Integrin αvβ6 as a Target for Tumor-Specific Imaging of Vulvar Squamous Cell Carcinoma and Adjacent Premalignant Lesions

por Huisman, Bertine W., Cankat, Merve, Bosse, Tjalling, Vahrmeijer, Alexander L., Rissmann, Robert, Burggraaf, Jacobus, Sier, Cornelis F. M., van Poelgeest, Mariette I. E.
Publicado 2021

Performance of the pattern‐based interpretation of p53 immunohistochemistry as a surrogate for TP53 mutations in vulvar squamous cell carcinoma

por Kortekaas, Kim E, Solleveld‐Westerink, Nienke, Tessier‐Cloutier, Basile, Rutten, Tessa A, Poelgeest, Mariëtte I E, Gilks, C Blake, Hoang, Lien N, Bosse, Tjalling
Publicado 2020

Trends in Incidence and Survival of 1496 Patients with Mucosal Melanoma in The Netherlands (1990–2019)

por Boer, Florine L., Ho, Vincent K. Y., Louwman, Marieke W. J., Schrader, Anne M. R., Zuur, Charlotte L., Blank, Christian U., van Poelgeest, Mariette I. E., Kapiteijn, Ellen H. W.
Publicado 2023

Primary vulvar squamous cell carcinomas with high T cell infiltration and active immune signaling are potential candidates for neoadjuvant PD-1/PD-L1 immunotherapy

por Kortekaas, Kim E, Santegoets, Saskia J, Tas, Liselotte, Ehsan, Ilina, Charoentong, Pornpimol, van Doorn, Helena C, van Poelgeest, Mariette I E, Mustafa, Dana A M, van der Burg, Sjoerd H
Publicado 2021

The Human Vulvar Microbiome: A Systematic Review

por Pagan, Lisa, Ederveen, Roos A. M., Huisman, Bertine W., Schoones, Jan W., Zwittink, Romy D., Schuren, Frank H. J., Rissmann, Robert, Piek, Jurgen M. J., van Poelgeest, Mariëtte I. E.
Publicado 2021

Monitoring of Ex Vivo Cyclosporin a Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics

por in ’t Veld, Aliede E., Jansen, Manon A. A., Huisman, Bertine W., Schoonakker, Mascha, de Kam, Marieke L., Moes, Dirk Jan A. R., van Poelgeest, Mariëtte I. E., Burggraaf, Jacobus, Moerland, Matthijs
Publicado 2022

Immune Monitoring of Mycophenolate Mofetil Activity in Healthy Volunteers Using Ex Vivo T Cell Function Assays

por in ’t Veld, Aliede E., Jansen, Manon A. A., de Kam, Marieke L., Yavuz, Yalҫin, Moes, Dirk Jan A. R., Oudhoff, Kathalijne A., van Poelgeest, Mariette I. E., Burggraaf, Jacobus, Moerland, Matthijs
Publicado 2023

Pre-existing inflammatory immune microenvironment predicts the clinical response of vulvar high-grade squamous intraepithelial lesions to therapeutic HPV16 vaccination

por Abdulrahman, Ziena, de Miranda, Noel, van Esch, Edith M G, de Vos van Steenwijk, Peggy J, Nijman, Hans W, J. P. Welters, Marij, van Poelgeest, Mariette I E, van der Burg, Sjoerd H
Publicado 2020

A pre‐existing coordinated inflammatory microenvironment is associated with complete response of vulvar high‐grade squamous intraepithelial lesions to different forms of immunother...

por Abdulrahman, Ziena, de Miranda, Noel F. C. C., Hellebrekers, Bart W. J., de Vos van Steenwijk, Peggy J., van Esch, Edith M. G., van der Burg, Sjoerd H., van Poelgeest, Mariette I. E.
Publicado 2020

High numbers of activated helper T cells are associated with better clinical outcome in early stage vulvar cancer, irrespective of HPV or p53 status

por Kortekaas, Kim E., Santegoets, Saskia J., Abdulrahman, Ziena, van Ham, Vanessa J., van der Tol, Marij, Ehsan, Ilina, van Doorn, Helena C., Bosse, Tjalling, van Poelgeest, Mariëtte I. E., van der Burg, Sjoerd H.
Publicado 2019

Dermatoscopy and Optical Coherence Tomography in Vulvar High-Grade Squamous Intraepithelial Lesions and Lichen Sclerosus: A Prospective Observational Trial

por Huisman, Bertine W., Pagan, Lisa, Naafs, Rosanne G.C., ten Voorde, Wouter, Rissmann, Robert, Piek, Jurgen M.J., Damman, Jeffrey, Juachon, Maria J., Osse, Michelle, Niemeyer-van der Kolk, Tessa, van Hees, Colette L.M., van Poelgeest, Mariette I.E.
Publicado 2023

Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17

por Tummers, Quirijn R.J.G., Hoogstins, Charlotte E.S., Gaarenstroom, Katja N., de Kroon, Cor D., van Poelgeest, Mariette I.E., Vuyk, Jaap, Bosse, Tjalling, Smit, Vincent T.H.B.M, van de Velde, Cornelis J.H., Cohen, Adam F., Low, Philip S., Burggraaf, Jacobus, Vahrmeijer, Alexander L.
Publicado 2016

Potential use of lymph node-derived HPV-specific T cells for adoptive cell therapy of cervical cancer

por van Poelgeest, Mariëtte I. E., Visconti, Valeria V., Aghai, Zohara, van Ham, Vanessa J., Heusinkveld, Moniek, Zandvliet, Maarten L., Valentijn, A. Rob P. M., Goedemans, Renske, van der Minne, Caroline E., Verdegaal, Els M. E., Trimbos, J. Baptist M. Z., van der Burg, Sjoerd H., Welters, Marij J. P.
Publicado 2016

CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors

por Duurland, Chantal L, Santegoets, Saskia J, Abdulrahman, Ziena, Loof, Nikki M, Sturm, Gregor, Wesselink, Tom H, Arens, Ramon, Boekestijn, Sanne, Ehsan, Ilina, van Poelgeest, Mariette I E, Finotello, Francesca, Hackl, Hubert, Trajanoski, Zlatko, ten Dijke, Peter, Braud, Veronique M, Welters, Marij J P, van der Burg, Sjoerd H
Publicado 2022

A phase 1/2 study combining gemcitabine, Pegintron and p53 SLP vaccine in patients with platinum-resistant ovarian cancer

por Dijkgraaf, Eveline M., Santegoets, Saskia J.A.M., Reyners, An K.L., Goedemans, Renske, Nijman, Hans W., van Poelgeest, Mariëtte I.E., van Erkel, Arien R., Smit, Vincent T.H.B.M., Daemen, Toos A.H.H., van der Hoeven, Jacobus J.M., Melief, Cornelis J.M., Welters, Marij J.P., Kroep, Judith R., van der Burg, Sjoerd H.
Publicado 2015

PROTECT: Prospective Phase-II-Trial Evaluating Adaptive Proton Therapy for Cervical Cancer to Reduce the Impact on Morbidity and the Immune System

por Corbeau, Anouk, Nout, Remi A., Mens, Jan Willem M., Horeweg, Nanda, Godart, Jérémy, Kerkhof, Ellen M., Kuipers, Sander C., van Poelgeest, Mariette I. E., Kroep, Judith R., Boere, Ingrid A., van Doorn, Helena C., Hoogeman, Mischa S., van der Heide, Uulke A., Putter, Hein, Welters, Marij J. P., van der Burg, Sjoerd H., Creutzberg, Carien L., de Boer, Stephanie M.
Publicado 2021

HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial

por van Poelgeest, Mariette I E, Welters, Marij J P, van Esch, Edith M G, Stynenbosch, Linda F M, Kerpershoek, Gijs, van Persijn van Meerten, Els L, van den Hende, Muriel, Löwik, Margriet J G, Berends-van der Meer, Dorien M A, Fathers, Lorraine M, Valentijn, A Rob P M, Oostendorp, Jaap, Fleuren, Gert Jan, Melief, Cornelis J M, Kenter, Gemma G, van der Burg, Sjoerd H
Publicado 2013

Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16...

por Speetjens, Frank M, Welters, Marij J P, Slingerland, Marije, van Poelgeest, Mariette I E, de Vos van Steenwijk, Peggy J, Roozen, Inge, Boekestijn, Sanne, Loof, Nikki M, Zom, Gijs G, Valentijn, A Rob P M, Krebber, Willem-Jan, Meeuwenoord, Nico J, Janssen, Catharina A H, Melief, Cornelis J M, van der Marel, Gijs A, Filippov, Dmitri V, van der Burg, Sjoerd H, Gelderblom, Hans, Ossendorp, Ferry
Publicado 2022

Practical Guidance for Measuring and Reporting Surgical Margins in Vulvar Cancer

por Kortekaas, Kim E., Van de Vijver, Koen K., van Poelgeest, Mariëtte I.E., Gilks, C. Blake, Smit, Vincent T.H.B.M., Arif, Saimah, Arora, Deep, Faruqi, Asma, Ganesan, Raji, Griffin, Nicholas R., Hale, Richard, Hock, Yelin E., Horn, Lars-Christian, McCluggage, W. Glenn, Mukonoweshuro, Pinias, Park, Kay J., Rous, Brian, Tanchel, Bruce, Van Rompuy, Anne-Sophie, van Schalkwyk, Gerry, Vella, Jo, Vergine, Marco, Singh, Naveena, Bosse, Tjalling
Publicado 2020