OntoBrowser: a collaborative tool for curation of ontologies by subject matter experts

por Ravagli, Carlo, Pognan, Francois, Marc, Philippe
Publicado 2017

Liver enzyme delayed clearance in rat treated by CSF1 receptor specific antagonist Sotuletinib

por Pognan, François, Buono, Chiara, Couttet, Philippe, Galarneau, Jean-René, Timsit, Yoav, Wolf, Armin
Publicado 2022

The eTOX Data-Sharing Project to Advance in Silico Drug-Induced Toxicity Prediction

por Cases, Montserrat, Briggs, Katharine, Steger-Hartmann, Thomas, Pognan, François, Marc, Philippe, Kleinöder, Thomas, Schwab, Christof H., Pastor, Manuel, Wichard, Jörg, Sanz, Ferran
Publicado 2014

Inroads to Predict in Vivo Toxicology—An Introduction to the eTOX Project

por Briggs, Katharine, Cases, Montserrat, Heard, David J., Pastor, Manuel, Pognan, François, Sanz, Ferran, Schwab, Christof H., Steger-Hartmann, Thomas, Sutter, Andreas, Watson, David K., Wichard, Jörg D.
Publicado 2012

Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

por Atienzar, Franck A., Blomme, Eric A., Chen, Minjun, Hewitt, Philip, Kenna, J. Gerry, Labbe, Gilles, Moulin, Frederic, Pognan, Francois, Roth, Adrian B., Suter-Dick, Laura, Ukairo, Okechukwu, Weaver, Richard J., Will, Yvonne, Dambach, Donna M.
Publicado 2016

Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina

por Dorgau, Birthe, Georgiou, Maria, Chaudhary, Alexander, Moya-Molina, Marina, Collin, Joseph, Queen, Rachel, Hilgen, Gerrit, Davey, Tracey, Hewitt, Philip, Schmitt, Michael, Kustermann, Stefan, Pognan, Francois, Steel, David H, Sernagor, Evelyne, Armstrong, Lyle, Lako, Majlinda
Publicado 2022

The evolving role of investigative toxicology in the pharmaceutical industry

por Pognan, Francois, Beilmann, Mario, Boonen, Harrie C. M., Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Oinonen, Teija, Roth, Adrian, Steger-Hartmann, Thomas, Valentin, Jean-Pierre, Van Goethem, Freddy, Weaver, Richard J., Newham, Peter
Publicado 2023

Perturbation of microRNAs in Rat Heart during Chronic Doxorubicin Treatment

por Vacchi-Suzzi, Caterina, Bauer, Yasmina, Berridge, Brian R., Bongiovanni, Sandrine, Gerrish, Kevin, Hamadeh, Hisham K., Letzkus, Martin, Lyon, Jonathan, Moggs, Jonathan, Paules, Richard S., Pognan, François, Staedtler, Frank, Vidgeon-Hart, Martin P., Grenet, Olivier, Couttet, Philippe
Publicado 2012

Incorporating microglia‐like cells in human induced pluripotent stem cell‐derived retinal organoids

por Chichagova, Valeria, Georgiou, Maria, Carter, Madeleine, Dorgau, Birthe, Hilgen, Gerrit, Collin, Joseph, Queen, Rachel, Chung, Git, Ajeian, Jila, Moya‐Molina, Marina, Kustermann, Stefan, Pognan, Francois, Hewitt, Philip, Schmitt, Michael, Sernagor, Evelyne, Armstrong, Lyle, Lako, Majlinda
Publicado 2023

Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human

por Pognan, Francois, Mahl, J. Andreas, Papoutsi, Maria, Ledieu, David, Raccuglia, Marc, Theil, Diethilde, Voytek, Sarah B., Devine, Patrick J., Kubek-Luck, Katie, Claudio, Natalie, Cordier, Andre, Heier, Annabelle, Kolly, Carine, Hartmann, Andreas, Chibout, Salah-Dine, Bouchard, Page, Trendelenburg, Christian
Publicado 2018

Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

por Tummino, Tia A., Rezelj, Veronica V., Fischer, Benoit, Fischer, Audrey, O’Meara, Matthew J., Monel, Blandine, Vallet, Thomas, Zhang, Ziyang, Alon, Assaf, O’Donnell, Henry R., Lyu, Jiankun, Schadt, Heiko, White, Kris M, Krogan, Nevan J., Urban, Laszlo, Shokat, Kevan M., Kruse, Andrew C., García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K.
Publicado 2021

The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives

por Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Blomberg, Niklas, Bringezu, Frank, Briggs, Katharine, Callegaro, Giulia, Capella-Gutierrez, Salvador, Centeno, Emilio, Corvi, Javier, Drew, Philip, Drewe, William C., Fernández, José M., Furlong, Laura I., Guney, Emre, Kors, Jan A., Mayer, Miguel Angel, Pastor, Manuel, Piñero, Janet, Ramírez-Anguita, Juan Manuel, Ronzano, Francesco, Rowell, Philip, Saüch-Pitarch, Josep, Valencia, Alfonso, van de Water, Bob, van der Lei, Johan, van Mulligen, Erik, Sanz, Ferran
Publicado 2021

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2

por Tummino, Tia A., Rezelj, Veronica V., Fischer, Benoit, Fischer, Audrey, O’Meara, Matthew J., Monel, Blandine, Vallet, Thomas, White, Kris M., Zhang, Ziyang, Alon, Assaf, Schadt, Heiko, O’Donnell, Henry R., Lyu, Jiankun, Rosales, Romel, McGovern, Briana L., Rathnasinghe, Raveen, Jangra, Sonia, Schotsaert, Michael, Galarneau, Jean-René, Krogan, Nevan J., Urban, Laszlo, Shokat, Kevan M., Kruse, Andrew C., García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K.
Publicado 2021