Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer

por Chen, Binbin, Platt, Manu O
Publicado 2011

From GRID to gridlock: the relationship between scientific biomedical breakthroughs and HIV/AIDS policy in the US Congress

por Platt, Matthew B, Platt, Manu O
Publicado 2013

Challenges and Opportunities Modeling the Dynamic Tumor Matrisome

por Peyton, Shelly R., Platt, Manu O., Cukierman, Edna
Publicado 2023

Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells

por Keegan, Philip M., Surapaneni, Sindhuja, Platt, Manu O.
Publicado 2012

Monocyte-derived macrophage assisted breast cancer cell invasion as a personalized, predictive metric to score metastatic risk

por Park, Keon-Young, Li, Gande, Platt, Manu O.
Publicado 2015

Analysis of structural effects of sickle cell disease on brain vasculature of mice using three-dimensional quantitative phase imaging

por Filan, Caroline, Song, Hannah, Platt, Manu O., Robles, Francisco E.
Publicado 2023

Cysteine cathepsins are altered by flow within an engineered in vitro microvascular niche

por Douglas, Simone A., Haase, Kristina, Kamm, Roger D., Platt, Manu O.
Publicado 2020

Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis

por Parks, Akia N., Nahata, Juhi, Edouard, Naomi-Eliana, Temenoff, Johnna S., Platt, Manu O.
Publicado 2019

Predicting Functional Responses of Progenitor Cell Exosome Potential with Computational Modeling

por Trac, David, Hoffman, Jessica R., Bheri, Sruti, Maxwell, Joshua T., Platt, Manu O., Davis, Michael E.
Publicado 2019

Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines

por Cvetkovic, Caroline, Ferrall-Fairbanks, Meghan C., Ko, Eunkyung, Grant, Lauren, Kong, Hyunjoon, Platt, Manu O., Bashir, Rashid
Publicado 2017

Multiple sites on SARS‐CoV‐2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V

por Bollavaram, Keval, Leeman, Tiffanie H., Lee, Maggie W., Kulkarni, Akhil, Upshaw, Sophia G., Yang, Jiabei, Song, Hannah, Platt, Manu O.
Publicado 2021

Sickle cell disease promotes sex-dependent pathological bone loss through enhanced cathepsin proteolytic activity in mice

por Selma, Jada, Song, Hannah, Rivera, Christian, Douglas, Simone, Akella, Abhiramgopal, Bollavaram, Keval, Thompson, Nishone, Platt, Manu O., Botchwey, Edward A.
Publicado 2022

Tumor cell–organized fibronectin maintenance of a dormant breast cancer population

por Barney, Lauren E., Hall, Christopher L., Schwartz, Alyssa D., Parks, Akia N., Sparages, Christopher, Galarza, Sualyneth, Platt, Manu O., Mercurio, Arthur M., Peyton, Shelly R.
Publicado 2020

Statistical modeling of extracellular vesicle cargo to predict clinical trial outcomes for hypoplastic left heart syndrome

por Hoffman, Jessica R., Park, Hyun-Ji, Bheri, Sruti, Platt, Manu O., Hare, Joshua M., Kaushal, Sunjay, Bettencourt, Judith L., Lai, Dejian, Slesnick, Timothy C., Mahle, William T., Davis, Michael E.
Publicado 2023

Age-Dependent Effect of Pediatric Cardiac Progenitor Cells After Juvenile Heart Failure

por Agarwal, Udit, Smith, Amanda W., French, Kristin M., Boopathy, Archana V., George, Alex, Trac, David, Brown, Milton E., Shen, Ming, Jiang, Rong, Fernandez, Janet D., Kogon, Brian E., Kanter, Kirk R., Alsoufi, Baahaldin, Wagner, Mary B., Platt, Manu O., Davis, Michael E.
Publicado 2016