The ubiquitin-conjugating enzyme UBE2E3 and its import receptor importin-11 regulate the localization and activity of the antioxidant transcription factor NRF2

por Plafker, Kendra S., Plafker, Scott M.
Publicado 2015

Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina

por Mirza, Saima, Plafker, Kendra S., Aston, Christopher, Plafker, Scott M.
Publicado 2010

Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence

por Plafker, Kendra S., Zyla, Katarzyna, Berry, William, Plafker, Scott M.
Publicado 2018

Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission

por O'Mealey, Gary B., Berry, William L., Plafker, Scott M.
Publicado 2016

Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import

por Plafker, Scott M., Plafker, Kendra S., Weissman, Allan M., Macara, Ian G.
Publicado 2004

Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons

por Larabee, Chelsea M., Georgescu, Constantin, Wren, Jonathan D., Plafker, Scott M.
Publicado 2015

Overview of diet and autoimmune demyelinating optic neuritis: a narrative review

por Plafker, Scott M., Titcomb, Tyler, Zyla-Jackson, Katarzyna, Kolakowska, Aneta, Wahls, Terry
Publicado 2023

Sulforaphane recovers cone function in an Nrf2-dependent manner in middle-aged mice undergoing RPE oxidative stress

por Qi, Xiaoping, Walton, Dorothy A., Plafker, Kendra S., Boulton, Michael E., Plafker, Scott M.
Publicado 2022

The Ubiquitin-Conjugating Enzyme, UbcM2, Is Restricted to Monoubiquitylation by a Two-Fold Mechanism That Involves Backside Residues of E2 and Lys48 of Ubiquitin

por Nguyen, Linda, Plafker, Kendra S., Starnes, Andrew, Cook, Matt, Klevit, Rachel E., Plafker, Scott M.
Publicado 2014

Dimethyl fumarate mitigates optic neuritis

por Zyla, Katarzyna, Larabee, Chelsea M., Georgescu, Constantin, Berkley, Chelsea, Reyna, Tania, Plafker, Scott M.
Publicado 2019

Regulation of Nrf2 by X Box-Binding Protein 1 in Retinal Pigment Epithelium

por Chen, Chen, Zhong, Yimin, Wang, Joshua J., Yu, Qiang, Plafker, Kendra, Plafker, Scott, Zhang, Sarah X.
Publicado 2018

Myelin-specific Th17 cells induce severe relapsing optic neuritis with irreversible loss of retinal ganglion cells in C57BL/6 mice

por Larabee, Chelsea M., Hu, Yang, Desai, Shruti, Georgescu, Constantin, Wren, Jonathan D., Axtell, Robert C., Plafker, Scott M.
Publicado 2016

Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis

por Larabee, Chelsea M., Desai, Shruti, Agasing, Agnieshka, Georgescu, Constantin, Wren, Jonathan D., Axtell, Robert C., Plafker, Scott M.
Publicado 2016

Dietary protection against the visual and motor deficits induced by experimental autoimmune encephalomyelitis

por Zyla-Jackson, Katarzyna, Walton, Dorothy A., Plafker, Kendra S., Kovats, Susan, Georgescu, Constantin, Brush, Richard S., Tytanic, Madison, Agbaga, Martin-Paul, Plafker, Scott M.
Publicado 2023

Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis

por Bhaskaran, Shylesh, Kumar, Gaurav, Thadathil, Nidheesh, Piekarz, Katarzyna M., Mohammed, Sabira, Lopez, Sergio Dominguez, Qaisar, Rizwan, Walton, Dorothy, Brown, Jacob L., Murphy, Ashley, Smith, Nataliya, Saunders, Debra, Beckstead, Michael J., Plafker, Scott, Lewis, Tommy L., Towner, Rheal, Deepa, Sathyaseelan S., Richardson, Arlan, Axtell, Robert C., Van Remmen, Holly
Publicado 2022

The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein

por Chen, Muhan, Nowak, Dawid G., Narula, Navneet, Robinson, Brian, Watrud, Kaitlin, Ambrico, Alexandra, Herzka, Tali M., Zeeman, Martha E., Minderer, Matthias, Zheng, Wu, Ebbesen, Saya H., Plafker, Kendra S., Stahlhut, Carlos, Wang, Victoria M.Y., Wills, Lorna, Nasar, Abu, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Wilkinson, John E., Powers, Scott, Sordella, Raffaella, Altorki, Nasser K., Mittal, Vivek, Stiles, Brendon M., Plafker, Scott M., Trotman, Lloyd C.
Publicado 2017