Structure-PPi: a module for the annotation of cancer-related single-nucleotide variants at protein–protein interfaces

por Vázquez, Miguel, Valencia, Alfonso, Pons, Tirso
Publicado 2015

Computational Biology in Cuba: An Opportunity to Promote Science in a Developing Country

por Pons, Tirso, Montero, Luis A, Febles, Juan P
Publicado 2007

Functional analysis of archaeal MBF1 by complementation studies in yeast

por Marrero Coto, Jeannette, Ehrenhofer-Murray, Ann E, Pons, Tirso, Siebers, Bettina
Publicado 2011

Computational Perspectives into Plasmepsins Structure—Function Relationship: Implications to Inhibitors Design

por Gil L., Alejandro, Valiente, Pedro A., Pascutti, Pedro G., Pons, Tirso
Publicado 2011

A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases

por Magraner-Pardo, Lorena, Laskowski, Roman A., Pons, Tirso, Thornton, Janet M.
Publicado 2021

Systematic Analysis of FASTK Gene Family Alterations in Cancer

por Magraner-Pardo, Lorena, Gobelli, Dino, de la Fuente, Miguel A., Pons, Tirso, Simarro, María
Publicado 2021

KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily

por Pons, Tirso, Vazquez, Miguel, Matey-Hernandez, María Luisa, Brunak, Søren, Valencia, Alfonso, Izarzugaza, Jose MG
Publicado 2016

Poorly Conserved P15 Proteins of Cileviruses Retain Elements of Common Ancestry and Putative Functionality: A Theoretical Assessment on the Evolution of Cilevirus Genomes

por Ramos-González, Pedro L., Pons, Tirso, Chabi-Jesus, Camila, Arena, Gabriella Dias, Freitas-Astua, Juliana
Publicado 2021

The Kunitz-Type Protein ShPI-1 Inhibits Serine Proteases and Voltage-Gated Potassium Channels

por García-Fernández, Rossana, Peigneur, Steve, Pons, Tirso, Alvarez, Carlos, González, Lidice, Chávez, María A., Tytgat, Jan
Publicado 2016

Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels

por Fütterer, Agnes, Talavera-Gutiérrez, Amaia, Pons, Tirso, de Celis, Jesús, Gutiérrez, Julio, Domínguez Plaza, Verónica, Martínez-A, Carlos
Publicado 2021

Lack of evidence for germline WWP1 pathogenic variants in gastrointestinal polyposis and other phenotypes suggestive of PTEN-hamartoma-tumor syndrome

por Gonzalez-Abuin, Noemi, Pons, Tirso, Fuster, Teresa, Quintana, Isabel, Terradas, Mariona, Aiza, Gemma, Brunet, Joan, Capellá, Gabriel, Hampel, Heather, Valle, Laura
Publicado 2023

Geleophysic dysplasia: novel missense variants and insights into ADAMTSL2 intracellular trafficking

por Piccolo, Pasquale, Sabatino, Valeria, Mithbaokar, Pratibha, Polishchuck, Elena, Law, Simon K., Magraner-Pardo, Lorena, Pons, Tirso, Polishchuck, Roman, Brunetti-Pierri, Nicola
Publicado 2019

Recommendations for the classification of germline variants in the exonuclease domain of POLE and POLD1

por Mur, Pilar, Viana-Errasti, Julen, García-Mulero, Sandra, Magraner-Pardo, Lorena, Muñoz, Inés G., Pons, Tirso, Capellá, Gabriel, Pineda, Marta, Feliubadaló, Lidia, Valle, Laura
Publicado 2023

KSR induces RAS‐independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors

por Paniagua, Guillem, Jacob, Harrys K.C., Brehey, Oksana, García‐Alonso, Sara, Lechuga, Carmen G., Pons, Tirso, Musteanu, Monica, Guerra, Carmen, Drosten, Matthias, Barbacid, Mariano
Publicado 2022

PhcrTx2, a New Crab-Paralyzing Peptide Toxin from the Sea Anemone Phymanthus crucifer

por Rodríguez, Armando Alexei, Garateix, Anoland, Salceda, Emilio, Peigneur, Steve, Zaharenko, André Junqueira, Pons, Tirso, Santos, Yúlica, Arreguín, Roberto, Ständker, Ludger, Forssmann, Wolf-Georg, Tytgat, Jan, Vega, Rosario, Soto, Enrique
Publicado 2018

POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance

por Bellido, Fernando, Pineda, Marta, Aiza, Gemma, Valdés-Mas, Rafael, Navarro, Matilde, Puente, Diana A., Pons, Tirso, González, Sara, Iglesias, Silvia, Darder, Esther, Piñol, Virginia, Soto, José Luís, Valencia, Alfonso, Blanco, Ignacio, Urioste, Miguel, Brunet, Joan, Lázaro, Conxi, Capellá, Gabriel, Puente, Xose S., Valle, Laura
Publicado 2016

Brain radiotoxicity-related 15CAcBRT gene expression signature predicts survival prognosis of glioblastoma patients

por Reyes-González, Jesús, Barajas-Olmos, Francisco, García-Ortiz, Humberto, Magraner-Pardo, Lorena, Pons, Tirso, Moreno, Sergio, Aguirre-Cruz, Lucinda, Reyes-Abrahantes, Andy, Martínez-Hernández, Angélica, Contreras-Cubas, Cecilia, Barrios-Payan, Jorge, Ruiz-Garcia, Henry, Hernandez-Pando, Rogelio, Quiñones-Hinojosa, Alfredo, Orozco, Lorena, Abrahantes-Pérez, María del Carmen
Publicado 2022

Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis

por Mur, Pilar, De Voer, Richarda M., Olivera-Salguero, Rubén, Rodríguez-Perales, Sandra, Pons, Tirso, Setién, Fernando, Aiza, Gemma, Valdés-Mas, Rafael, Bertini, Angelo, Pineda, Marta, Vreede, Lilian, Navarro, Matilde, Iglesias, Silvia, González, Sara, Brunet, Joan, Valencia, Alfonso, Esteller, Manel, Lázaro, Conxi, Kops, Geert J. P. L., Urioste, Miguel, Puente, Xose S., Capellá, Gabriel, Valle, Laura
Publicado 2018

Role of POLE and POLD1 in familial cancer

por Mur, Pilar, García-Mulero, Sandra, del Valle, Jesús, Magraner-Pardo, Lorena, Vidal, August, Pineda, Marta, Cinnirella, Giacomo, Martín-Ramos, Edgar, Pons, Tirso, López-Doriga, Adriana, Belhadj, Sami, Feliubadaló, Lidia, Munoz-Torres, Pau M., Navarro, Matilde, Grau, Elia, Darder, Esther, Llort, Gemma, Sanz, Judit, Ramón y Cajal, Teresa, Balmana, Judith, Brunet, Joan, Moreno, Victor, Piulats, Josep M., Matías-Guiu, Xavier, Sanz-Pamplona, Rebeca, Aligué, Rosa, Capellá, Gabriel, Lázaro, Conxi, Valle, Laura
Publicado 2020