Carcinoma-Associated Fibroblasts Are a Promising Therapeutic Target

por Togo, Shinsaku, Polanska, Urszula M., Horimoto, Yoshiya, Orimo, Akira
Publicado 2013

The use of (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor

por Maynard, Juliana, Emmas, Sally-Ann, Blé, Francois-Xavier, Barjat, Hervé, Lawrie, Emily, Hancox, Urs, Oakes, Deborah, Polanska, Urszula M., Barry, Simon T.
Publicado 2016

The use of (18)F-Fluoro-deoxy-glucose positron emission tomography ((18)F-FDG PET) as a non-invasive pharmacodynamic biomarker to determine the minimally pharmacologically active d...

por Maynard, Juliana, Emmas, Sally-Ann, Ble, Francois-Xavier, Barjat, Herve, Lawrie, Emily, Hancox, Urs, Polanska, Urszula M., Pritchard, Alison, Hudson, Kevin
Publicado 2017

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours

por Ordonez, Liliana D., Hay, Trevor, McEwen, Robert, Polanska, Urszula M., Hughes, Adina, Delpuech, Oona, Cadogan, Elaine, Powell, Steve, Dry, Jonathan, Tornillo, Giusy, Silcock, Lucy, Leo, Elisabetta, O’Connor, Mark J., Clarke, Alan R., Smalley, Matthew J.
Publicado 2019

Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors

por Chou, David B., Furlong, Brooke A., Posey, Ryan R., Kyprianou, Christos, O’Sullivan, Lucy R., David, Rhiannon, Randle, Suzanne J., Polanska, Urszula M., Travers, Jon, Urosevic, Jelena, Hutchinson, John N., Che, Jianwei, Howley, Anna M., Hasserjian, Robert P., Prantil-Baun, Rachelle, Ingber, Donald E.
Publicado 2022

BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors

por Bertran-Alamillo, Jordi, Giménez-Capitán, Ana, Román, Ruth, Talbot, Sara, Whiteley, Rebecca, Floc’h, Nicolas, Martínez-Pérez, Elizabeth, Martin, Matthew J., Smith, Paul D., Sullivan, Ivana, Terp, Mikkel G., Saeh, Jamal, Marino-Buslje, Cristina, Fabbri, Giulia, Guo, Grace, Xu, Man, Tornador, Cristian, Aguilar-Hernández, Andrés, Reguart, Noemí, Ditzel, Henrik J., Martínez-Bueno, Alejandro, Nabau-Moretó, Núria, Gascó, Amaya, Rosell, Rafael, Pease, J. Elizabeth, Polanska, Urszula M., Travers, Jon, Urosevic, Jelena, Molina-Vila, Miguel A.
Publicado 2023

Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance

por Serra, Violeta, Wang, Anderson T., Castroviejo-Bermejo, Marta, Polanska, Urszula M., Palafox, Marta, Herencia-Ropero, Andrea, Jones, Gemma N., Lai, Zhongwu, Armenia, Joshua, Michopoulos, Filippos, Llop-Guevara, Alba, Brough, Rachel, Gulati, Aditi, Pettitt, Stephen J., Bulusu, Krishna C., Nikkilä, Jenni, Wilson, Zena, Hughes, Adina, Wijnhoven, Paul W.G., Ahmed, Ambar, Bruna, Alejandra, Gris-Oliver, Albert, Guzman, Marta, Rodríguez, Olga, Grueso, Judit, Arribas, Joaquin, Cortés, Javier, Saura, Cristina, Lau, Alan, Critchlow, Susan, Dougherty, Brian, Caldas, Carlos, Mills, Gordon B., Barrett, J. Carl, Forment, Josep V., Cadogan, Elaine, Lord, Christopher J., Cruz, Cristina, Balmaña, Judith, O'Connor, Mark J.
Publicado 2022