Targeting MYCN and ALK in resistant and relapsing neuroblastoma

por Tucker, Elizabeth R, Poon, Evon, Chesler, Louis
Publicado 2019

The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme

por Urban-Wójciuk, Zuzanna, Graham, Amy, Barker, Karen, Kwok, Colin, Sbirkov, Yordan, Howell, Louise, Campbell, James, Woster, Patrick M., Poon, Evon, Petrie, Kevin, Chesler, Louis
Publicado 2021

Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus

por Gonzalez Malagon, Sandra G., Lopez Muñoz, Anna M., Doro, Daniel, Bolger, Triòna G., Poon, Evon, Tucker, Elizabeth R., Adel Al-Lami, Hadeel, Krause, Matthias, Phiel, Christopher J., Chesler, Louis, Liu, Karen J.
Publicado 2018

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

por King, David, Li, Xiao Dun, Almeida, Gilberto S., Kwok, Colin, Gravells, Polly, Harrison, Daniel, Burke, Saoirse, Hallsworth, Albert, Jamin, Yann, George, Sally, Robinson, Simon P., Lord, Christopher J., Poon, Evon, Yeomanson, Daniel, Chesler, Louis, Bryant, Helen E.
Publicado 2020

Correction: MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

por King, David, Li, Xiao Dun, Almeida, Gilberto S., Kwok, Colin, Gravells, Polly, Harrison, Daniel, Burke, Saoirse, Hallsworth, Albert, Jamin, Yann, George, Sally, Robinson, Simon P., Lord, Christopher J., Poon, Evon, Yeomanson, Daniel, Chesler, Louis, Bryant, Helen E.
Publicado 2023

MYC regulates metabolism through vesicular transfer of glycolytic kinases

por Tsakaneli, Alexia, Carregari, Victor Corasolla, Morini, Martina, Eva, Alessandra, Cangemi, Giuliana, Chayka, Olesya, Makarov, Evgeny, Bibbò, Sandra, Capone, Emily, Sala, Gianluca, De Laurenzi, Vincenzo, Poon, Evon, Chesler, Louis, Pieroni, Luisa, Larsen, Martin R., Palmisano, Giuseppe, Sala, Arturo
Publicado 2021

Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle

por Büchel, Gabriele, Carstensen, Anne, Mak, Ka-Yan, Roeschert, Isabelle, Leen, Eoin, Sumara, Olga, Hofstetter, Julia, Herold, Steffi, Kalb, Jacqueline, Baluapuri, Apoorva, Poon, Evon, Kwok, Colin, Chesler, Louis, Maric, Hans Michael, Rickman, David S., Wolf, Elmar, Bayliss, Richard, Walz, Susanne, Eilers, Martin
Publicado 2017

Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma

por Nijhuis, Anke, Sikka, Arti, Yogev, Orli, Herendi, Lili, Balcells, Cristina, Ma, Yurui, Poon, Evon, Eckold, Clare, Valbuena, Gabriel N., Xu, Yuewei, Liu, Yusong, da Costa, Barbara Martins, Gruet, Michael, Wickremesinghe, Chiharu, Benito, Adrian, Kramer, Holger, Montoya, Alex, Carling, David, Want, Elizabeth J., Jamin, Yann, Chesler, Louis, Keun, Hector C.
Publicado 2022

Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease

por Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet C., Petrie, Kevin, Schwalbe, Ed C., Barker, Karen, Boult, Jessica K.R., Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L., Poon, Evon, Robinson, Simon P., Ruddle, Ruth, Raynaud, Florence I., Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W., Wharton, Stephen B., Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S., Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Weiss, William A., Chesler, Louis, Clifford, Steven C.
Publicado 2015

Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models

por Tucker, Elizabeth R., Jiménez, Irene, Chen, Lindi, Bellini, Angela, Gorrini, Chiara, Calton, Elizabeth, Gao, Qiong, Che, Harvey, Poon, Evon, Jamin, Yann, Martins Da Costa, Barbara, Barker, Karen, Shrestha, Sumana, Hutchinson, J. Ciaran, Dhariwal, Simran, Goodman, Angharad, Del Nery, Elaine, Gestraud, Pierre, Bhalshankar, Jaydutt, Iddir, Yasmine, Saberi-Ansari, Elnaz, Saint-Charles, Alexandra, Geoerger, Birgit, Marques Da Costa, Maria Eugénia, Pierre-Eugène, Cécile, Janoueix-Lerosey, Isabelle, Decaudin, Didier, Nemati, Fariba, Carcaboso, Angel M., Surdez, Didier, Delattre, Olivier, George, Sally L., Chesler, Louis, Tweddle, Deborah A., Schleiermacher, Gudrun
Publicado 2023

Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma

por Poon, Evon, Liang, Tong, Jamin, Yann, Walz, Susanne, Kwok, Colin, Hakkert, Anne, Barker, Karen, Urban, Zuzanna, Thway, Khin, Zeid, Rhamy, Hallsworth, Albert, Box, Gary, Ebus, Marli E., Licciardello, Marco P., Sbirkov, Yordan, Lazaro, Glori, Calton, Elizabeth, Costa, Barbara M., Valenti, Melanie, De Haven Brandon, Alexis, Webber, Hannah, Tardif, Nicolas, Almeida, Gilberto S., Christova, Rossitza, Boysen, Gunther, Richards, Mark W., Barone, Giuseppe, Ford, Anthony, Bayliss, Richard, Clarke, Paul A., De Bono, Johann, Gray, Nathanael S., Blagg, Julian, Robinson, Simon P., Eccles, Suzanne A., Zheleva, Daniella, Bradner, James E., Molenaar, Jan, Vivanco, Igor, Eilers, Martin, Workman, Paul, Lin, Charles Y., Chesler, Louis
Publicado 2020