Structure-Driven Design of Radionuclide Tracers for Non-Invasive Imaging of uPAR and Targeted Radiotherapy. The Tale of a Synthetic Peptide Antagonist

por Ploug, Michael
Publicado 2013

Targeting the Urokinase-Type Plasminogen Activator Receptor (uPAR) in Human Diseases With a View to Non-invasive Imaging and Therapeutic Intervention

por Leth, Julie Maja, Ploug, Michael
Publicado 2021

The Urokinase Receptor (uPAR) as a “Trojan Horse” in Targeted Cancer Therapy: Challenges and Opportunities

por Metrangolo, Virginia, Ploug, Michael, Engelholm, Lars H.
Publicado 2021

Peptide-Based Optical uPAR Imaging for Surgery: In Vivo Testing of ICG-Glu-Glu-AE105

por Juhl, Karina, Christensen, Anders, Persson, Morten, Ploug, Michael, Kjaer, Andreas
Publicado 2016

Expression of C4.4A in an In Vitro Human Tissue-Engineered Skin Model

por Jacobsen, Benedikte, Larouche, Danielle, Rochette-Drouin, Olivier, Ploug, Michael, Germain, Lucie
Publicado 2017

ANGPTL4 sensitizes lipoprotein lipase to PCSK3 cleavage by catalyzing its unfolding

por Lund Winther, Anne-Marie, Kumari, Anni, Young, Stephen G., Ploug, Michael
Publicado 2021

The Importance of Lipoprotein Lipase Regulation in Atherosclerosis

por Kumari, Anni, Kristensen, Kristian K., Ploug, Michael, Winther, Anne-Marie Lund
Publicado 2021

Improved PET Imaging of uPAR Expression Using new (64)Cu-labeled Cross-Bridged Peptide Ligands: Comparative in vitro and in vivo Studies

por Persson, Morten, Hosseini, Masood, Madsen, Jacob, Jørgensen, Thomas J. D., Jensen, Knud J, Kjaer, Andreas, Ploug, Michael
Publicado 2013

Neutralisation of uPA with a Monoclonal Antibody Reduces Plasmin Formation and Delays Skin Wound Healing in tPA-Deficient Mice

por Jögi, Annika, Rønø, Birgitte, Lund, Ida K., Nielsen, Boye S., Ploug, Michael, Høyer-Hansen, Gunilla, Rømer, John, Lund, Leif R.
Publicado 2010

Disorder in a two-domain neuronal Ca(2+)-binding protein regulates domain stability and dynamics using ligand mimicry

por Staby, Lasse, Kemplen, Katherine R., Stein, Amelie, Ploug, Michael, Clarke, Jane, Skriver, Karen, Heidarsson, Pétur O., Kragelund, Birthe B.
Publicado 2020

A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism

por Young, Stephen G., Song, Wenxin, Yang, Ye, Birrane, Gabriel, Jiang, Haibo, Beigneux, Anne P., Ploug, Michael, Fong, Loren G.
Publicado 2022

Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase

por Kumari, Anni, Grønnemose, Anne Louise, Kristensen, Kristian K., Winther, Anne-Marie L., Young, Stephen G., Jørgensen, Thomas J. D., Ploug, Michael
Publicado 2023

Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography

por Zhao, Baoyu, Gandhi, Sonu, Yuan, Cai, Luo, Zhipu, Li, Rui, Gårdsvoll, Henrik, de Lorenzi, Valentina, Sidenius, Nicolai, Huang, Mingdong, Ploug, Michael
Publicado 2015

The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding

por Mysling, Simon, Kristensen, Kristian Kølby, Larsson, Mikael, Kovrov, Oleg, Bensadouen, André, Jørgensen, Thomas JD, Olivecrona, Gunilla, Young, Stephen G, Ploug, Michael
Publicado 2016

Origin and diversification of the plasminogen activation system among chordates

por Chana-Muñoz, Andrés, Jendroszek, Agnieszka, Sønnichsen, Malene, Wang, Tobias, Ploug, Michael, Jensen, Jan K., Andreasen, Peter A., Bendixen, Christian, Panitz, Frank
Publicado 2019

Evolution and Medical Significance of LU Domain−Containing Proteins

por Leth, Julie Maja, Leth-Espensen, Katrine Zinck, Kristensen, Kristian Kølby, Kumari, Anni, Lund Winther, Anne-Marie, Young, Stephen G., Ploug, Michael
Publicado 2019

GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity

por Kristensen, Kristian Kølby, Leth-Espensen, Katrine Zinck, Kumari, Anni, Grønnemose, Anne Louise, Lund-Winther, Anne-Marie, Young, Stephen G., Ploug, Michael
Publicado 2021

Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/α-neurotoxin Domain

por Jiang, Yunbin, Lin, Lin, Chen, Shanli, Jiang, Longguang, Kriegbaum, Mette C., Gårdsvoll, Henrik, Hansen, Line V., Li, Jinyu, Ploug, Michael, Yuan, Cai, Huang, Mingdong
Publicado 2020

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain

por Mysling, Simon, Kristensen, Kristian Kølby, Larsson, Mikael, Beigneux, Anne P, Gårdsvoll, Henrik, Fong, Loren G, Bensadouen, André, Jørgensen, Thomas JD, Young, Stephen G, Ploug, Michael
Publicado 2016

Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication

por Klimovskaia, Ilnaz M, Young, Clifford, Strømme, Caroline B, Menard, Patrice, Jasencakova, Zuzana, Mejlvang, Jakob, Ask, Katrine, Ploug, Michael, Nielsen, Michael L, Jensen, Ole N, Groth, Anja
Publicado 2014