, Braxton, vanMaanen, David P., Aragam, Krishna G., Lunetta, Kathryn L., Haggerty, Christopher M., Lubitz, Steven A., Ellinor, Patrick T.
Publicado 2022

Genetics of 35 blood and urine biomarkers in the UK Biobank

por Armstrong, Nasa Sinnott-, Tanigawa, Yosuke, Amar, David, Mars, Nina, Benner, Christian, Aguirre, Matthew, Venkataraman, Guhan Ram, Wainberg, Michael, Ollila, Hanna M., Kiiskinen, Tuomo, Havulinna, Aki S., Pirruccello, James P., Qian, Junyang, Shcherbina, Anna, consortium, FinnGen, Rodriguez, Fatima, Assimes, Themistocles L., Agarwala, Vineeta, Tibshirani, Robert, Hastie, Trevor, Ripatti, Samuli, Pritchard, Jonathan K., Daly, Mark J., Rivas, Manuel A.
Publicado 2021

Selenoprotein deficiency disorder predisposes to aortic aneurysm formation

por Schoenmakers, Erik, Marelli, Federica, Jørgensen, Helle F., Visser, W. Edward, Moran, Carla, Groeneweg, Stefan, Avalos, Carolina, Jurgens, Sean J., Figg, Nichola, Finigan, Alison, Wali, Neha, Agostini, Maura, Wardle-Jones, Hannah, Lyons, Greta, Rusk, Rosemary, Gopalan, Deepa, Twiss, Philip, Visser, Jacob J., Goddard, Martin, Nashef, Samer A. M., Heijmen, Robin, Clift, Paul, Sinha, Sanjay, Pirruccello, James P., Ellinor, Patrick T., Busch-Nentwich, Elisabeth M., Ramirez-Solis, Ramiro, Murphy, Michael P., Persani, Luca, Bennett, Martin, Chatterjee, Krishna
Publicado 2023

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

por Zekavat, Seyedeh M., Lin, Shu-Hong, Bick, Alexander G., Liu, Aoxing, Paruchuri, Kaavya, Uddin, Md Mesbah, Ye, Yixuan, Yu, Zhaolong, Liu, Xiaoxi, Kamatani, Yoichiro, Pirruccello, James P., Pampana, Akhil, Loh, Po-Ru, Kohli, Puja, McCarroll, Steven A., Neale, Benjamin, Engels, Eric A., Brown, Derek W., Smoller, Jordan W., Green, Robert, Karlson, Elizabeth W., Lebo, Matthew, Ellinor, Patrick T., Weiss, Scott T., Daly, Mark J., Terao, Chikashi, Zhao, Hongyu, Ebert, Benjamin L., Ganna, Andrea, Machiela, Mitchell J., Genovese, Giulio, Natarajan, Pradeep
Publicado 2020

Deep learning enables genetic analysis of the human thoracic aorta

por Pirruccello, James P., Chaffin, Mark D., Chou, Elizabeth L., Fleming, Stephen J., Lin, Honghuang, Nekoui, Mahan, Khurshid, Shaan, Friedman, Samuel N., Bick, Alexander G., Arduini, Alessandro, Weng, Lu-Chen, Choi, Seung Hoan, Akkad, Amer-Denis, Batra, Puneet, Tucker, Nathan R., Hall, Amelia W., Roselli, Carolina, Benjamin, Emelia J., Vellarikkal, Shamsudheen K., Gupta, Rajat M., Stegmann, Christian M., Juric, Dejan, Stone, James R., Vasan, Ramachandran S., Ho, Jennifer E., Hoffmann, Udo, Lubitz, Steven A., Philippakis, Anthony A., Lindsay, Mark E., Ellinor, Patrick T.
Publicado 2022

Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program

por Klarin, Derek, Devineni, Poornima, Sendamarai, Anoop K., Angueira, Anthony R., Graham, Sarah E., Shen, Ying H., Levin, Michael G., Pirruccello, James P., Surakka, Ida, Karnam, Purushotham R., Roychowdhury, Tanmoy, Li, Yanming, Wang, Minxian, Aragam, Krishna G., Paruchuri, Kaavya, Zuber, Verena, Shakt, Gabrielle E., Tsao, Noah L., Judy, Renae L., Vy, Ha My T., Verma, Shefali S., Rader, Daniel J., Do, Ron, Bavaria, Joseph E., Nadkarni, Girish N., Ritchie, Marylyn D., Burgess, Stephen, Guo, Dong-chuan, Ellinor, Patrick T., LeMaire, Scott A., Milewicz, Dianna M., Willer, Cristen J., Natarajan, Pradeep, Tsao, Philip S., Pyarajan, Saiju, Damrauer, Scott M.
Publicado 2023

Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes

por Halford, Jennifer L., Morrill, Valerie N., Choi, Seung Hoan, Jurgens, Sean J., Melloni, Giorgio, Marston, Nicholas A., Weng, Lu-Chen, Nauffal, Victor, Hall, Amelia W., Gunn, Sophia, Austin-Tse, Christina A., Pirruccello, James P., Khurshid, Shaan, Rehm, Heidi L., Benjamin, Emelia J., Boerwinkle, Eric, Brody, Jennifer A., Correa, Adolfo, Fornwalt, Brandon K., Gupta, Namrata, Haggerty, Christopher M., Harris, Stephanie, Heckbert, Susan R., Hong, Charles C., Kooperberg, Charles, Lin, Henry J., Loos, Ruth J. F., Mitchell, Braxton D., Morrison, Alanna C., Post, Wendy, Psaty, Bruce M., Redline, Susan, Rice, Kenneth M., Rich, Stephen S., Rotter, Jerome I., Schnatz, Peter F., Soliman, Elsayed Z., Sotoodehnia, Nona, Wong, Eugene K., Sabatine, Marc S., Ruff, Christian T., Lunetta, Kathryn L., Ellinor, Patrick T., Lubitz, Steven A.
Publicado 2022

Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes

por Halford, Jennifer L., Morrill, Valerie N., Choi, Seung Hoan, Jurgens, Sean J., Melloni, Giorgio, Marston, Nicholas A., Weng, Lu-Chen, Nauffal, Victor, Hall, Amelia W., Gunn, Sophia, Austin-Tse, Christina A., Pirruccello, James P., Khurshid, Shaan, Rehm, Heidi L., Benjamin, Emelia J., Boerwinkle, Eric, Brody, Jennifer A., Correa, Adolfo, Fornwalt, Brandon K., Gupta, Namrata, Haggerty, Christopher M., Harris, Stephanie, Heckbert, Susan R., Hong, Charles C., Kooperberg, Charles, Lin, Henry J., Loos, Ruth J. F., Mitchell, Braxton D., Morrison, Alanna C., Post, Wendy, Psaty, Bruce M., Redline, Susan, Rice, Kenneth M., Rich, Stephen S., Rotter, Jerome I., Schnatz, Peter F., Soliman, Elsayed Z., Sotoodehnia, Nona, Wong, Eugene K., Sabatine, Marc S., Ruff, Christian T., Lunetta, Kathryn L., Ellinor, Patrick T., Lubitz, Steven A.
Publicado 2022