Choreography of methylation: KDM4C histone demethylation enables ALKBH5 m6A RNA demethylation to sustain AML stem cells

por Sarma, Pranjal, Plas, David R.
Publicado 2020

IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels

por Raynor, Jana, Sholl, Allyson, Plas, David R., Bouillet, Philippe, Chougnet, Claire A., Hildeman, David A.
Publicado 2013

S6K1 determines the metabolic requirements for BCR-ABL survival

por Barger, Jennifer F., Gallo, Catherine A., Tandon, Preeti, Liu, Hongqi, Sullivan, Ashley, Grimes, H. Leighton, Plas, David R.
Publicado 2012

mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching

por Shin, Sejeong, Han, Min-Joon, Jedrychowski, Mark P., Zhang, Ziyang, Shokat, Kevan M., Plas, David R., Dephoure, Noah, Yoon, Sang-Oh
Publicado 2023

Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma

por Czyzyk-Krzeska, Maria F., Landero Figueroa, Julio A., Gulati, Shuchi, Cunningham, John T., Meller, Jarek, ShamsaeI, Behrouz, Vemuri, Bhargav, Plas, David R.
Publicado 2021

Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells

por Wang, Chenran, Haas, Michael A., Yang, Fuchun, Yeo, Syn, Okamoto, Takako, Chen, Song, Wen, Jian, Sarma, Pranjal, Plas, David R., Guan, Jun-Lin
Publicado 2019

Chromatin structure predicts survival in glioma patients

por Garrett, Matthew C., Albano, Rebecca, Carnwath, Troy, Shah, Sanjit, Woo, Daniel, Lamba, Michael, Plas, David R., Paranjpe, Aditi, Roskin, Krishna, Zhao, Chuntao, Lu, Richard
Publicado 2022

ERRα regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism

por Berman, Adi Y, Manna, Subrata, Schwartz, Naomi S, Katz, Yardena E, Sun, Yang, Behrmann, Catherine A, Yu, Jane J, Plas, David R, Alayev, Anya, Holz, Marina K
Publicado 2017

Selective MAP1LC3C (LC3C) autophagy requires noncanonical regulators and the C-terminal peptide

por Bischoff, Megan E., Zang, Yuanwei, Chu, Johnson, Price, Adam D., Ehmer, Birgit, Talbot, Nicholas J., Newbold, Michael J., Paul, Anurag, Guan, Jun-Lin, Plas, David R., Meller, Jarek, Czyzyk-Krzeska, Maria F.
Publicado 2021

Reuse of Molecules for Glioblastoma Therapy

por Koehler, Abigail, Karve, Aniruddha, Desai, Pankaj, Arbiser, Jack, Plas, David R., Qi, Xiaoyang, Read, Renee D., Sasaki, Atsuo T., Gawali, Vaibhavkumar S., Toukam, Donatien K., Bhattacharya, Debanjan, Kallay, Laura, Pomeranz Krummel, Daniel A., Sengupta, Soma
Publicado 2021

Microtubule-associated protein MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells

por Verma, Rita, Aggarwal, Parul, Bischoff, Megan E., Reigle, James, Secic, Dina, Wetzel, Collin, VandenHeuvel, Katherine, Biesiada, Jacek, Ehmer, Birgit, Landero Figueroa, Julio A., Plas, David R., Medvedovic, Mario, Meller, Jarek, Czyzyk-Krzeska, Maria F.
Publicado 2023

HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma

por Garrett, Matthew C., Albano, Rebecca, Carnwath, Troy, Elahi, Lubayna, Behrmann, Catherine A., Pemberton, Merissa, Woo, Daniel, O’Brien, Eric, VanCauwenbergh, Brett, Perentesis, John, Shah, Sanjit, Hagan, Matthew, Kendler, Ady, Zhao, Chuntao, Paranjpe, Aditi, Roskin, Krishna, Kornblum, Harley, Plas, David R., Lu, Q. Richard
Publicado 2023