Increased stromal PFKFB3-mediated glycolysis in inflammatory bowel disease contributes to intestinal inflammation

por Zhou, Zhou, Plug, Leonie G., Patente, Thiago A., de Jonge-Muller, Eveline S. M., Elmagd, Amir Abou, van der Meulen-de Jong, Andrea E., Everts, Bart, Barnhoorn, Marieke C., Hawinkels, Lukas J. A. C.
Publicado 2022

Cytokine Mixtures Mimicking the Local Milieu in Patients with Inflammatory Bowel Disease Impact Phenotype and Function of Mesenchymal Stromal Cells

por Barnhoorn, Marieke C, van der Meulen-de Jong, Andrea E, Schrama, Ellen C L M, Plug, Leonie G, Verspaget, Hein W, Fibbe, Willem E, van Pel, Melissa, Hawinkels, Lukas J A C, Schepers, Koen
Publicado 2022

Local administration of mesenchymal stromal cells is safe and modulates the immune compartment in ulcerative proctitis

por Ouboter, Laura F., Barnhoorn, Marieke C., Verspaget, Hein W., Plug, Leonie, Pool, Emma S., Szuhai, Karoly, Hawinkels, Lukas J.A.C., van Pel, Melissa, Zwaginga, Jaap Jan, Roelen, Dave, Koning, Frits, Pascutti, M. Fernanda, van der Meulen – de Jong, Andrea E.
Publicado 2023

Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S

por Harryvan, Tom J, Visser, Marten, de Bruin, Linda, Plug, Léonie, Griffioen, Lisa, Mulder, Arend, van Veelen, Peter A, van der Heden van Noort, Gerbrand J, Jongsma, Marlieke LM, Meeuwsen, Miranda H, Wiertz, Emmanuel JHJ, Santegoets, Saskia J, Hardwick, James CH, Van Hall, Thorbald, Neefjes, Jacques, Van der Burg, Sjoerd H, Hawinkels, Lukas JAC, Verdegaal, Els ME
Publicado 2022