Polymer Uncrossing and Knotting in Protein Folding, and Their Role in Minimal Folding Pathways

por Mohazab, Ali R., Plotkin, Steven S.
Publicado 2013

Passive immunotherapies targeting Aβ and tau in Alzheimer's disease

por Plotkin, Steven S., Cashman, Neil R.
Publicado 2020

Rationally Designed Chimeric Antibodies for COVID-19 and Future Coronavirus Variants

por Hsueh, Ching-chung, Plotkin, Steven S.
Publicado 2021

As Simple As Possible, but Not Simpler: Exploring the Fidelity of Coarse-Grained Protein Models for Simulated Force Spectroscopy

por Habibi, Mona, Rottler, Jörg, Plotkin, Steven S.
Publicado 2016

Emerging Developments in Targeting Proteotoxicity in Neurodegenerative Diseases

por McAlary, Luke, Plotkin, Steven S., Cashman, Neil R.
Publicado 2019

Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

por McAlary, Luke, Plotkin, Steven S., Yerbury, Justin J., Cashman, Neil R.
Publicado 2019

Corrigendum: Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

por McAlary, Luke, Plotkin, Steven S., Yerbury, Justin J., Cashman, Neil R.
Publicado 2020

A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria

por Peng, Xubiao, Gibbs, Ebrima, Silverman, Judith M, Cashman, Neil R, Plotkin, Steven S
Publicado 2021

First Principles Calculation of Protein–Protein Dimer Affinities of ALS-Associated SOD1 Mutants

por Hsueh, Shawn C. C., Nijland, Mark, Peng, Xubiao, Hilton, Benjamin, Plotkin, Steven S.
Publicado 2022

Optimizing Epitope Conformational Ensembles Using α-Synuclein Cyclic Peptide “Glycindel” Scaffolds: A Customized Immunogen Method for Generating Oligomer-Selective Antibodies for P...

por Hsueh, Shawn C. C., Aina, Adekunle, Roman, Andrei Yu., Cashman, Neil R., Peng, Xubiao, Plotkin, Steven S.
Publicado 2022

Purification and Structural Characterization of Aggregation-Prone Human TDP-43 Involved in Neurodegenerative Diseases

por Wright, Gareth S.A., Watanabe, Tatiana F., Amporndanai, Kangsa, Plotkin, Steven S., Cashman, Neil R., Antonyuk, Svetlana V., Hasnain, S. Samar
Publicado 2020

Assessment of protein inclusions in cultured cells using automated image analysis

por McAlary, Luke, Shephard, Victoria K., Sher, Mine, Rice, Lauren J., Yerbury, Justin J., Cashman, Neil R., Plotkin, Steven S.
Publicado 2022

A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer’s Disease

por Gibbs, Ebrima, Silverman, Judith M., Zhao, Beibei, Peng, Xubiao, Wang, Jing, Wellington, Cheryl L., Mackenzie, Ian R., Plotkin, Steven S., Kaplan, Johanne M., Cashman, Neil R.
Publicado 2019

Rational Generation of Monoclonal Antibodies Selective for Pathogenic Forms of Alpha-Synuclein

por Gibbs, Ebrima, Zhao, Beibei, Roman, Andrei, Plotkin, Steven S., Peng, Xubiao, Hsueh, Shawn C. C., Aina, Adekunle, Wang, Jing, Shyu, Clay, Yip, Calvin K., Nam, Sung-Eun, Kaplan, Johanne M., Cashman, Neil R.
Publicado 2022

Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells

por Pataer, Apar, Ozpolat, Bulent, Shao, RuPing, Cashman, Neil R., Plotkin, Steven S., Samuel, Charles E., Lin, Steven H., Kabil, Nashwa N., Wang, Jing, Majidi, Mourad, Fang, Bingliang, Roth, Jack A., Vaporciyan, Ara A., Wistuba, Ignacio I., Hung, Mien-Chie, Swisher, Stephen G.
Publicado 2019