Fibroblast Growth Factor Receptor 2 Isoforms Detected via Novel RNA ISH as Predictive Biomarkers for Progestin Therapy in Atypical Hyperplasia and Low-Grade Endometrial Cancer

por Sengal, Asmerom T., Smith, Deborah, Rogers, Rebecca, Snell, Cameron E., Williams, Elizabeth D., Pollock, Pamela M.
Publicado 2021

Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation

por Karlsson, Thomas, Krakstad, Camilla, Tangen, Ingvild Løberg, Hoivik, Erling A., Pollock, Pamela M., Salvesen, Helga B., Lewis, Aurélia E.
Publicado 2016

Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status

por Byron, Sara A, Loch, David C, Wellens, Candice L, Wortmann, Andreas, Wu, Jiayi, Wang, John, Nomoto, Kenichi, Pollock, Pamela M
Publicado 2012

Spatial expression of the FGFR2b splice isoform and its prognostic significance in endometrioid endometrial carcinoma

por Sengal, Asmerom T, Smith, Deborah, Snell, Cameron E, Leung, Samuel, Talhouk, Aline, Williams, Elizabeth D, McAlpine, Jessica N, Pollock, Pamela M
Publicado 2022

FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features

por Byron, Sara A., Gartside, Michael, Powell, Matthew A., Wellens, Candice L., Gao, Feng, Mutch, David G., Goodfellow, Paul J., Pollock, Pamela M.
Publicado 2012

Correction: FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features

por Byron, Sara A., Gartside, Michael, Powell, Matthew A., Wellens, Candice L., Gao, Feng, Mutch, David G., Goodfellow, Paul J., Pollock, Pamela M.
Publicado 2012

The ‘melanoma-enriched’ microRNA miR-4731-5p acts as a tumour suppressor

por Stark, Mitchell S., Tom, Lisa N., Boyle, Glen M., Bonazzi, Vanessa F., Soyer, H. Peter, Herington, Adrian C., Pollock, Pamela M., Hayward, Nicholas K.
Publicado 2016

Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo

por Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas, McGovern, Jacqui A.
Publicado 2019

Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo

por Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas, McGovern, Jacqui A.
Publicado 2020

Bcl‐2 inhibitors enhance FGFR inhibitor‐induced mitochondrial‐dependent cell death in FGFR2‐mutant endometrial cancer

por Packer, Leisl M., Stehbens, Samantha J., Bonazzi, Vanessa F., Gunter, Jennifer H., Ju, Robert J., Ward, Micheal, Gartside, Michael G., Byron, Sara A., Pollock, Pamela M.
Publicado 2019

Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen

por Bhatia, Sugandha, Blick, Tony, Pinto, Cletus, Waltham, Mark, Monkman, James, Ivanova, Ekaterina, Pollock, Pamela M., Nagaraj, Shivashankar H., Wiegmans, Adrian P., Haviv, Izhak, Simpson, Kaylene J., Thompson, Erik W.
Publicado 2020

miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma

por Stark, Mitchell S., Bonazzi, Vanessa F., Boyle, Glen M., Palmer, Jane M., Symmons, Judith, Lanagan, Catherine M., Schmidt, Christopher W., Herington, Adrian C., Ballotti, Robert, Pollock, Pamela M., Hayward, Nicholas K.
Publicado 2015

Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibitio...

por Eggink, Florine A., Van Gool, Inge C., Leary, Alexandra, Pollock, Pamela M., Crosbie, Emma J., Mileshkin, Linda, Jordanova, Ekaterina S., Adam, Julien, Freeman-Mills, Luke, Church, David N., Creutzberg, Carien L., De Bruyn, Marco, Nijman, Hans W., Bosse, Tjalling
Publicado 2016

The Prognostic and Predictive Value of Melanoma-related MicroRNAs Using Tissue and Serum: A MicroRNA Expression Analysis()

por Stark, Mitchell S., Klein, Kerenaftali, Weide, Benjamin, Haydu, Lauren E., Pflugfelder, Annette, Tang, Yue Hang, Palmer, Jane M., Whiteman, David C., Scolyer, Richard A., Mann, Graham J., Thompson, John F., Long, Georgina V., Barbour, Andrew P., Soyer, H. Peter, Garbe, Claus, Herington, Adrian, Pollock, Pamela M., Hayward, Nicholas K.
Publicado 2015

A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells

por McGovern, Jacqui A., Bock, Nathalie, Shafiee, Abbas, Martine, Laure C., Wagner, Ferdinand, Baldwin, Jeremy G., Landgraf, Marietta, Lahr, Christoph A., Meinert, Christoph, Williams, Elizabeth D., Pollock, Pamela M., Denham, Jim, Russell, Pamela J., Risbridger, Gail P., Clements, Judith A., Loessner, Daniela, Holzapfel, Boris M., Hutmacher, Dietmar W.
Publicado 2021

Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer

por Bonazzi, Vanessa F., Kondrashova, Olga, Smith, Deborah, Nones, Katia, Sengal, Asmerom T., Ju, Robert, Packer, Leisl M., Koufariotis, Lambros T., Kazakoff, Stephen H., Davidson, Aimee L., Ramarao-Milne, Priya, Lakis, Vanessa, Newell, Felicity, Rogers, Rebecca, Davies, Claire, Nicklin, James, Garrett, Andrea, Chetty, Naven, Perrin, Lewis, Pearson, John V., Patch, Ann-Marie, Waddell, Nicola, Pollock, Pamela M.
Publicado 2022

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer

por Harrington, Brittney S., He, Yaowu, Khan, Tashbib, Puttick, Simon, Conroy, Paul J., Kryza, Thomas, Cuda, Tahleesa, Sokolowski, Kamil A, Tse, Brian WC, Robbins, Katherine K., Arachchige, Buddhika J., Stehbens, Samantha J., Pollock, Pamela M., Reed, Sarah, Weroha, S. John, Haluska, Paul, Salomon, Carlos, Lourie, Rohan, Perrin, Lewis C., Law, Ruby H. P., Whisstock, James C., Hooper, John D
Publicado 2020

Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy

por León-Castillo, Alicia, de Boer, Stephanie M., Powell, Melanie E., Mileshkin, Linda R., Mackay, Helen J., Leary, Alexandra, Nijman, Hans W., Singh, Naveena, Pollock, Pamela M., Bessette, Paul, Fyles, Anthony, Haie-Meder, Christine, Smit, Vincent T. H. B. M., Edmondson, Richard J., Putter, Hein, Kitchener, Henry C., Crosbie, Emma J., de Bruyn, Marco, Nout, Remi A., Horeweg, Nanda, Creutzberg, Carien L., Bosse, Tjalling
Publicado 2020