Functional roles of SRC signaling in pancreatic cancer: Recent insights provide novel therapeutic opportunities

por Poh, Ashleigh R., Ernst, Matthias
Publicado 2023

Targeting Macrophages in Cancer: From Bench to Bedside

por Poh, Ashleigh R., Ernst, Matthias
Publicado 2018

Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma: Therapeutic Opportunities and Clinical Challenges

por Poh, Ashleigh R., Ernst, Matthias
Publicado 2021

Multicellular Effects of STAT3 in Non-small Cell Lung Cancer: Mechanistic Insights and Therapeutic Opportunities

por Parakh, Sagun, Ernst, Matthias, Poh, Ashleigh R.
Publicado 2021

An intrasplenic injection model of pancreatic cancer metastasis to the liver in mice

por O’Brien, Megan, Ernst, Matthias, Poh, Ashleigh R.
Publicado 2023

Longitudinal quantification of mouse gastric tumor organoid viability and growth using luminescence and microscopy

por Morrow, Riley J., Ernst, Matthias, Poh, Ashleigh R.
Publicado 2023

Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells

por Poh, Ashleigh R., O'Donoghue, Robert J.J., Ernst, Matthias
Publicado 2015

Targeting H(i)ck education for cancer therapy?

por Ernst, Matthias, O'Donoghue, Robert J.J., Poh, Ashleigh R.
Publicado 2017

Editorial: Overcoming drug relapse and therapy resistance in NSCLC

por Parakh, Sagun, Leong, Tracy L., Best, Sarah A., Poh, Ashleigh R.
Publicado 2023

Mouse models for gastric cancer: Matching models to biological questions

por Poh, Ashleigh R, O'Donoghue, Robert J J, Ernst, Matthias, Putoczki, Tracy L
Publicado 2016

Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages

por Morrow, Riley J., Allam, Amr H., Konecnik, Josh, Baloyan, David, Dijkstra, Christine, Eissmann, Moritz F., Jacob, Saumya P., O’Brien, Megan, Poh, Ashleigh R., Ernst, Matthias
Publicado 2022

A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development

por O’Keefe, Ryan N., Carli, Annalisa L. E., Baloyan, David, Chisanga, David, Shi, Wei, Afshar-Sterle, Shoukat, Eissmann, Moritz F., Poh, Ashleigh R., Pal, Bhupinder, Seillet, Cyril, Locksley, Richard M., Ernst, Matthias, Buchert, Michael
Publicado 2023

A novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma

por Arulananda, Surein, O’Brien, Megan, Evangelista, Marco, Jenkins, Laura J., Poh, Ashleigh R., Walkiewicz, Marzena, Leong, Trishe, Mariadason, John M., Cebon, Jonathan, Balachander, Srividya B., Cidado, Justin R., Lee, Erinna F., John, Thomas, Fairlie, Walter D.
Publicado 2021

IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization

por Eissmann, Moritz F., Dijkstra, Christine, Jarnicki, Andrew, Phesse, Toby, Brunnberg, Jamina, Poh, Ashleigh R., Etemadi, Nima, Tsantikos, Evelyn, Thiem, Stefan, Huntington, Nicholas D., Hibbs, Margaret L., Boussioutas, Alex, Grimbaldeston, Michele A., Buchert, Michael, O’Donoghue, Robert J. J., Masson, Frederick, Ernst, Matthias
Publicado 2019

Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth

por Thilakasiri, Pathum, Huynh, Jennifer, Poh, Ashleigh R, Tan, Chin Wee, Nero, Tracy L, Tran, Kelly, Parslow, Adam C, Afshar‐Sterle, Shoukat, Baloyan, David, Hannan, Natalie J, Buchert, Michael, Scott, Andrew Mark, Griffin, Michael DW, Hollande, Frederic, Parker, Michael W, Putoczki, Tracy L, Ernst, Matthias, Chand, Ashwini L
Publicado 2019

BCL-XL is an actionable target for treatment of malignant pleural mesothelioma

por Arulananda, Surein, O’Brien, Megan, Evangelista, Marco, Harris, Tiffany J., Steinohrt, Nikita S., Jenkins, Laura J., Walkiewicz, Marzena, O’Donoghue, Robert J. J., Poh, Ashleigh R., Thapa, Bibhusal, Williams, David S., Leong, Trishe, Mariadason, John M., Li, Xia, Cebon, Jonathan, Lee, Erinna F., John, Thomas, Fairlie, W. D.
Publicado 2020

Correction: BCL-XL is an actionable target for treatment of malignant pleural mesothelioma

por Arulananda, Surein, O’Brien, Megan, Evangelista, Marco, Harris, Tiffany J., Steinohrt, Nikita S., Jenkins, Laura J., Walkiewicz, Marzena, O’Donoghue, Robert J. J., Poh, Ashleigh R., Thapa, Bibhusal, Williams, David S., Leong, Trishe, Mariadason, John M., Li, Xia, Cebon, Jonathan, Lee, Erinna F., John, Thomas, Fairlie, W. Douglas
Publicado 2021

Mechanisms of cellular crosstalk in the gastric tumor microenvironment are mediated by YAP1 and STAT3

por Thilakasiri, Pathum, O’Keefe, Ryan N, To, Sarah Q, Chisanga, David, Eissmann, Moritz F, Carli, Annalisa LE, Duscio, Belinda, Baloyan, David, Dmello, Rhynelle S, Williams, David, Mariadason, John, Poh, Ashleigh R, Pal, Bhupinder, Kile, Benjamin T, Vissers, Joseph HA, Harvey, Kieran F, Buchert, Michael, Shi, Wei, Ernst, Matthias, Chand, Ashwini L
Publicado 2023

Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy

por Poh, Ashleigh R., Love, Christopher G., Chisanga, David, Steer, James H., Baloyan, David, Chopin, Michaël, Nutt, Stephen, Rautela, Jai, Huntington, Nicholas D., Etemadi, Nima, O’Brien, Megan, O’Keefe, Ryan, Ellies, Lesley G., Macri, Christophe, Mintern, Justine D., Whitehead, Lachlan, Gangadhara, Gangadhara, Boon, Louis, Chand, Ashwini L., Lowell, Clifford A., Shi, Wei, Pixley, Fiona J., Ernst, Matthias
Publicado 2022

Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer

por Nguyen, Paul M., Dagley, Laura F., Preaudet, Adele, Lam, Nga, Giam, Maybelline, Fung, Ka Yee, Aizel, Kaheina, van Duijneveldt, Gemma, Tan, Chin Wee, Hirokawa, Yumiko, Yip, Hon Yan K., Love, Christopher G., Poh, Ashleigh R., Cruz, Akshay D’, Burstroem, Charlotte, Feltham, Rebecca, Abdirahman, Suad M., Meiselbach, Kristy, Low, Ronnie Ren Jie, Palmieri, Michelle, Ernst, Matthias, Webb, Andrew I., Burgess, Tony, Sieber, Oliver M., Bouillet, Philippe, Putoczki, Tracy L.
Publicado 2019