Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer

por Uo, Takuma, Sprenger, Cynthia C., Plymate, Stephen R.
Publicado 2020

Starving lethal prostate cancer by targeting heat shock proteins and glycolytic enzymes

por Plymate, Stephen R., Sprenger, Cynthia, Haffner, Michael C.
Publicado 2022

Intracrine androgen biosynthesis and drug resistance

por Penning, Trevor M., Asangani, Irfan A., Sprenger, Cynthia, Plymate, Stephen
Publicado 2020

AR-V7 biomarker testing for primary prostate cancer: The ongoing challenge of analytical validation and clinical qualification

por Sowalsky, Adam G., Sharp, Adam, Trostel, Shana Y., de Bono, Johann S., Plymate, Stephen R.
Publicado 2020

Druggable Metabolic Vulnerabilities Are Exposed and Masked during Progression to Castration Resistant Prostate Cancer

por Choi, Stephen Y. C., Ribeiro, Caroline Fidalgo, Wang, Yuzhuo, Loda, Massimo, Plymate, Stephen R., Uo, Takuma
Publicado 2022

The Effects of Aging on the Molecular and Cellular Composition of the Prostate Microenvironment

por Bianchi-Frias, Daniella, Vakar-Lopez, Funda, Coleman, Ilsa M., Plymate, Stephen R., Reed, May J., Nelson, Peter S.
Publicado 2010

MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligand

por Liu, Gang, Sprenger, Cynthia, Wu, Pin-Jou, Sun, Shihua, Uo, Takuma, Haugk, Kathleen, Epilepsia, Kathryn Soriano, Plymate, Stephen
Publicado 2014

Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions

por Mohammad, Osama S., Nyquist, Michael D., Schweizer, Michael T., Balk, Stephen P., Corey, Eva, Plymate, Stephen, Nelson, Peter S., Mostaghel, Elahe A.
Publicado 2017

IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR

por Rojas, Andres, Liu, Gang, Coleman, Ilsa, Nelson, Peter S., Zhang, Miqin, Dash, Rupesh, Fisher, Paul B, Plymate, Stephen R., Wu, Jennifer D.
Publicado 2011

Androgen Receptor Variants Occur Frequently in Castration Resistant Prostate Cancer Metastases

por Zhang, Xiaotun, Morrissey, Colm, Sun, Shihua, Ketchandji, Melanie, Nelson, Peter S., True, Lawrence D., Vakar-Lopez, Funda, Vessella, Robert L., Plymate, Stephen R.
Publicado 2011

Prostate Stromal Cells Express the Progesterone Receptor to Control Cancer Cell Mobility

por Yu, Yue, Lee, Jennifer Suehyun, Xie, Ning, Li, Estelle, Hurtado-Coll, Antonio, Fazli, Ladan, Cox, Michael, Plymate, Stephen, Gleave, Martin, Dong, Xuesen
Publicado 2014

Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors

por Gillis, Joanna L., Selth, Luke A., Centenera, Margaret M., Townley, Scott L., Sun, Shihua, Plymate, Stephen R., Tilley, Wayne D., Butler, Lisa M.
Publicado 2013

Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer

por Asangani, Irfan, Blair, Ian A., Van Duyne, Gregory, Hilser, Vincent J., Moiseenkova-Bell, Vera, Plymate, Stephen, Sprenger, Cynthia, Wand, A. Joshua, Penning, Trevor M.
Publicado 2021

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy

por Cao, Bo, Qi, Yanfeng, Zhang, Guanyi, Xu, Duo, Zhan, Yang, Alvarez, Xavier, Guo, Zhiyong, Fu, Xueqi, Plymate, Stephen R., Sartor, Oliver, Zhang, Haitao, Dong, Yan
Publicado 2014

Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Pro...

por Welti, Jonathan, Rodrigues, Daniel Nava, Sharp, Adam, Sun, Shihua, Lorente, David, Riisnaes, Ruth, Figueiredo, Ines, Zafeiriou, Zafeiris, Rescigno, Pasquale, de Bono, Johann S., Plymate, Stephen R.
Publicado 2016

ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer

por Bae, Song Yi, Bergom, Hannah E., Day, Abderrahman, Greene, Joseph T., Sychev, Zoi E., Larson, Gabrianne, Corey, Eva, Plymate, Stephen R., Freedman, Tanya S., Hwang, Justin H., Drake, Justin M.
Publicado 2023

Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor through cMYC Repression and Recruitment of the DREAM Complex

por Nyquist, Michael D., Coleman, Ilsa M., Lucas, Jared M., Li, Dapei, Hanratty, Brian, Meade, Hannah, Mostaghel, Elahe A., Plymate, Stephen R., Corey, Eva, Haffner, Michael C., Nelson, Peter S.
Publicado 2023

Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts

por Sychev, Zoi E., Day, Abderrahman, Bergom, Hannah E., Larson, Gabrianne, Ali, Atef, Ludwig, Megan, Boytim, Ella, Coleman, Ilsa, Corey, Eva, Plymate, Stephen R., Nelson, Peter S., Hwang, Justin H., Drake, Justin M.
Publicado 2023

A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer

por Schweizer, Michael T., Haugk, Kathleen, McKiernan, Jožefa S., Gulati, Roman, Cheng, Heather H., Maes, Jessica L., Dumpit, Ruth F., Nelson, Peter S., Montgomery, Bruce, McCune, Jeannine S., Plymate, Stephen R., Yu, Evan Y.
Publicado 2018

Correction: A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer

por Schweizer, Michael T., Haugk, Kathleen, McKiernan, Jožefa S., Gulati, Roman, Cheng, Heather H., Maes, Jessica L., Dumpit, Ruth F., Nelson, Peter S., Montgomery, Bruce, McCune, Jeannine S., Plymate, Stephen R., Yu, Evan Y.
Publicado 2018