The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour

por Pocklington, Andrew J, Cumiskey, Mark, Armstrong, J Douglas, Grant, Seth G N
Publicado 2006

Gender differences in CNV burden do not confound schizophrenia CNV associations

por Han, Jun, Walters, James T. R., Kirov, George, Pocklington, Andrew, Escott-Price, Valentina, Owen, Michael J., Holmans, Peter, O’Donovan, Michael C., Rees, Elliott
Publicado 2016

Biological Overlap of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder: Evidence From Copy Number Variants

por Martin, Joanna, Cooper, Miriam, Hamshere, Marian L., Pocklington, Andrew, Scherer, Stephen W., Kent, Lindsey, Gill, Michael, Owen, Michael J., Williams, Nigel, O'Donovan, Michael C., Thapar, Anita, Holmans, Peter
Publicado 2014

Predictive modeling of schizophrenia from genomic data: Comparison of polygenic risk score with kernel support vector machines approach

por Vivian‐Griffiths, Timothy, Baker, Emily, Schmidt, Karl M., Bracher‐Smith, Matthew, Walters, James, Artemiou, Andreas, Holmans, Peter, O'Donovan, Michael C., Owen, Michael J., Pocklington, Andrew, Escott‐Price, Valentina
Publicado 2018

Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics

por Pain, Oliver, Pocklington, Andrew J., Holmans, Peter A., Bray, Nicholas J., O’Brien, Heath E., Hall, Lynsey S., Pardiñas, Antonio F., O’Donovan, Michael C., Owen, Michael J., Anney, Richard
Publicado 2019

Dynamic expression of genes associated with schizophrenia and bipolar disorder across development

por Clifton, Nicholas E., Hannon, Eilís, Harwood, Janet C., Di Florio, Arianna, Thomas, Kerrie L., Holmans, Peter A., Walters, James T. R., O’Donovan, Michael C., Owen, Michael J., Pocklington, Andrew J., Hall, Jeremy
Publicado 2019

A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia

por Hall, Lynsey S, Medway, Christopher W, Pain, Oliver, Pardiñas, Antonio F, Rees, Elliott G, Escott-Price, Valentina, Pocklington, Andrew, Bray, Nicholas J, Holmans, Peter A, Walters, James T R, Owen, Michael J, O’Donovan, Michael C
Publicado 2020

Genetic association of FMRP targets with psychiatric disorders

por Clifton, Nicholas E., Rees, Elliott, Holmans, Peter A., Pardiñas, Antonio F., Harwood, Janet C., Di Florio, Arianna, Kirov, George, Walters, James T. R., O’Donovan, Michael C., Owen, Michael J., Hall, Jeremy, Pocklington, Andrew J.
Publicado 2020

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

por Pocklington, Andrew J., Rees, Elliott, Walters, James T.R., Han, Jun, Kavanagh, David H., Chambert, Kimberly D., Holmans, Peter, Moran, Jennifer L., McCarroll, Steven A., Kirov, George, O’Donovan, Michael C., Owen, Michael J.
Publicado 2015

Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort

por Grama, Steluta, Willcocks, Isabella, Hubert, John J., Pardiñas, Antonio F., Legge, Sophie E., Bracher-Smith, Matthew, Menzies, Georgina E., Hall, Lynsey S., Pocklington, Andrew J., Anney, Richard J. L., Bray, Nicholas J., Escott-Price, Valentina, Caseras, Xavier
Publicado 2020

Structural and Functional Neuroimaging of Polygenic Risk for Schizophrenia: A Recall-by-Genotype–Based Approach

por Lancaster, Thomas M, Dimitriadis, Stavros L, Tansey, Katherine E, Perry, Gavin, Ihssen, Niklas, Jones, Derek K, Singh, Krish D, Holmans, Peter, Pocklington, Andrew, Davey Smith, George, Zammit, Stan, Hall, Jeremy, O’Donovan, Michael C, Owen, Michael J, Linden, David E
Publicado 2019

Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes

por Morgan, Sarah E., Seidlitz, Jakob, Whitaker, Kirstie J., Romero-Garcia, Rafael, Clifton, Nicholas E., Scarpazza, Cristina, van Amelsvoort, Therese, Marcelis, Machteld, van Os, Jim, Donohoe, Gary, Mothersill, David, Corvin, Aiden, Pocklington, Andrew, Raznahan, Armin, McGuire, Philip, Vértes, Petra E., Bullmore, Edward T.
Publicado 2019

Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis

por Rees, Elliott, Carrera, Noa, Morgan, Joanne, Hambridge, Kirsty, Escott-Price, Valentina, Pocklington, Andrew J., Richards, Alexander L., Pardiñas, Antonio F., McDonald, Colm, Donohoe, Gary, Morris, Derek W., Kenny, Elaine, Kelleher, Eric, Gill, Michael, Corvin, Aiden, Kirov, George, Walters, James T.R., Holmans, Peter, Owen, Michael J., O’Donovan, Michael C.
Publicado 2019

Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk var...

por Sanders, Bret, D’Andrea, Daniel, Collins, Mark O., Rees, Elliott, Steward, Tom G. J., Zhu, Ying, Chapman, Gareth, Legge, Sophie E., Pardiñas, Antonio F., Harwood, Adrian J., Gray, William P., O’Donovan, Michael C., Owen, Michael J., Errington, Adam C., Blake, Derek J., Whitcomb, Daniel J., Pocklington, Andrew J., Shin, Eunju
Publicado 2022

Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia

por Leonenko, Ganna, Richards, Alexander L., Walters, James T., Pocklington, Andrew, Chambert, Kimberly, Al Eissa, Mariam M., Sharp, Sally I., O'Brien, Niamh L., Curtis, David, Bass, Nicholas J., McQuillin, Andrew, Hultman, Christina, Moran, Jennifer L., McCarroll, Steven A., Sklar, Pamela, Neale, Benjamin M., Holmans, Peter A., Owen, Michael J., Sullivan, Patrick F., O'Donovan, Michael C.
Publicado 2017

De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia

por Rees, Elliott, Han, Jun, Morgan, Joanne, Carrera, Noa, Escott-Price, Valentina, Pocklington, Andrew J., Duffield, Madeleine, Hall, Lynsey, Legge, Sophie E., Pardiñas, Antonio F., Richards, Alexander L., Roth, Julian, Lezheiko, Tatyana, Kondratyev, Nikolay, Kaleda, Vasilii, Golimbet, Vera, Parellada, Mara, González-Peñas, Javier, Arango, Celso, Gawlik, Micha, Kirov, George, Walters, James T. R., Holmans, Peter, O’Donovan, Michael C., Owen, Michael J.
Publicado 2020

Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

por Fernández, Esperanza, Collins, Mark O., Frank, René A.W., Zhu, Fei, Kopanitsa, Maksym V., Nithianantharajah, Jess, Lemprière, Sarah A., Fricker, David, Elsegood, Kathryn A., McLaughlin, Catherine L., Croning, Mike D.R., Mclean, Colin, Armstrong, J. Douglas, Hill, W. David, Deary, Ian J., Cencelli, Giulia, Bagni, Claudia, Fromer, Menachem, Purcell, Shaun M., Pocklington, Andrew J., Choudhary, Jyoti S., Komiyama, Noboru H., Grant, Seth G.N.
Publicado 2017

Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development

por Phillips, Tom J., Scott, Hannah, Menassa, David A., Bignell, Ashleigh L., Sood, Aman, Morton, Jude S., Akagi, Takami, Azuma, Koki, Rogers, Mark F., Gilmore, Catherine E., Inman, Gareth J., Grant, Simon, Chung, Yealin, Aljunaidy, Mais M., Cooke, Christy-Lynn, Steinkraus, Bruno R., Pocklington, Andrew, Logan, Angela, Collett, Gavin P., Kemp, Helena, Holmans, Peter A., Murphy, Michael P., Fulga, Tudor A., Coney, Andrew M., Akashi, Mitsuru, Davidge, Sandra T., Case, C. Patrick
Publicado 2017

Clustered Coding Variants in the Glutamate Receptor Complexes of Individuals with Schizophrenia and Bipolar Disorder

por Frank, René A. W., McRae, Allan F., Pocklington, Andrew J., van de Lagemaat, Louie N., Navarro, Pau, Croning, Mike D. R., Komiyama, Noboru H., Bradley, Sophie J., Challiss, R. A. John, Armstrong, J. Douglas, Finn, Robert D., Malloy, Mary P., MacLean, Alan W., Harris, Sarah E., Starr, John M., Bhaskar, Sanjeev S., Howard, Eleanor K., Hunt, Sarah E., Coffey, Alison J., Ranganath, Venkatesh, Deloukas, Panos, Rogers, Jane, Muir, Walter J., Deary, Ian J., Blackwood, Douglas H., Visscher, Peter M., Grant, Seth G. N.
Publicado 2011

Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

por Jones, Lesley, Holmans, Peter A., Hamshere, Marian L., Harold, Denise, Moskvina, Valentina, Ivanov, Dobril, Pocklington, Andrew, Abraham, Richard, Hollingworth, Paul, Sims, Rebecca, Gerrish, Amy, Pahwa, Jaspreet Singh, Jones, Nicola, Stretton, Alexandra, Morgan, Angharad R., Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K., Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle S., Passmore, Peter A., Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A. David, Love, Seth, Kehoe, Patrick G., Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Schürmann, Britta, van den Bussche, Hendrik, Heuser, Isabella, Peters, Oliver, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Rujescu, Dan, Goate, Alison M., Kauwe, John S. K., Cruchaga, Carlos, Nowotny, Petra, Morris, John C., Mayo, Kevin, Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panos, Al-Chalabi, Ammar, Shaw, Christopher E., Singleton, Andrew B., Guerreiro, Rita, Mühleisen, Thomas W., Nöthen, Markus M., Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H.-Erich, Rüther, Eckhard, Carrasquillo, Minerva M., Pankratz, V. Shane, Younkin, Steven G., Hardy, John, O'Donovan, Michael C., Owen, Michael J., Williams, Julie
Publicado 2010