Bacterial Plasminogen Receptors Utilize Host Plasminogen System for Effective Invasion and Dissemination

por Bhattacharya, Sarbani, Ploplis, Victoria A., Castellino, Francis J.
Publicado 2012

Effect of Sulindac Sulfide on Metallohydrolases in the Human Colon Cancer Cell Line HT-29

por Guillen-Ahlers, Hector, Tan, Jiangning, Castellino, Francis J., Ploplis, Victoria A.
Publicado 2011

Spike protein receptor-binding domains from SARS-CoV-2 variants of interest bind human ACE2 more tightly than the prototype spike protein

por Charles, Jermilia, McCann, Nathan, Ploplis, Victoria A., Castellino, Francis J.
Publicado 2023

Fas/CD95 Deficiency in Apc(Min/+) Mice Increases Intestinal Tumor Burden

por Guillen-Ahlers, Hector, Suckow, Mark A., Castellino, Francis J., Ploplis, Victoria A.
Publicado 2010

Characterization of Atherosclerosis Formation in a Murine Model of Type IIa Human Familial Hypercholesterolemia

por Miyajima, Chiharu, Iwaki, Takayuki, Umemura, Kazuo, Ploplis, Victoria A., Castellino, Francis J.
Publicado 2018

Characterization of Streptokinases from Group A Streptococci Reveals a Strong Functional Relationship That Supports the Coinheritance of Plasminogen-binding M Protein and Cluster 2...

por Zhang, Yueling, Liang, Zhong, Hsueh, Hsing-Tse, Ploplis, Victoria A., Castellino, Francis J.
Publicado 2012

Draft Genome Sequences of Six Skin Isolates of Streptococcus pyogenes

por Liang, Zhong, Stephens, Melissa, Ploplis, Victoria A., Lee, Shaun W., Castellino, Francis J.
Publicado 2018

A deficiency of uPAR alters endothelial angiogenic function and cell morphology

por Balsara, Rashna D, Merryman, Reid, Virjee, Farhaad, Northway, Claire, Castellino, Francis J, Ploplis, Victoria A
Publicado 2011

Phenotypic differentiation of Streptococcus pyogenes populations is induced by recombination-driven gene-specific sweeps

por Bao, Yun-Juan, Shapiro, B. Jesse, Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Publicado 2016

Abrogation of Plasminogen Activator Inhibitor-1-Vitronectin Interaction Ameliorates Acute Kidney Injury in Murine Endotoxemia

por Gupta, Kamlesh K., Donahue, Deborah L., Sandoval-Cooper, Mayra J., Castellino, Francis J., Ploplis, Victoria A.
Publicado 2015

Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation

por Gupta, Kamlesh K., Donahue, Deborah L., Sandoval-Cooper, Mayra J., Castellino, Francis J., Ploplis, Victoria A.
Publicado 2017

Binding of the kringle‐2 domain of human plasminogen to streptococcal PAM‐type M‐protein causes dissociation of PAM dimers

por Ayinuola, Olawole, Ayinuola, Yetunde A., Qiu, Cunjia, Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Publicado 2021

Stable genetic integration of a red fluorescent protein in a virulent Group A Streptococcus strain

por Liang, Zhong, Carothers, Katelyn, Holmes, Adam, Donahue, Deborah, Lee, Shaun W., Castellino, Francis J., Ploplis, Victoria A.
Publicado 2019

Plasminogen and Plasminogen Activators Protect against Renal Injury in Crescentic Glomerulonephritis

por Kitching, A. Richard, Holdsworth, Stephen R., Ploplis, Victoria A., Plow, Edward F., Collen, Désiré, Carmeliet, Peter, Tipping, Peter G.
Publicado 1997

Mutations in the Control of Virulence Sensor Gene from Streptococcus pyogenes after Infection in Mice Lead to Clonal Bacterial Variants with Altered Gene Regulatory Activity and Vi...

por Mayfield, Jeffrey A., Liang, Zhong, Agrahari, Garima, Lee, Shaun W., Donahue, Deborah L., Ploplis, Victoria A., Castellino, Francis J.
Publicado 2014

Neutralization of Streptolysin S-Dependent and Independent Inflammatory Cytokine IL-1β Activity Reduces Pathology During Early Group A Streptococcal Skin Infection

por Flaherty, Rebecca A., Donahue, Deborah L., Carothers, Katelyn E., Ross, Jessica N., Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Publicado 2018

Plasminogen Deficiency Significantly Reduces Vascular Wall Disease in a Murine Model of Type IIa Hypercholesterolemia

por Iwaki, Takayuki, Arakawa, Tomohiro, Sandoval-Cooper, Mayra J., Smith, Denise L., Donahue, Deborah, Ploplis, Victoria A., Umemura, Kazuo, Castellino, Francis J.
Publicado 2021

Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection

por Hammers, Daniel E., Donahue, Deborah L., Tucker, Zachary D., Ashfeld, Brandon L., Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Publicado 2022

Evolution of Streptococcus pyogenes has maximized the efficiency of the Sortase A cleavage motif for cell wall transpeptidation

por Readnour, Bradley M., Ayinuola, Yetunde A., Russo, Brady T., Liang, Zhong, Lee, Shaun W., Ploplis, Victoria A., Fischetti, Vincent A., Castellino, Francis J.
Publicado 2022

The Streptococcal Protease SpeB Antagonizes the Biofilms of the Human Pathogen Staphylococcus aureus USA300 through Cleavage of the Staphylococcal SdrC Protein

por Carothers, Katelyn E., Liang, Zhong, Mayfield, Jeffrey, Donahue, Deborah L., Lee, Mijoon, Boggess, Bill, Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Publicado 2020