Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival

por Hughson, Luke R. K., Poon, Vincent I., Spowart, Jaeline E., Lum, Julian J.
Publicado 2012

Ganglioside GD2 expression is maintained upon recurrence in patients with osteosarcoma

por Poon, Vincent I, Roth, Michael, Piperdi, Sajida, Geller, David, Gill, Jonathan, Rudzinski, Erin R, Hawkins, Douglas S, Gorlick, Richard
Publicado 2015

Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex

por Siu, Kam-Leung, Kok, Kin-Hang, Ng, Ming-Him James, Poon, Vincent K. M., Yuen, Kwok-Yung, Zheng, Bo-Jian, Jin, Dong-Yan
Publicado 2009

A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

por Zhao, Guangyu, Du, Lanying, Ma, Cuiqing, Li, Ye, Li, Lin, Poon, Vincent KM, Wang, Lili, Yu, Fei, Zheng, Bo-Jian, Jiang, Shibo, Zhou, Yusen
Publicado 2013

An H5N1-based matrix protein 2 ectodomain tetrameric peptide vaccine provides cross-protection against lethal infection with H7N9 influenza virus

por Leung, Ho-Chuen, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Zhao, Han-Jun, Cheung, Chung-Yan, Ng, Fai, Huang, Jian-Dong, Zheng, Bo-Jian
Publicado 2015

A Recombinant Vaccine of H5N1 HA1 Fused with Foldon and Human IgG Fc Induced Complete Cross-Clade Protection against Divergent H5N1 Viruses

por Du, Lanying, Leung, Virtual Ho-Chuen, Zhang, Xiujuan, Zhou, Jie, Chen, Min, He, Wu, Zhang, Hai-Ying, Chan, Chris C. S., Poon, Vincent Kwok-Man, Zhao, Guangyu, Sun, Shihui, Cai, Lifeng, Zhou, Yusen, Zheng, Bo-Jian, Jiang, Shibo
Publicado 2011

SPINK6 inhibits human airway serine proteases and restricts influenza virus activation

por Wang, Dong, Li, Cun, Chiu, Man Chun, Yu, Yifei, Liu, Xiaojuan, Zhao, Xiaoyu, Huang, Jingjing, Cheng, Zhongshan, Yuan, Shuofeng, Poon, Vincent, Cai, Jian‐Piao, Chu, Hin, Chan, Jasper Fuk‐Woo, To, Kelvin Kai‐Wang, Yuen, Kwok Yung, Zhou, Jie
Publicado 2021

A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses

por Zhao, Hanjun, Zhou, Jie, Zhang, Ke, Chu, Hin, Liu, Dabin, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Leung, Ho-Chuen, Fai, Ng, Lin, Yong-Ping, Zhang, Anna Jin-Xia, Jin, Dong-Yan, Yuen, Kwok-Yung, Zheng, Bo-Jian
Publicado 2016

Identification and characterization of GLDC as host susceptibility gene to severe influenza

por Zhou, Jie, Wang, Dong, Wong, Bosco Ho‐Yin, Li, Cun, Poon, Vincent Kwok‐Man, Wen, Lei, Zhao, Xiaoyu, Chiu, Man Chun, Liu, Xiaojuan, Ye, Ziwei, Yuan, Shuofeng, Sze, Kong‐Hung, Chan, Jasper Fuk‐Woo, Chu, Hin, To, Kelvin Kai‐Wang, Yuen, Kwok Yung
Publicado 2018

Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response

por Chu, Hin, Zhou, Jie, Ho-Yin Wong, Bosco, Li, Cun, Cheng, Zhong-Shan, Lin, Xiang, Kwok-Man Poon, Vincent, Sun, Tianhao, Choi-Yi Lau, Candy, Fuk-Woo Chan, Jasper, Kai-Wang To, Kelvin, Chan, Kwok-Hung, Lu, Liwei, Zheng, Bo-Jian, Yuen, Kwok-Yung
Publicado 2014

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters

por Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Jasper Fuk-Woo, Liu, Feifei, Li, Can, Chen, Yanxia, Chu, Hin, Lau, Siu-Ying, Wang, Pui, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yuan, Shuofeng, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung
Publicado 2020

A small animal model of chronic hepatitis E infection using immunocompromised rats

por Sridhar, Siddharth, Wu, Shusheng, Situ, Jianwen, Shun, Estie Hon-Kiu, Li, Zhiyu, Zhang, Anna Jin-Xia, Hui, Kyle, Fong, Carol Ho-Yan, Poon, Vincent Kwok-Man, Chew, Nicholas Foo-Siong, Yip, Cyril Chik-Yan, Chan, Wan-Mui, Cai, Jian-Piao, Yuen, Kwok-Yung
Publicado 2022

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targe...

por Chan, Jasper Fuk-Woo, Zhu, Zheng, Chu, Hin, Yuan, Shuofeng, Chik, Kenn Ka-Heng, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yip, Cyril Chik-Yan, Zhang, Xi, Tsang, Jessica Oi-Ling, Zou, Zijiao, Tee, Kah-Meng, Shuai, Huiping, Lu, Gang, Yuen, Kwok-Yung
Publicado 2018

P21-activated kinase 1 (PAK1)-mediated cytoskeleton rearrangement promotes SARS-CoV-2 entry and ACE2 autophagic degradation

por Liu, Ming, Lu, Bingtai, Li, Yue, Yuan, Shuofeng, Zhuang, Zhen, Li, Guangyu, Wang, Dong, Ma, Liuheyi, Zhu, Jianheng, Zhao, Jinglu, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Chik, Kenn Ka-Heng, Zhao, Zhiyao, Xian, Huifang, Zhao, Jingxian, Zhao, Jincun, Chan, Jasper Fuk-Woo, Zhang, Yuxia
Publicado 2023

Differentiated human airway organoids to assess infectivity of emerging influenza virus

por Zhou, Jie, Li, Cun, Sachs, Norman, Chiu, Man Chun, Wong, Bosco Ho-Yin, Chu, Hin, Poon, Vincent Kwok-Man, Wang, Dong, Zhao, Xiaoyu, Wen, Lei, Song, Wenjun, Yuan, Shuofeng, Wong, Kenneth Kak-Yuen, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Honglin, Clevers, Hans, Yuen, Kwok-Yung
Publicado 2018

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters

por Lee, Andrew Chak-Yiu, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Li, Can, Fan, Zhimeng, Liu, Feifei, Chen, Yanxia, Liang, Ronghui, Sridhar, Siddharth, Cai, Jian-Piao, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, To, Kelvin Kai-Wang, Yuan, Shuofeng, Zhou, Jie, Chu, Hin, Yuen, Kwok-Yung
Publicado 2020

Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection

por Ye, Zi-Wei, Yuan, Shuofeng, Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Yu, Ching-Yun, Ong, Chon Phin, Yang, Dong, Chan, Chris Chun-Yiu, Tang, Kaiming, Cao, Jianli, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Cai, Jian-Piao, Chu, Hin, Yuen, Kwok-Yung, Jin, Dong-Yan
Publicado 2021

Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking

por Liu, Lihong, Casner, Ryan G., Guo, Yicheng, Wang, Qian, Iketani, Sho, Chan, Jasper Fuk-Woo., Yu, Jian, Dadonaite, Bernadeta, Nair, Manoj S., Mohri, Hiroshi, Reddem, Eswar R., Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Yuen, Kwok-Yung, Sheng, Zizhang, Huang, Yaoxing, Bloom, Jesse D., Shapiro, Lawrence, Ho, David D.
Publicado 2023

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target

por Yuan, Shuofeng, Chu, Hin, Huang, Jingjing, Zhao, Xiaoyu, Ye, Zi-Wei, Lai, Pok-Man, Wen, Lei, Cai, Jian-Piao, Mo, Yufei, Cao, Jianli, Liang, Ronghui, Poon, Vincent Kwok-Man, Sze, Kong-Hung, Zhou, Jie, To, Kelvin Kai-Wang, Chen, Zhiwei, Chen, Honglin, Jin, Dong-Yan, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Publicado 2020

Wild Type and Mutant 2009 Pandemic Influenza A (H1N1) Viruses Cause More Severe Disease and Higher Mortality in Pregnant BALB/c Mice

por Chan, Kwok-Hung, Zhang, Anna J. X., To, Kelvin K. W., Chan, Chris C. S., Poon, Vincent K. M., Guo, Kunyuan, Ng, Fai, Zhang, Qi-Wei, Leung, Virtual H. C., Cheung, Annie N. Y., Lau, Candy C. Y., Woo, Patrick C. Y., Tse, Herman, Wu, Wailan, Chen, Honglin, Zheng, Bo-Jian, Yuen, Kwok-Yung
Publicado 2010