Description of Chemical Synthesis, Nuclear Magnetic Resonance Characterization and Biological Activity of Estrane-Based Inhibitors/Activators of Steroidogenesis

por Poirier, Donald
Publicado 2023

Crucial Role of 3-Bromoethyl in Removing the Estrogenic Activity of 17β-HSD1 Inhibitor 16β-(m-Carbamoylbenzyl)estradiol

por Maltais, René, Ayan, Diana, Poirier, Donald
Publicado 2011

Preparation of 16β-Estradiol Derivative Libraries as Bisubstrate Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 Using the Multidetachable Sulfamate Linker

por Bérubé, Marie, Delagoutte, Florian, Poirier, Donald
Publicado 2010

A Targeted-Covalent Inhibitor of 17β-HSD1 Blocks Two Estrogen-Biosynthesis Pathways: In Vitro (Metabolism) and In Vivo (Xenograft) Studies in T-47D Breast Cancer Models

por Poirier, Donald, Roy, Jenny, Maltais, René
Publicado 2021

Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation o...

por Ngueta, Adrien Djiemeny, Roy, Jenny, Maltais, René, Poirier, Donald
Publicado 2023

Synthesis of 5α-Androstane-17-spiro-δ-lactones with a 3-Keto, 3-Hydroxy, 3-Spirocarbamate or 3-Spiromorpholinone as Inhibitors of 17β-Hydroxysteroid Dehydrogenases

por Djigoué, Guy Bertrand, Ngatcha, Béatrice Tchédam, Roy, Jenny, Poirier, Donald
Publicado 2013

An Aminosteroid Derivative Shows Higher In Vitro and In Vivo Potencies than Gold Standard Drugs in Androgen-Dependent Prostate Cancer Models

por Poirier, Donald, Roy, Jenny, Maltais, René, Weidmann, Cindy, Audet-Walsh, Étienne
Publicado 2023

The Aminosteroid Derivative RM-133 Shows In Vitro and In Vivo Antitumor Activity in Human Ovarian and Pancreatic Cancers

por Kenmogne, Lucie Carolle, Ayan, Diana, Roy, Jenny, Maltais, René, Poirier, Donald
Publicado 2015

Synthesis and Characterization of Some New Cu(II), Ni(II) and Zn(II) Complexes with Salicylidene Thiosemicarbazones: Antibacterial, Antifungal and in Vitro Antileukemia Activity

por Pahontu, Elena, Fala, Valeriu, Gulea, Aurelian, Poirier, Donald, Tapcov, Victor, Rosu, Tudor
Publicado 2013

Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel

por Maltais, René, Roy, Jenny, Perreault, Martin, Sato, Sachiko, Lévesque, Julie-Christine, Poirier, Donald
Publicado 2021

Investigation of the In Vitro and In Vivo efficiency of RM-532-105, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, in LAPC-4 prostate cancer cell and tumor models

por Kenmogne, Lucie Carolle, Roy, Jenny, Maltais, René, Rouleau, Mélanie, Neveu, Bertrand, Pouliot, Frédéric, Poirier, Donald
Publicado 2017

Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments

por Burguin, Anna, Roy, Jenny, Ouellette, Geneviève, Maltais, René, Bherer, Juliette, Diorio, Caroline, Poirier, Donald, Durocher, Francine
Publicado 2023

Very-long-chain fatty acid metabolic capacity of 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) promotes replication of hepatitis C virus and related flaviviruses

por Mohamed, Bassim, Mazeaud, Clément, Baril, Martin, Poirier, Donald, Sow, Aïssatou Aïcha, Chatel-Chaix, Laurent, Titorenko, Vladimir, Lamarre, Daniel
Publicado 2020

Synthesis and Characterization of Novel Cu(II), Pd(II) and Pt(II) Complexes with 8-Ethyl-2-hydroxytricyclo(7.3.1.0(2,7))tridecan-13-one-thiosemicarbazone: Antimicrobial and in Vitr...

por Pahonțu, Elena, Paraschivescu, Codruța, Ilieș, Diana-Carolina, Poirier, Donald, Oprean, Camelia, Păunescu, Virgil, Gulea, Aurelian, Roșu, Tudor, Bratu, Ovidiu
Publicado 2016