Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo

por Nieswandt, Bernhard, Moser, Markus, Pleines, Irina, Varga-Szabo, David, Monkley, Sue, Critchley, David, Fässler, Reinhard
Publicado 2007

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

por Varga-Szabo, David, Braun, Attila, Kleinschnitz, Christoph, Bender, Markus, Pleines, Irina, Pham, Mirko, Renné, Thomas, Stoll, Guido, Nieswandt, Bernhard
Publicado 2008

Coactosin-like 1 integrates signaling critical for shear-dependent thrombus formation in mouse platelets

por Scheller, Inga, Stritt, Simon, Beck, Sarah, Peng, Bing, Pleines, Irina, Heinze, Katrin G., Braun, Attila, Otto, Oliver, Ahrends, Robert, Sickmann, Albert, Bender, Markus, Nieswandt, Bernhard
Publicado 2020

Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice

por Englert, Maximilian, Aurbach, Katja, Becker, Isabelle C., Gerber, Annika, Heib, Tobias, Wackerbarth, Lou M., Kusch, Charly, Mott, Kristina, Araujo, Gabriel H. M., Baig, Ayesha A., Dütting, Sebastian, Knaus, Ulla G., Stigloher, Christian, Schulze, Harald, Nieswandt, Bernhard, Pleines, Irina, Nagy, Zoltan
Publicado 2022

Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

por Schevzov, Galina, Kee, Anthony J., Wang, Bin, Sequeira, Vanessa B., Hook, Jeff, Coombes, Jason D., Lucas, Christine A., Stehn, Justine R., Musgrove, Elizabeth A., Cretu, Alexandra, Assoian, Richard, Fath, Thomas, Hanoch, Tamar, Seger, Rony, Pleines, Irina, Kile, Benjamin T., Hardeman, Edna C., Gunning, Peter W.
Publicado 2015

G6b-B regulates an essential step in megakaryocyte maturation

por Becker, Isabelle C., Nagy, Zoltan, Manukjan, Georgi, Haffner-Luntzer, Melanie, Englert, Maximilian, Heib, Tobias, Vögtle, Timo, Gross, Carina, Bharti, Richa, Dietrich, Sascha, Mott, Kristina, Heck, Johannes, Stegmaier, Sebastian, Baranowsky, Anke, Schinke, Thorsten, Schlegel, Nicolas, Heckel, Tobias, Stegner, David, Pleines, Irina, Ignatius, Anita, Schulze, Harald, Nieswandt, Bernhard
Publicado 2022

An essential role for α4A-tubulin in platelet biogenesis

por Strassel, Catherine, Magiera, Maria M, Dupuis, Arnaud, Batzenschlager, Morgane, Hovasse, Agnès, Pleines, Irina, Guéguen, Paul, Eckly, Anita, Moog, Sylvie, Mallo, Léa, Kimmerlin, Quentin, Chappaz, Stéphane, Strub, Jean-Marc, Kathiresan, Natarajan, de la Salle, Henri, Van Dorsselaer, Alain, Ferec, Claude, Py, Jean-Yves, Gachet, Christian, Schaeffer-Reiss, Christine, Kile, Benjamin T, Janke, Carsten, Lanza, François
Publicado 2019

Correction: An essential role for α4A-tubulin in platelet biogenesis

por Strassel, Catherine, Magiera, Maria M, Dupuis, Arnaud, Batzenschlager, Morgane, Hovasse, Agnès, Pleines, Irina, Guéguen, Paul, Eckly, Anita, Moog, Sylvie, Mallo, Léa, Kimmerlin, Quentin, Chappaz, Stéphane, Strub, Jean-Marc, Kathiresan, Natarajan, de la Salle, Henri, Van Dorsselaer, Alain, Ferec, Claude, Py, Jean-Yves, Gachet, Christian, Schaeffer-Reiss, Christine, Kile, Benjamin T, Janke, Carsten, Lanza, François
Publicado 2021

Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis

por Nagy, Magdolna, van Geffen, Johanna P., Stegner, David, Adams, David J., Braun, Attila, de Witt, Susanne M., Elvers, Margitta, Geer, Mitchell J., Kuijpers, Marijke J. E., Kunzelmann, Karl, Mori, Jun, Oury, Cécile, Pircher, Joachim, Pleines, Irina, Poole, Alastair W., Senis, Yotis A., Verdoold, Remco, Weber, Christian, Nieswandt, Bernhard, Heemskerk, Johan W. M., Baaten, Constance C. F. M. J.
Publicado 2019

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

por Dütting, Sebastian, Gaits-Iacovoni, Frederique, Stegner, David, Popp, Michael, Antkowiak, Adrien, van Eeuwijk, Judith M.M., Nurden, Paquita, Stritt, Simon, Heib, Tobias, Aurbach, Katja, Angay, Oguzhan, Cherpokova, Deya, Heinz, Niels, Baig, Ayesha A., Gorelashvili, Maximilian G., Gerner, Frank, Heinze, Katrin G., Ware, Jerry, Krohne, Georg, Ruggeri, Zaverio M., Nurden, Alan T., Schulze, Harald, Modlich, Ute, Pleines, Irina, Brakebusch, Cord, Nieswandt, Bernhard
Publicado 2017

Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia

por Pleines, Irina, Woods, Joanne, Chappaz, Stephane, Kew, Verity, Foad, Nicola, Ballester-Beltrán, José, Aurbach, Katja, Lincetto, Chiara, Lane, Rachael M., Schevzov, Galina, Alexander, Warren S., Hilton, Douglas J., Astle, William J., Downes, Kate, Nurden, Paquita, Westbury, Sarah K., Mumford, Andrew D., Obaji, Samya G., Collins, Peter W., Delerue, Fabien, Ittner, Lars M., Bryce, Nicole S., Holliday, Mira, Lucas, Christine A., Hardeman, Edna C., Ouwehand, Willem H., Gunning, Peter W., Turro, Ernest, Tijssen, Marloes R., Kile, Benjamin T.
Publicado 2017