GWASs and the age of human as the model organism for autoimmune genetic research

por Plenge, Robert
Publicado 2010

Rare protection against type 1 diabetes

por Plenge, Robert M
Publicado 2009

Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigar...

por Costenbader, Karen H, Chang, Shun-Chiao, De Vivo, Immaculata, Plenge, Robert, Karlson, Elizabeth W
Publicado 2008

The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1

por Li, Gang, Cunin, Pierre, Wu, Di, Diogo, Dorothée, Yang, Yu, Okada, Yukinori, Plenge, Robert M., Nigrovic, Peter A.
Publicado 2016

Genetic Risk Score Predicting Risk of Rheumatoid Arthritis Phenotypes and Age of Symptom Onset

por Chibnik, Lori B., Keenan, Brendan T., Cui, Jing, Liao, Katherine P., Costenbader, Karen H., Plenge, Robert M., Karlson, Elizabeth W.
Publicado 2011

Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease

por Hutchinson, John N., Raj, Towfique, Fagerness, Jes, Stahl, Eli, Viloria, Fernando T., Gimelbrant, Alexander, Seddon, Johanna, Daly, Mark, Chess, Andrew, Plenge, Robert
Publicado 2014

Identification of the NF-κB activating protein-like locus as a risk locus for rheumatoid arthritis

por Xie, Gang, Lu, Yue, Sun, Ye, Zhang, Steven Shiyang, Keystone, Edward Clark, Gregersen, Peter K, Plenge, Robert M, Amos, Christopher I, Siminovitch, Katherine A
Publicado 2013

Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study

por Yarwood, Annie, Viatte, Sebastien, Okada, Yukinori, Plenge, Robert, Yamamoto, Kazuhiko, Barton, Anne, Symmons, Deborah, Raychaudhuri, Soumya, Klareskog, Lars, Gregersen, Peter, Worthington, Jane, Eyre, Steve
Publicado 2015

Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis

por Fernando, Michelle M. A., Stevens, Christine R., Walsh, Emily C., De Jager, Philip L., Goyette, Philippe, Plenge, Robert M., Vyse, Timothy J., Rioux, John D.
Publicado 2008

Analysis and Application of European Genetic Substructure Using 300 K SNP Information

por Tian, Chao, Plenge, Robert M, Ransom, Michael, Lee, Annette, Villoslada, Pablo, Selmi, Carlo, Klareskog, Lars, Pulver, Ann E, Qi, Lihong, Gregersen, Peter K, Seldin, Michael F
Publicado 2008

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk

por Yarwood, Annie, Han, Buhm, Raychaudhuri, Soumya, Bowes, John, Lunt, Mark, Pappas, Dimitrios A, Kremer, Joel, Greenberg, Jeffrey D, Plenge, Robert, Worthington, Jane, Barton, Anne, Eyre, Steve
Publicado 2015

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

por Raychaudhuri, Soumya, Plenge, Robert M., Rossin, Elizabeth J., Ng, Aylwin C. Y., Purcell, Shaun M., Sklar, Pamela, Scolnick, Edward M., Xavier, Ramnik J., Altshuler, David, Daly, Mark J.
Publicado 2009

Data for Genetic Analysis Workshop 16 Problem 1, association analysis of rheumatoid arthritis data

por Amos, Christopher I, Chen, Wei Vivien, Seldin, Michael F, Remmers, Elaine F, Taylor, Kimberly E, Criswell, Lindsey A, Lee, Annette T, Plenge, Robert M, Kastner, Daniel L, Gregersen, Peter K
Publicado 2009

TRAF1/C5 locus is associated with response to anti-TNF in rheumatoid arthritis

por Canhão, Helena, Rodrigues, Ana, Santos, Maria Jose, Carmona-Fernandes, Diana, Costa, José, Santos, Helena, Branco, Jaime, Plenge, Robert, Solomon, Daniel, Armas, Jacome, Silva, José António, Fonseca, João Eurico, Karlson, Elizabeth
Publicado 2012

Quantifying Missing Heritability at Known GWAS Loci

por Gusev, Alexander, Bhatia, Gaurav, Zaitlen, Noah, Vilhjalmsson, Bjarni J., Diogo, Dorothée, Stahl, Eli A., Gregersen, Peter K., Worthington, Jane, Klareskog, Lars, Raychaudhuri, Soumya, Plenge, Robert M., Pasaniuc, Bogdan, Price, Alkes L.
Publicado 2013

The Influence of Polygenic Risk Scores on Heritability of Anti-CCP Level in RA

por Cui, Jing, Taylor, Kimberly E., Lee, Yvonne C., Källberg, Henrik, Weinblatt, Michael E., Coblyn, Jonathan S., Klareskog, Lars, Criswell, Lindsey A., Gregersen, Peter K., Shadick, Nancy A., Plenge, Robert M., Karlson, Elizabeth W.
Publicado 2014

Large Scale Metabolic Profiling identifies Novel Steroids linked to Rheumatoid Arthritis

por Yousri, Noha A., Bayoumy, Karim, Elhaq, Wessam Gad, Mohney, Robert P., Emadi, Samar Al, Hammoudeh, Mohammed, Halabi, Hussein, Masri, Basel, Badsha, Humeira, Uthman, Imad, Plenge, Robert, Saxena, Richa, Suhre, Karsten, Arayssi, Thurayya
Publicado 2017

Automatic Prediction of Rheumatoid Arthritis Disease Activity from the Electronic Medical Records

por Lin, Chen, Karlson, Elizabeth W., Canhao, Helena, Miller, Timothy A., Dligach, Dmitriy, Chen, Pei Jun, Perez, Raul Natanael Guzman, Shen, Yuanyan, Weinblatt, Michael E., Shadick, Nancy A., Plenge, Robert M., Savova, Guergana K.
Publicado 2013

Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction

por Klarenbeek, Paul L., Doorenspleet, Marieke E., Esveldt, Rebecca E. E., van Schaik, Barbera D. C., Lardy, Neubury, van Kampen, Antoine H. C., Tak, Paul P., Plenge, Robert M., Baas, Frank, de Bakker, Paul I. W., de Vries, Niek
Publicado 2015

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

por Raychaudhuri, Soumya, Sandor, Cynthia, Stahl, Eli A., Freudenberg, Jan, Lee, Hye-Soon, Jia, Xiaoming, Alfredsson, Lars, Padyukov, Leonid, Klareskog, Lars, Worthington, Jane, Siminovitch, Katherine A., Bae, Sang-Cheol, Plenge, Robert M., Gregersen, Peter K., de Bakker, Paul I.W.
Publicado 2012