Destroying the androgen receptor (AR)-potential strategy to treat advanced prostate cancer

por Narayanan, Ramesh, Ponnusamy, Suriyan, Miller, Duane D.
Publicado 2017

Therapeutic advances in hormone-dependent cancers: focus on prostate, breast and ovarian cancers

por Ulm, Michael, Ramesh, Arvind V, McNamara, Keely M, Ponnusamy, Suriyan, Sasano, Hironobu, Narayanan, Ramesh
Publicado 2019

Concerted functions of HDAC1 and microRNA-574-5p repress alternatively spliced ceramide synthase 1 expression in human cancer cells

por Meyers-Needham, Marisa, Ponnusamy, Suriyan, Gencer, Salih, Jiang, Wenhui, Thomas, Raquela J, Senkal, Can E, Ogretmen, Besim
Publicado 2012

An Overview of Next-Generation Androgen Receptor-Targeted Therapeutics in Development for the Treatment of Prostate Cancer

por Mohler, Michael L., Sikdar, Arunima, Ponnusamy, Suriyan, Hwang, Dong-Jin, He, Yali, Miller, Duane D., Narayanan, Ramesh
Publicado 2021

Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis

por Ponnusamy, Suriyan, Selvam, Shanmugam Panneer, Mehrotra, Shikhar, Kawamori, Toshihiko, Snider, Ashley J, Obeid, Lina M, Shao, Yuan, Sabbadini, Roger, Ogretmen, Besim
Publicado 2012

Integrin-Linked Kinase Is a Novel Therapeutic Target in Ovarian Cancer

por Ulm, Michael A., Redfern, Tiffany M., Wilson, Ben R., Ponnusamy, Suriyan, Asemota, Sarah, Blackburn, Patrick W., Wang, Yinan, ElNaggar, Adam C., Narayanan, Ramesh
Publicado 2020

ABL1-dependent OTULIN phosphorylation promotes genotoxic Wnt/β-catenin activation to enhance drug resistance in breast cancers

por Wang, Wei, Li, Mingqi, Ponnusamy, Suriyan, Chi, Yayun, Xue, Jingyan, Fahmy, Beshoy, Fan, Meiyun, Miranda-Carboni, Gustavo A., Narayanan, Ramesh, Wu, Jiong, Wu, Zhao-Hui
Publicado 2020

Racial Differences in Androgen Receptor (AR) and AR Splice Variants (AR-SVs) Expression in Treatment-Naïve Androgen-Dependent Prostate Cancer

por Khan, Farhan, Anelo, Obianuju Mercy, Sadiq, Qandeel, Effah, Wendy, Price, Gary, Johnson, Daniel L., Ponnusamy, Suriyan, Grimes, Brandy, Morrison, Michelle L., Fowke, Jay H., Hayes, D. Neil, Narayanan, Ramesh
Publicado 2023

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

por Sentelle, R. David, Senkal, Can E., Jiang, Wenhui, Ponnusamy, Suriyan, Gencer, Salih, Selvam, Shanmugam Panneer, Ramshesh, Venkat K., Peterson, Yuri K., Lemasters, John J., Szulc, Zdzislaw M., Bielawski, Jacek, Ogretmen, Besim
Publicado 2012

Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer

por Thiyagarajan, Thirumagal, Ponnusamy, Suriyan, Hwang, Dong-Jin, He, Yali, Asemota, Sarah, Young, Kirsten L., Johnson, Daniel L., Bocharova, Vera, Zhou, Weidong, Jain, Abhinav K., Petricoin, Emanuel F., Yin, Zheng, Pfeffer, Lawrence M., Miller, Duane D., Narayanan, Ramesh
Publicado 2022

Androgen Receptor Is a Non-canonical Inhibitor of Wild-Type and Mutant Estrogen Receptors in Hormone Receptor-Positive Breast Cancers

por Ponnusamy, Suriyan, Asemota, Sarah, Schwartzberg, Lee S., Guestini, Fouzia, McNamara, Keely M., Pierobon, Mariaelena, Font-Tello, Alba, Qiu, Xintao, Xie, Yingtian, Rao, Prakash K., Thiyagarajan, Thirumagal, Grimes, Brandy, Johnson, Daniel L., Fleming, Martin D., Pritchard, Frances E., Berry, Michael P., Oswaks, Roy, Fine, Richard E., Brown, Myles, Sasano, Hironobu, Petricoin, Emanuel F., Long, Henry W., Narayanan, Ramesh
Publicado 2019