PINK1: From Parkinson’s disease to mitophagy and back again

por O’Callaghan, Benjamin, Hardy, John, Plun-Favreau, Helene
Publicado 2023

PINK1 function in health and disease

por Deas, Emma, Plun-Favreau, Helene, Wood, Nicholas W
Publicado 2009

Mitophagy and Parkinson's disease: The PINK1–parkin link()

por Deas, Emma, Wood, Nicholas W., Plun-Favreau, Hélène
Publicado 2011

Pierre D. and the first photographs of Parkinson's disease

por Lewis, Patrick A., Plun‐Favreau, Helene, Rowley, Mark, Spillane, Jennifer
Publicado 2020

Vesicle trafficking and pathways to neurodegeneration

por Blackstone, Craig, Elwood, Fiona, Plun-Favreau, Helene, Lewis, Patrick A.
Publicado 2021

Cancer and Neurodegeneration: Between the Devil and the Deep Blue Sea

por Plun-Favreau, Hélène, Lewis, Patrick A., Hardy, John, Martins, L. Miguel, Wood, Nicholas W.
Publicado 2010

Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation

por Delgado-Camprubi, Marta, Esteras, Noemi, Soutar, Marc PM, Plun-Favreau, Helene, Abramov, Andrey Y
Publicado 2017

Deficiency of Parkinson’s disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation

por Delgado-Camprubi, Marta, Esteras, Noemi, Soutar, Marc PM, Plun-Favreau, Helene, Abramov, Andrey Y
Publicado 2017

Exploring autophagy with Gene Ontology

por Denny, Paul, Feuermann, Marc, Hill, David P., Lovering, Ruth C., Plun-Favreau, Helene, Roncaglia, Paola
Publicado 2018

Culprit or Bystander: Defective Mitophagy in Alzheimer’s Disease

por Xie, Chenglong, Aman, Yahyah, Adriaanse, Bryan A., Cader, M. Zameel, Plun-Favreau, Hélène, Xiao, Jian, Fang, Evandro F.
Publicado 2020

Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to OPA1 mutations

por Lynch, David S., Loh, Samantha H.Y., Harley, Jasmine, Noyce, Alastair J., Martins, L. Miguel, Wood, Nicholas W., Houlden, Henry, Plun-Favreau, Helene
Publicado 2017

The role of SQSTM1 (p62) in mitochondrial function and clearance in human cortical neurons

por Poon, Anna, Saini, Harpreet, Sethi, Siddharth, O'Sullivan, Gregory A., Plun-Favreau, Hélène, Wray, Selina, Dawson, Lee A., McCarthy, James M.
Publicado 2021

The non-specific lethal complex regulates genes and pathways genetically linked to Parkinson’s disease

por Hicks, Amy R, Reynolds, Regina H, O’Callaghan, Benjamin, García-Ruiz, Sonia, Gil-Martínez, Ana Luisa, Botía, Juan, Plun-Favreau, Hélène, Ryten, Mina
Publicado 2023

Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin

por Tain, Luke S., Chowdhury, Ruhena B., Tao, Ran N., Plun-Favreau, Helene, Moisoi, Nicoleta, Martins, L. Miguel, Downward, Julian, Whitworth, Alexander J., Tapon, Nicolas
Publicado 2009

Inhibition of LRRK2 kinase activity stimulates macroautophagy()

por Manzoni, Claudia, Mamais, Adamantios, Dihanich, Sybille, Abeti, Rosella, Soutar, Marc P.M., Plun-Favreau, Helene, Giunti, Paola, Tooze, Sharon A., Bandopadhyay, Rina, Lewis, Patrick A.
Publicado 2013

Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase

por Birsa, Nicol, Norkett, Rosalind, Wauer, Tobias, Mevissen, Tycho E. T., Wu, Hsiu-Chuan, Foltynie, Thomas, Bhatia, Kailash, Hirst, Warren D., Komander, David, Plun-Favreau, Helene, Kittler, Josef T.
Publicado 2014

mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1

por Manzoni, Claudia, Mamais, Adamantios, Roosen, Dorien A., Dihanich, Sybille, Soutar, Marc P. M., Plun-Favreau, Helene, Bandopadhyay, Rina, Hardy, John, Tooze, Sharon A., Cookson, Mark R., Lewis, Patrick A.
Publicado 2016

PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death

por Gandhi, Sonia, Wood-Kaczmar, Alison, Yao, Zhi, Plun-Favreau, Helene, Deas, Emma, Klupsch, Kristina, Downward, Julian, Latchman, David S., Tabrizi, Sarah J., Wood, Nicholas W., Duchen, Michael R., Abramov, Andrey Y.
Publicado 2009

mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition

por Manzoni, Claudia, Mamais, Adamantios, Dihanich, Sybille, Soutar, Marc P.M., Plun-Favreau, Helene, Bandopadhyay, Rina, Abeti, Rosella, Giunti, Paola, Hardy, John, R. Cookson, Mark, Tooze, Sharon A., Lewis, Patrick A.
Publicado 2018

AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons

por Soutar, Marc P. M., Kempthorne, Liam, Miyakawa, Shuichi, Annuario, Emily, Melandri, Daniela, Harley, Jasmine, O’Sullivan, Gregory A., Wray, Selina, Hancock, David C., Cookson, Mark R., Downward, Julian, Carlton, Mark, Plun-Favreau, Hélène
Publicado 2018