The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure

por Polhemus, David J., Calvert, John W., Butler, Javed, Lefer, David J.
Publicado 2014

Hydrogen Sulfide Levels and Nuclear Factor-Erythroid 2-Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)

por Islam, Kazi N, Polhemus, David J, Donnarumma, Erminia, Brewster, Luke P, Lefer, David J
Publicado 2015

A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

por Polhemus, David J., Li, Zhen, Pattillo, Christopher B., Gojon, Gabriel, Gojon, Gabriel, Giordano, Tony, Krum, Henry
Publicado 2015

Hydrogen Sulfide as a Potential Therapy for Heart Failure—Past, Present, and Future

por LaPenna, Kyle B., Polhemus, David J., Doiron, Jake E., Hidalgo, Hunter A., Li, Zhen, Lefer, David J.
Publicado 2021

Combined Angiotensin Receptor–Neprilysin Inhibitors Improve Cardiac and Vascular Function Via Increased NO Bioavailability in Heart Failure

por Trivedi, Rishi K., Polhemus, David J., Li, Zhen, Yoo, Daniel, Koiwaya, Hiroshi, Scarborough, Amy, Goodchild, Traci T., Lefer, David J.
Publicado 2018

Radiofrequency Renal Denervation Protects the Ischemic Heart via Inhibition of GRK2 and Increased Nitric Oxide Signaling

por Polhemus, David J., Gao, Juan, Scarborough, Amy L., Trivedi, Rishi, McDonough, Kathleen H., Goodchild, Traci T., Smart, Frank, Kapusta, Daniel R., Lefer, David J.
Publicado 2016

Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure

por Organ, Chelsea L., Li, Zhen, Sharp, Thomas E., Polhemus, David J., Gupta, Nilaksh, Goodchild, Traci T., Tang, W. H. Wilson, Hazen, Stanley L., Lefer, David J.
Publicado 2020

Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure

por Li, Zhen, Organ, Chelsea L., Kang, Jianming, Polhemus, David J., Trivedi, Rishi K., Sharp, Thomas E., Jenkins, Jack S., Tao, Ya-xiong, Xian, Ming, Lefer, David J.
Publicado 2018

Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury

por Xia, Huijing, Li, Zhen, Sharp, Thomas E., Polhemus, David J., Carnal, Jean, Moles, Karl H., Tao, Ya‐Xiong, Elrod, John, Pfeilschifter, Josef, Beck, Karl‐Friedrich, Lefer, David J.
Publicado 2020

Novel Göttingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities

por Sharp, Thomas E., Scarborough, Amy L., Li, Zhen, Polhemus, David J., Hidalgo, Hunter A., Schumacher, Jeffery D., Matsuura, Timothy R., Jenkins, J. Stephen, Kelly, Daniel P., Goodchild, Traci T., Lefer, David J.
Publicado 2021

Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a “2‐Hit” Murine Model

por LaPenna, Kyle B., Li, Zhen, Doiron, Jake E., Sharp, Thomas E., Xia, Huijing, Moles, Karl, Koul, Kashyap, Wang, John S., Polhemus, David J., Goodchild, Traci T., Patel, Ravi B., Shah, Sanjiv J., Lefer, David J.
Publicado 2023

Zofenopril Protects Against Myocardial Ischemia–Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability

por Donnarumma, Erminia, Ali, Murtuza J., Rushing, Amanda M., Scarborough, Amy L., Bradley, Jessica M., Organ, Chelsea L., Islam, Kazi N., Polhemus, David J., Evangelista, Stefano, Cirino, Giuseppe, Jenkins, J. Stephen, Patel, Rajan A. G., Lefer, David J., Goodchild, Traci T.
Publicado 2016