Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein

por Pollitt, Alice Y, Insall, Robert H
Publicado 2009

Platelet Adhesion to Podoplanin Under Flow is Mediated by the Receptor CLEC-2 and Stabilised by Src/Syk-Dependent Platelet Signalling

por Navarro-Núñez, Leyre, Pollitt, Alice Y., Lowe, Kate, Latif, Arusa, Nash, Gerard B., Watson, Steve P.
Publicado 2015

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

por Falet, Hervé, Pollitt, Alice Y., Begonja, Antonija Jurak, Weber, Sarah E., Duerschmied, Daniel, Wagner, Denisa D., Watson, Steve P., Hartwig, John H.
Publicado 2010

Syk-dependent Phosphorylation of CLEC-2: A NOVEL MECHANISM OF HEM-IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIF SIGNALING

por Séverin, Sonia, Pollitt, Alice Y., Navarro-Nuñez, Leyre, Nash, Craig A., Mourão-Sá, Diego, Eble, Johannes A., Senis, Yotis A., Watson, Steve P.
Publicado 2011

Super-Resolution Fluorescence Microscopy Reveals Clustering Behaviour of Chlamydia pneumoniae’s Major Outer Membrane Protein

por Danson, Amy E., McStea, Alex, Wang, Lin, Pollitt, Alice Y., Martin-Fernandez, Marisa L., Moraes, Isabel, Walsh, Martin A., MacIntyre, Sheila, Watson, Kimberly A.
Publicado 2020

Fully automated platelet differential interference contrast image analysis via deep learning

por Kempster, Carly, Butler, George, Kuznecova, Elina, Taylor, Kirk A., Kriek, Neline, Little, Gemma, Sowa, Marcin A., Sage, Tanya, Johnson, Louise J., Gibbins, Jonathan M., Pollitt, Alice Y.
Publicado 2022

Platelet actin nodules are podosome-like structures dependent on Wiskott–Aldrich syndrome protein and ARP2/3 complex

por Poulter, Natalie S., Pollitt, Alice Y., Davies, Amy, Malinova, Dessislava, Nash, Gerard B., Hannon, Mike J., Pikramenou, Zoe, Rappoport, Joshua Z., Hartwig, John H., Owen, Dylan M., Thrasher, Adrian J., Watson, Stephen P., Thomas, Steven G.
Publicado 2015

Syk and Src Family Kinases Regulate C-type Lectin Receptor 2 (CLEC-2)-mediated Clustering of Podoplanin and Platelet Adhesion to Lymphatic Endothelial Cells

por Pollitt, Alice Y., Poulter, Natalie S., Gitz, Eelo, Navarro-Nuñez, Leyre, Wang, Ying-Jie, Hughes, Craig E., Thomas, Steven G., Nieswandt, Bernhard, Douglas, Michael R., Owen, Dylan M., Jackson, David G., Dustin, Michael L., Watson, Steve P.
Publicado 2014

Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation

por Dunster, Joanne L., Unsworth, Amanda J., Bye, Alexander P., Haining, Elizabeth J., Sowa, Marcin A., Di, Ying, Sage, Tanya, Pallini, Chiara, Pike, Jeremy A., Hardy, Alexander T., Nieswandt, Bernhard, García, Ángel, Watson, Steve P., Poulter, Natalie S., Gibbins, Jonathan M., Pollitt, Alice Y.
Publicado 2019

Katacine Is a New Ligand of CLEC-2 that Acts as a Platelet Agonist

por Morán, Luis A., Di, Ying, Sowa, Marcin A., Hermida-Nogueira, Lidia, Barrachina, María N., Martin, Eleyna, Clark, Joanne C., Mize, Todd H., Eble, Johannes A., Moreira, David, Pollitt, Alice Y., Loza, María I., Domínguez, Eduardo, Watson, Steve P., García, Ángel
Publicado 2022

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

por Flierl, Ulrike, Nero, Tracy L., Lim, Bock, Arthur, Jane F., Yao, Yu, Jung, Stephanie M., Gitz, Eelo, Pollitt, Alice Y., Zaldivia, Maria T.K., Jandrot-Perrus, Martine, Schäfer, Andreas, Nieswandt, Bernhard, Andrews, Robert K., Parker, Michael W., Gardiner, Elizabeth E., Peter, Karlheinz
Publicado 2015

Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI

por Nicolson, Phillip L.R., Hughes, Craig E., Watson, Stephanie, Nock, Sophie H., Hardy, Alexander T., Watson, Callum N., Montague, Samantha J., Clifford, Hayley, Huissoon, Aarnoud P., Malcor, Jean-Daniel, Thomas, Mark R., Pollitt, Alice Y., Tomlinson, Michael G., Pratt, Guy, Watson, Steve P.
Publicado 2018

Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists

por Clark, Joanne C., Martin, Eleyna M., Morán, Luis A., Di, Ying, Wang, Xueqing, Zuidscherwoude, Malou, Brown, Helena C., Kavanagh, Deirdre M., Hummert, Johan, Eble, Johannes A., Nieswandt, Bernhard, Stegner, David, Pollitt, Alice Y., Herten, Dirk-Peter, Tomlinson, Michael G., García, Angel, Watson, Steve P.
Publicado 2023

Low-dose Btk inhibitors selectively block platelet activation by CLEC-2

por Nicolson, Phillip L.R., Nock, Sophie H., Hinds, Joshua, Garcia-Quintanilla, Lourdes, Smith, Christopher W., Campos, Joana, Brill, Alexander, Pike, Jeremy A., Khan, Abdullah O., Poulter, Natalie S., Kavanagh, Deidre M., Watson, Stephanie, Watson, Callum N., Clifford, Hayley, Huissoon, Aarnoud P., Pollitt, Alice Y., Eble, Johannes A., Pratt, Guy, Watson, Steve P., Hughes, Craig E.
Publicado 2020