Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1–dependent pathway

por Hegazi, Refaat A.F., Rao, Kavitha N., Mayle, Aqila, Sepulveda, Antonia R., Otterbein, Leo E., Plevy, Scott E.
Publicado 2005

Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death

por Tilstra, Jeremy S., Gaddy, Daniel F., Zhao, Jing, Davé, Shaival H., Niedernhofer, Laura J., Plevy, Scott E., Robbins, Paul D.
Publicado 2014

Phosphoinositide 3-Kinase P110δ-Signaling Is Critical for Microbiota-Activated IL-10 Production by B Cells that Regulate Intestinal Inflammation

por Oka, Akihiko, Mishima, Yoshiyuki, Liu, Bo, Herzog, Jeremy W., Steinbach, Erin C., Kobayashi, Taku, Plevy, Scott E., Sartor, R. Balfour
Publicado 2019

A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis

por Elloumi, Houda Z., Maharshak, Nitsan, Rao, Kavitha N., Kobayashi, Taku, Ryu, Hyungjin S., Mühlbauer, Marcus, Li, Fengling, Jobin, Christian, Plevy, Scott E.
Publicado 2012

Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice

por Ellermann, Melissa, Gharaibeh, Raad Z., Maharshak, Nitsan, Peréz-Chanona, Ernesto, Jobin, Christian, Carroll, Ian M., Arthur, Janelle C., Plevy, Scott E, Fodor, Anthony A., Brouwer, Cory R., Sartor, R. Balfour
Publicado 2019

The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis

por Manthey, Carl L., Moore, Beverley A., Chen, Yanqing, Loza, Matthew J., Yao, Xiang, Liu, Hao, Belkowski, Stanley M., Raymond-Parks, Holly, Dunford, Paul J., Leon, Francisco, Towne, Jennifer E., Plevy, Scott E.
Publicado 2019

The intracellular innate immune sensor NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth

por Chen, Liang, Wilson, Justin E., Koenigsknecht, Mark J., Chou, Wei-Chun, Montgomery, Stephanie A., Truax, Agnieszka D., Brickey, W. June, Packey, Christopher D., Maharshak, Nitsan, Matsushima, Glenn K., Plevy, Scott E., Young, Vincent B., Sartor, R. Balfour, Ting, Jenny P-Y
Publicado 2017

Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model

por Goettel, Jeremy A., Kotlarz, Daniel, Emani, Rohini, Canavan, James B., Konnikova, Liza, Illig, David, Frei, Sandra M., Field, Michael, Kowalik, Matthew, Peng, Kaiyue, Gringauz, Jordan, Mitsialis, Vanessa, Wall, Sarah M., Tsou, Amy, Griffith, Alexandra E., Huang, Ying, Friedman, Joshua R., Towne, Jennifer E., Plevy, Scott E., O’Hara Hall, Aisling, Snapper, Scott B.
Publicado 2019

Oncostatin M drives intestinal inflammation in mice and its abundance predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease

por West, Nathaniel R., Hegazy, Ahmed N., Owens, Benjamin M. J., Bullers, Samuel J., Linggi, Bryan, Buonocore, Sofia, Coccia, Margherita, Görtz, Dieter, This, Sébastien, Stockenhuber, Krista, Pott, Johanna, Friedrich, Matthias, Ryzhakov, Grigory, Baribaud, Frédéric, Brodmerkel, Carrie, Cieluch, Constanze, Rahman, Nahid, Müller-Newen, Gerhard, Owens, Raymond J., Kühl, Anja A., Maloy, Kevin J., Plevy, Scott E., Keshav, Satish, Travis, Simon P. L., Powrie, Fiona
Publicado 2017