Principles of agonist recognition in Cys-loop receptors

por Lynagh, Timothy, Pless, Stephan A.
Publicado 2014

How an intrinsic ligand tunes the activity of a potassium channel

por Khoo, Keith K., Pless, Stephan A.
Publicado 2018

Unique Contributions of an Arginine Side Chain to Ligand Recognition in a Glutamate-gated Chloride Channel

por Lynagh, Timothy, Komnatnyy, Vitaly V., Pless, Stephan A.
Publicado 2017

PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels

por Kim, Robin Y., Pless, Stephan A., Kurata, Harley T.
Publicado 2017

Molecular determinants for agonist recognition and discrimination in P2X2 receptors

por Gasparri, Federica, Wengel, Jesper, Grutter, Thomas, Pless, Stephan A.
Publicado 2019

Contributions of Counter-Charge in a Potassium Channel Voltage-Sensor Domain

por Pless, Stephan A., Galpin, Jason D., Niciforovic, Ana P., Ahern, Christopher A.
Publicado 2011

Conformational decoupling in acid-sensing ion channels uncovers mechanism and stoichiometry of PcTx1-mediated inhibition

por Heusser, Stephanie A, Borg, Christian B, Colding, Janne M, Pless, Stephan A
Publicado 2022

High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology

por Braun, Nina, Friis, Søren, Ihling, Christian, Sinz, Andrea, Andersen, Jacob, Pless, Stephan A.
Publicado 2021

Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels

por Pless, Stephan A, Galpin, Jason D, Niciforovic, Ana P, Kurata, Harley T, Ahern, Christopher A
Publicado 2013

The M1 and pre-M1 segments contribute differently to ion selectivity in ASICs and ENaCs

por Sheikh, Zeshan P., Wulf, Matthias, Friis, Søren, Althaus, Mike, Lynagh, Timothy, Pless, Stephan A.
Publicado 2021

Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels

por Lynagh, Timothy, Flood, Emelie, Boiteux, Céline, Sheikh, Zeshan Pervez, Allen, Toby W., Pless, Stephan A.
Publicado 2020

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel

por Pless, Stephan A., Niciforovic, Ana P., Galpin, Jason D., Nunez, John-Jose, Kurata, Harley T., Ahern, Christopher A.
Publicado 2013

Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

por Pless, Stephan A., Elstone, Fisal D., Niciforovic, Ana P., Galpin, Jason D., Yang, Runying, Kurata, Harley T., Ahern, Christopher A.
Publicado 2014

Atomic basis for therapeutic activation of neuronal potassium channels

por Kim, Robin Y., Yau, Michael C., Galpin, Jason D., Seebohm, Guiscard, Ahern, Christopher A., Pless, Stephan A., Kurata, Harley T.
Publicado 2015

Four drug-sensitive subunits are required for maximal effect of a voltage sensor–targeted KCNQ opener

por Wang, Alice W., Yau, Michael C., Wang, Caroline K., Sharmin, Nazlee, Yang, Runying Y., Pless, Stephan A., Kurata, Harley T.
Publicado 2018

A selectivity filter at the intracellular end of the acid-sensing ion channel pore

por Lynagh, Timothy, Flood, Emelie, Boiteux, Céline, Wulf, Matthias, Komnatnyy, Vitaly V, Colding, Janne M, Allen, Toby W, Pless, Stephan A
Publicado 2017

Intermediate state trapping of a voltage sensor

por Lacroix, Jérôme J., Pless, Stephan A., Maragliano, Luca, Campos, Fabiana V., Galpin, Jason D., Ahern, Christopher A., Roux, Benoît, Bezanilla, Francisco
Publicado 2012

One drug-sensitive subunit is sufficient for a near-maximal retigabine effect in KCNQ channels

por Yau, Michael C., Kim, Robin Y., Wang, Caroline K., Li, Jingru, Ammar, Tarek, Yang, Runying Y., Pless, Stephan A., Kurata, Harley T.
Publicado 2018