Liver‐Targeted Toll‐Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus

por Korolowizc, Kyle E., Li, Bin, Huang, Xu, Yon, Changsuek, Rodrigo, Evelyn, Corpuz, Manny, Plouffe, David M., Kallakury, Bhaskar V., Suresh, Manasa, Wu, Tom Y.‐H., Miller, Andrew T., Menne, Stephan
Publicado 2019

A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor

por Nam, Tae-gyu, McNamara, Case W., Bopp, Selina, Dharia, Neekesh V., Meister, Stephan, Bonamy, Ghislain M. C., Plouffe, David M., Kato, Nobutaka, McCormack, Susan, Bursulaya, Badry, Ke, Hangjun, Vaidya, Akhil B., Schultz, Peter G., Winzeler, Elizabeth A.
Publicado 2011

Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials

por Abraham, Matthew, Gagaring, Kerstin, Martino, Marisa L., Vanaerschot, Manu, Plouffe, David M., Calla, Jaeson, Godinez-Macias, Karla P., Du, Alan Y., Wree, Melanie, Antonova-Koch, Yevgeniya, Eribez, Korina, Luth, Madeline R., Ottilie, Sabine, Fidock, David A., McNamara, Case W., Winzeler, Elizabeth A.
Publicado 2020

High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission

por Plouffe, David M., Wree, Melanie, Du, Alan Y., Meister, Stephan, Li, Fengwu, Patra, Kailash, Lubar, Aristea, Okitsu, Shinji L., Flannery, Erika L., Kato, Nobutaka, Tanaseichuk, Olga, Comer, Eamon, Zhou, Bin, Kuhen, Kelli, Zhou, Yingyao, Leroy, Didier, Schreiber, Stuart L., Scherer, Christina A., Vinetz, Joseph, Winzeler, Elizabeth A.
Publicado 2016

Selective and Specific Inhibition of the Plasmodium falciparum Lysyl-tRNA Synthetase by the Fungal Secondary Metabolite Cladosporin

por Hoepfner, Dominic, McNamara, Case W., Lim, Chek Shik, Studer, Christian, Riedl, Ralph, Aust, Thomas, McCormack, Susan L., Plouffe, David M., Meister, Stephan, Schuierer, Sven, Plikat, Uwe, Hartmann, Nicole, Staedtler, Frank, Cotesta, Simona, Schmitt, Esther K., Petersen, Frank, Supek, Frantisek, Glynne, Richard J., Tallarico, John A., Porter, Jeffrey A., Fishman, Mark C., Bodenreider, Christophe, Diagana, Thierry T., Movva, N. Rao, Winzeler, Elizabeth A.
Publicado 2012

KAI407, a Potent Non-8-Aminoquinoline Compound That Kills Plasmodium cynomolgi Early Dormant Liver Stage Parasites In Vitro

por Zeeman, Anne-Marie, van Amsterdam, Sandra M., McNamara, Case W., Voorberg-van der Wel, Annemarie, Klooster, Els J., van den Berg, Alexander, Remarque, Edmond J., Plouffe, David M., van Gemert, Geert-Jan, Luty, Adrian, Sauerwein, Robert, Gagaring, Kerstin, Borboa, Rachel, Chen, Zhong, Kuhen, Kelli, Glynne, Richard J., Chatterjee, Arnab K., Nagle, Advait, Roland, Jason, Winzeler, Elizabeth A., Leroy, Didier, Campo, Brice, Diagana, Thierry T., Yeung, Bryan K. S., Thomas, Alan W., Kocken, Clemens H. M.
Publicado 2014

Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria

por McNamara, Case W, Lee, Marcus CS, Lim, Chek Shik, Lim, Siau Hoi, Roland, Jason, Simon, Oliver, Yeung, Bryan KS, Chatterjee, Arnab K, McCormack, Susan L, Manary, Micah J, Zeeman, Anne-Marie, Dechering, Koen J, Kumar, TR Santha, Henrich, Philipp P, Gagaring, Kerstin, Ibanez, Maureen, Kato, Nobutaka, Kuhen, Kelli L, Fischli, Christoph, Nagle, Advait, Rottmann, Matthias, Plouffe, David M, Bursulaya, Badry, Meister, Stephan, Rameh, Lucia, Trappe, Joerg, Haasen, Dorothea, Timmerman, Martijn, Sauerwein, Robert W, Suwanarusk, Rossarin, Russell, Bruce, Renia, Laurent, Nosten, Francois, Tully, David C, Kocken, Clemens HM, Glynne, Richard J, Bodenreider, Christophe, Fidock, David A, Diagana, Thierry T, Winzeler, Elizabeth A
Publicado 2013

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

por Van Voorhis, Wesley C., Adams, John H., Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H., Alano, Pietro, Alday, Aintzane, Alemán Resto, Yesmalie, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T., Avery, Simon V., Avery, Vicky M., Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bhatia, Sangeeta, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E., Boyom, Fabrice F., Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R., Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Belen Cassera, Maria, Chih-Chien Cheng, Ken, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L., Colón-López, Daisy D., Corbett, Yolanda, Crowther, Gregory J., Cowan, Noemi, D’Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L., Du, Alan Y., Duffy, Sandra, Abd El-Salam El-Sayed, Shimaa, Ferdig, Michael T., Fernández Robledo, José A., Fidock, David A., Florent, Isabelle, Fokou, Patrick V. T., Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M., Guha, Rajarshi, Guiguemde, W. Armand, Gural, Nil, Guy, R. Kiplin, Hansen, Michael A. E., Hanson, Kirsten K., Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B., Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A., Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T., Jiang, Rays H. Y., Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P., Kyle, Dennis E., Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M., Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I., Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis, Mancama, Dalu, Mansour, Nuha R., March, Sandra, McGowan, Sheena, Medina Vera, Iset, Meister, Stephan, Mercer, Luke, Mestres, Jordi, Mfopa, Alvine N., Misra, Raj N., Moon, Seunghyun, Moore, John P., Morais Rodrigues da Costa, Francielly, Müller, Joachim, Muriana, Arantza, Nakazawa Hewitt, Stephen, Nare, Bakela, Nathan, Carl, Narraidoo, Nathalie, Nawaratna, Sujeevi, Ojo, Kayode K., Ortiz, Diana, Panic, Gordana, Papadatos, George, Parapini, Silvia, Patra, Kailash, Pham, Ngoc, Prats, Sarah, Plouffe, David M., Poulsen, Sally-Ann, Pradhan, Anupam, Quevedo, Celia, Quinn, Ronald J., Rice, Christopher A., Abdo Rizk, Mohamed, Ruecker, Andrea, St. Onge, Robert, Salgado Ferreira, Rafaela, Samra, Jasmeet, Robinett, Natalie G., Schlecht, Ulrich, Schmitt, Marjorie, Silva Villela, Filipe, Silvestrini, Francesco, Sinden, Robert, Smith, Dennis A., Soldati, Thierry, Spitzmüller, Andreas, Stamm, Serge Maximilian, Sullivan, David J., Sullivan, William, Suresh, Sundari, Suzuki, Brian M., Suzuki, Yo, Swamidass, S. Joshua, Taramelli, Donatella, Tchokouaha, Lauve R. Y., Theron, Anjo, Thomas, David, Tonissen, Kathryn F., Townson, Simon, Tripathi, Abhai K., Trofimov, Valentin, Udenze, Kenneth O., Ullah, Imran, Vallieres, Cindy, Vigil, Edgar, Vinetz, Joseph M., Voong Vinh, Phat, Vu, Hoan, Watanabe, Nao-aki, Weatherby, Kate, White, Pamela M., Wilks, Andrew F., Winzeler, Elizabeth A., Wojcik, Edward, Wree, Melanie, Wu, Wesley, Yokoyama, Naoaki, Zollo, Paul H. A., Abla, Nada, Blasco, Benjamin, Burrows, Jeremy, Laleu, Benoît, Leroy, Didier, Spangenberg, Thomas, Wells, Timothy, Willis, Paul A.
Publicado 2016