B(12) cofactors directly stabilize an mRNA regulatory switch

por Johnson, James E., Reyes, Francis E., Polaski, Jacob T., Batey, Robert T.
Publicado 2012

Single-Molecule Conformational Dynamics of a Biologically Functional Hydroxocobalamin Riboswitch

por Holmstrom, Erik D., Polaski, Jacob T., Batey, Robert T., Nesbitt, David J.
Publicado 2014

Mechanistic Insights into Cofactor-Dependent Coupling of RNA Folding and mRNA Transcription/Translation by a Cobalamin Riboswitch

por Polaski, Jacob T., Holmstrom, Erik D., Nesbitt, David J., Batey, Robert T.
Publicado 2016

Recurrent RNA motifs as scaffolds for genetically encodable small molecule biosensors

por Porter, Ely B., Polaski, Jacob T., Morck, Makenna M., Batey, Robert T.
Publicado 2017

A functional genetic screen reveals sequence preferences within a key tertiary interaction in cobalamin riboswitches required for ligand selectivity

por Polaski, Jacob T, Kletzien, Otto A, Drogalis, Lea K, Batey, Robert T
Publicado 2018

Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs

por Arnesen, Spencer, Polaski, Jacob T, Blanchard, Zannel, Osborne, Kyle S, Welm, Alana L, O’Connell, Ryan M, Gertz, Jason
Publicado 2023

The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma

por Polaski, Jacob T, Udy, Dylan B, Escobar-Hoyos, Luisa F, Askan, Gokce, Leach, Steven D, Ventura, Andrea, Kannan, Ram, Bradley, Robert K
Publicado 2021

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

por Braselmann, Esther, Wierzba, Aleksandra J., Polaski, Jacob T., Chromiński, Mikołaj, Holmes, Zachariah E., Hung, Sheng-Ting, Batan, Dilara, Wheeler, Joshua R., Parker, Roy, Jimenez, Ralph, Gryko, Dorota, Batey, Robert T., Palmer, Amy E.
Publicado 2018

Characterization of HCI-EC-23 a novel estrogen- and progesterone-responsive endometrial cancer cell line

por Rush, Craig M., Blanchard, Zannel, Polaski, Jacob T., Osborne, Kyle S., Osby, Krystle, Vahrenkamp, Jeffery M., Yang, Chieh-Hsiang, Lum, David H., Hagan, Christy R., Leslie, Kimberly K., Pufall, Miles A., Thiel, Kristina W., Gertz, Jason
Publicado 2022

RNA isoform screens uncover the essentiality and tumor suppressor activity of ultraconserved poison exons

por Thomas, James D., Polaski, Jacob T., Feng, Qing, De Neef, Emma J., Hoppe, Emma R., McSharry, Maria V., Pangallo, Joseph, Gabel, Austin M., Belleville, Andrea E., Watson, Jacqueline, Nkinsi, Naomi T., Berger, Alice H., Bradley, Robert K.
Publicado 2020

Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells

por North, Khrystyna, Benbarche, Salima, Liu, Bo, Pangallo, Joseph, Chen, Sisi, Stahl, Maximilian, Bewersdorf, Jan Philipp, Stanley, Robert F., Erickson, Caroline, Cho, Hana, Pineda, Jose Mario Bello, Thomas, James D., Polaski, Jacob T., Belleville, Andrea E., Gabel, Austin M., Udy, Dylan B., Humbert, Olivier, Kiem, Hans-Peter, Abdel-Wahab, Omar, Bradley, Robert K.
Publicado 2022

Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition

por Inoue, Daichi, Polaski, Jacob T., Taylor, Justin, Castel, Pau, Chen, Sisi, Kobayashi, Susumu, Hogg, Simon J., Hayashi, Yasutaka, Pineda, Jose Mario Bello, El Marabti, Ettaib, Erickson, Caroline, Knorr, Katherine, Fukumoto, Miki, Yamazaki, Hiromi, Tanaka, Atsushi, Fukui, Chie, Lu, Sydney X., Durham, Benjamin H., Liu, Bo, Wang, Eric, Mehta, Sanjoy, Zakheim, Daniel, Garippa, Ralph, Penson, Alex, Chew, Guo-Liang, McCormick, Frank, Bradley, Robert K., Abdel-Wahab, Omar
Publicado 2021