The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology

por Nigam, Sanjay K., Bush, Kevin T., Bhatnagar, Vibha, Poloyac, Samuel M., Momper, Jeremiah D.
Publicado 2020

A pilot study on the impact of dopamine, serotonin, and brain-derived neurotrophic factor genotype on long-term functional outcomes after subarachnoid hemorrhage

por Stanfill, Ansley, Simpson, Claire, Sherwood, Paula, Poloyac, Samuel, Crago, Elizabeth, Kim, Hyungsuk, Conley, Yvette
Publicado 2017

Misreporting of contraceptive hormone use in clinical research participants

por Achilles, Sharon L., Mhlanga, Felix G., Musara, Petina, Poloyac, Samuel M., Chirenje, Zvavahera M., Hillier, Sharon L.
Publicado 2018

ABCB1 Genotype is Associated with Fentanyl Requirements in Critically Ill Children

por Horvat, Christopher M., Au, Alicia K., Conley, Yvette L., Kochanek, Patrick M., Li, Lingjue, Poloyac, Samuel L., Empey, Philip E., Clark, Robert S. B.
Publicado 2017

Iron homeostasis pathway DNA methylation trajectories reveal a role for STEAP3 metalloreductase in patient outcomes after aneurysmal subarachnoid hemorrhage

por Heinsberg, Lacey W., Weeks, Daniel E., Alexander, Sheila A., Minster, Ryan L., Sherwood, Paula R., Poloyac, Samuel M., Deslouches, Sandra, Crago, Elizabeth A., Conley, Yvette P.
Publicado 2021

ANGPT1 methylation and delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage patients

por Liu, Dongjing, Arockiaraj, Annie I., Shaffer, John R., Poloyac, Samuel M., Sherwood, Paula R., Alexander, Sheila A., Crago, Elizabeth A., Weeks, Daniel E., Conley, Yvette P.
Publicado 2021

Sensitizing Triple Negative Breast Cancer to Tamoxifen Chemotherapy via a Redox-Responsive Vorinostat-containing Polymeric Prodrug Nanocarrier

por Ma, Weina, Sun, Jingjing, Xu, Jieni, Luo, Zhangyi, Diao, Dingwei, Zhang, Ziqian, Oberly, Patrick J., Minnigh, Margaret Beth, Xie, Wen, Poloyac, Samuel M, Huang, Yi, Li, Song
Publicado 2020

Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children

por Clark, Robert S. B., Empey, Philip E., Bayır, Hülya, Rosario, Bedda L., Poloyac, Samuel M., Kochanek, Patrick M., Nolin, Thomas D., Au, Alicia K., Horvat, Christopher M., Wisniewski, Stephen R., Bell, Michael J.
Publicado 2017

Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond

por Kochanek, Patrick M., Dixon, C. Edward, Mondello, Stefania, Wang, Kevin K. K., Lafrenaye, Audrey, Bramlett, Helen M., Dietrich, W. Dalton, Hayes, Ronald L., Shear, Deborah A., Gilsdorf, Janice S., Catania, Michael, Poloyac, Samuel M., Empey, Philip E., Jackson, Travis C., Povlishock, John T.
Publicado 2018

The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease

por Schuck, Robert N., Zha, Weibin, Edin, Matthew L., Gruzdev, Artiom, Vendrov, Kimberly C., Miller, Tricia M., Xu, Zhenghong, Lih, Fred B., DeGraff, Laura M., Tomer, Kenneth B., Jones, H. Michael, Makowski, Liza, Huang, Leaf, Poloyac, Samuel M., Zeldin, Darryl C., Lee, Craig R.
Publicado 2014

mitochondrial pathway for biosynthesis of lipid mediators

por Tyurina, Yulia Y., Poloyac, Samuel M., Tyurin, Vladimir A., Kapralov, Alexander A., Jiang, Jianfei, Anthonymuthu, Tamil Selvan, Kapralova, Valentina I., Vikulina, Anna S., Jung, Mi-Yeon, Epperly, Michael W., Mohammadyani, Dariush, Klein-Seetharaman, Judith, Jackson, Travis C., Kochanek, Patrick M., Pitt, Bruce R., Greenberger, Joel S., Vladimirov, Yury A., Bayır, Hülya, Kagan, Valerian E.
Publicado 2014

Modulation of brain cation-Cl(−) cotransport via the SPAK kinase inhibitor ZT-1a

por Zhang, Jinwei, Bhuiyan, Mohammad Iqbal H., Zhang, Ting, Karimy, Jason K., Wu, Zhijuan, Fiesler, Victoria M., Zhang, Jingfang, Huang, Huachen, Hasan, Md Nabiul, Skrzypiec, Anna E., Mucha, Mariusz, Duran, Daniel, Huang, Wei, Pawlak, Robert, Foley, Lesley M., Hitchens, T. Kevin, Minnigh, Margaret B., Poloyac, Samuel M., Alper, Seth L., Molyneaux, Bradley J., Trevelyan, Andrew J., Kahle, Kristopher T., Sun, Dandan, Deng, Xianming
Publicado 2020