Critical roles of phosphoinositides and NF2 in Hippo pathway regulation

por Hong, Audrey W., Meng, Zhipeng, Plouffe, Steven W., Lin, Zhijie, Zhang, Mingjie, Guan, Kun-Liang
Publicado 2020

Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth

por Koo, Ja Hyun, Plouffe, Steven W., Meng, Zhipeng, Lee, Da-Hye, Yang, Di, Lim, Dae-Sik, Wang, Cun-Yu, Guan, Kun-Liang
Publicado 2020

Differential regulation of mTORC1 by leucine and glutamine

por Jewell, Jenna L., Kim, Young Chul, Russell, Ryan C., Yu, Fa-Xing, Park, Hyun Woo, Plouffe, Steven W., Tagliabracci, Vincent S., Guan, Kun-Liang
Publicado 2015

Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation

por Lin, Kimberly C., Moroishi, Toshiro, Meng, Zhipeng, Jeong, Han-Sol, Plouffe, Steven W., Sekido, Yoshitaka, Han, Jiahuai, Park, Hyun Woo, Guan, Kun-Liang
Publicado 2017

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

por Moroishi, Toshiro, Park, Hyun Woo, Qin, Baodong, Chen, Qian, Meng, Zhipeng, Plouffe, Steven W., Taniguchi, Koji, Yu, Fa-Xing, Karin, Michael, Pan, Duojia, Guan, Kun-Liang
Publicado 2015

Co‐occurrence of BAP1 and SF3B1 mutations in uveal melanoma induces cellular senescence

por Yu, Le, Zhou, Dan, Zhang, Guiming, Ren, Zhonglu, Luo, Xin, Liu, Peng, Plouffe, Steven W., Meng, Zhipeng, Moroishi, Toshiro, Li, Yilei, Zhang, Yiyue, Brown, Joan Heller, Liu, Shuwen, Guan, Kun‐Liang
Publicado 2021

Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation

por Meng, Fansen, Zhou, Ruyuan, Wu, Shiying, Zhang, Qian, Jin, Qiuheng, Zhou, Yao, Plouffe, Steven W., Liu, Shengduo, Song, Hai, Xia, Zongping, Zhao, Bin, Ye, Sheng, Feng, Xin-Hua, Guan, Kun-Liang, Zou, Jian, Xu, Pinglong
Publicado 2016

Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade

por Zhang, Qian, Meng, Fansen, Chen, Shasha, Plouffe, Steven W., Wu, Shiying, Liu, Shengduo, Li, Xinran, Zhou, Ruyuan, Wang, Junxian, Zhao, Bin, Liu, Jianming, Qin, Jun, Zou, Jian, Feng, Xin-Hua, Guan, Kun-Liang, Xu, Pinglong
Publicado 2017

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity

por Yu, Olivia M, Benitez, Jorge A, Plouffe, Steven W, Ryback, Daniel, Klein, Andrea, Smith, Jeff, Greenbaum, Jason, Delatte, Benjamin, Rao, Anjana, Guan, Kun-Liang, Furnari, Frank B, Chaim, Olga Meiri, Miyamoto, Shigeki, Brown, Joan Heller
Publicado 2018

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

por Meng, Zhipeng, Moroishi, Toshiro, Mottier-Pavie, Violaine, Plouffe, Steven W., Hansen, Carsten G., Hong, Audrey W., Park, Hyun Woo, Mo, Jung-Soon, Lu, Wenqi, Lu, Shicong, Flores, Fabian, Yu, Fa-Xing, Halder, Georg, Guan, Kun-Liang
Publicado 2015

RAP2 Mediates Mechano-responses of Hippo Pathway

por Meng, Zhipeng, Qiu, Yunjiang, Lin, Kimberly C., Kumar, Aditya, Placone, Jesse K., Fang, Cao, Wang, Kuei-Chun, Lu, Shicong, Pan, Margaret, Hong, Audrey W., Moroishi, Toshiro, Luo, Min, Plouffe, Steven W., Diao, Yarui, Ye, Zhen, Park, Hyun Woo, Wang, Xiaoqiong, Yu, Fa-Xing, Chien, Shu, Wang, Cun-Yu, Ren, Bing, Engler, Adam J., Guan, Kun-Liang
Publicado 2018