An H5N1-based matrix protein 2 ectodomain tetrameric peptide vaccine provides cross-protection against lethal infection with H7N9 influenza virus

por Leung, Ho-Chuen, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Zhao, Han-Jun, Cheung, Chung-Yan, Ng, Fai, Huang, Jian-Dong, Zheng, Bo-Jian
Publicado 2015

A Recombinant Vaccine of H5N1 HA1 Fused with Foldon and Human IgG Fc Induced Complete Cross-Clade Protection against Divergent H5N1 Viruses

por Du, Lanying, Leung, Virtual Ho-Chuen, Zhang, Xiujuan, Zhou, Jie, Chen, Min, He, Wu, Zhang, Hai-Ying, Chan, Chris C. S., Poon, Vincent Kwok-Man, Zhao, Guangyu, Sun, Shihui, Cai, Lifeng, Zhou, Yusen, Zheng, Bo-Jian, Jiang, Shibo
Publicado 2011

A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses

por Zhao, Hanjun, Zhou, Jie, Zhang, Ke, Chu, Hin, Liu, Dabin, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Leung, Ho-Chuen, Fai, Ng, Lin, Yong-Ping, Zhang, Anna Jin-Xia, Jin, Dong-Yan, Yuen, Kwok-Yung, Zheng, Bo-Jian
Publicado 2016

Identification and characterization of GLDC as host susceptibility gene to severe influenza

por Zhou, Jie, Wang, Dong, Wong, Bosco Ho‐Yin, Li, Cun, Poon, Vincent Kwok‐Man, Wen, Lei, Zhao, Xiaoyu, Chiu, Man Chun, Liu, Xiaojuan, Ye, Ziwei, Yuan, Shuofeng, Sze, Kong‐Hung, Chan, Jasper Fuk‐Woo, Chu, Hin, To, Kelvin Kai‐Wang, Yuen, Kwok Yung
Publicado 2018

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters

por Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Jasper Fuk-Woo, Liu, Feifei, Li, Can, Chen, Yanxia, Chu, Hin, Lau, Siu-Ying, Wang, Pui, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yuan, Shuofeng, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung
Publicado 2020

A small animal model of chronic hepatitis E infection using immunocompromised rats

por Sridhar, Siddharth, Wu, Shusheng, Situ, Jianwen, Shun, Estie Hon-Kiu, Li, Zhiyu, Zhang, Anna Jin-Xia, Hui, Kyle, Fong, Carol Ho-Yan, Poon, Vincent Kwok-Man, Chew, Nicholas Foo-Siong, Yip, Cyril Chik-Yan, Chan, Wan-Mui, Cai, Jian-Piao, Yuen, Kwok-Yung
Publicado 2022

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targe...

por Chan, Jasper Fuk-Woo, Zhu, Zheng, Chu, Hin, Yuan, Shuofeng, Chik, Kenn Ka-Heng, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yip, Cyril Chik-Yan, Zhang, Xi, Tsang, Jessica Oi-Ling, Zou, Zijiao, Tee, Kah-Meng, Shuai, Huiping, Lu, Gang, Yuen, Kwok-Yung
Publicado 2018

P21-activated kinase 1 (PAK1)-mediated cytoskeleton rearrangement promotes SARS-CoV-2 entry and ACE2 autophagic degradation

por Liu, Ming, Lu, Bingtai, Li, Yue, Yuan, Shuofeng, Zhuang, Zhen, Li, Guangyu, Wang, Dong, Ma, Liuheyi, Zhu, Jianheng, Zhao, Jinglu, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Chik, Kenn Ka-Heng, Zhao, Zhiyao, Xian, Huifang, Zhao, Jingxian, Zhao, Jincun, Chan, Jasper Fuk-Woo, Zhang, Yuxia
Publicado 2023

Differentiated human airway organoids to assess infectivity of emerging influenza virus

por Zhou, Jie, Li, Cun, Sachs, Norman, Chiu, Man Chun, Wong, Bosco Ho-Yin, Chu, Hin, Poon, Vincent Kwok-Man, Wang, Dong, Zhao, Xiaoyu, Wen, Lei, Song, Wenjun, Yuan, Shuofeng, Wong, Kenneth Kak-Yuen, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Honglin, Clevers, Hans, Yuen, Kwok-Yung
Publicado 2018

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters

por Lee, Andrew Chak-Yiu, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Li, Can, Fan, Zhimeng, Liu, Feifei, Chen, Yanxia, Liang, Ronghui, Sridhar, Siddharth, Cai, Jian-Piao, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, To, Kelvin Kai-Wang, Yuan, Shuofeng, Zhou, Jie, Chu, Hin, Yuen, Kwok-Yung
Publicado 2020

Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection

por Ye, Zi-Wei, Yuan, Shuofeng, Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Yu, Ching-Yun, Ong, Chon Phin, Yang, Dong, Chan, Chris Chun-Yiu, Tang, Kaiming, Cao, Jianli, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Cai, Jian-Piao, Chu, Hin, Yuen, Kwok-Yung, Jin, Dong-Yan
Publicado 2021

Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking

por Liu, Lihong, Casner, Ryan G., Guo, Yicheng, Wang, Qian, Iketani, Sho, Chan, Jasper Fuk-Woo., Yu, Jian, Dadonaite, Bernadeta, Nair, Manoj S., Mohri, Hiroshi, Reddem, Eswar R., Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Yuen, Kwok-Yung, Sheng, Zizhang, Huang, Yaoxing, Bloom, Jesse D., Shapiro, Lawrence, Ho, David D.
Publicado 2023

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target

por Yuan, Shuofeng, Chu, Hin, Huang, Jingjing, Zhao, Xiaoyu, Ye, Zi-Wei, Lai, Pok-Man, Wen, Lei, Cai, Jian-Piao, Mo, Yufei, Cao, Jianli, Liang, Ronghui, Poon, Vincent Kwok-Man, Sze, Kong-Hung, Zhou, Jie, To, Kelvin Kai-Wang, Chen, Zhiwei, Chen, Honglin, Jin, Dong-Yan, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Publicado 2020

SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters

por Qiao, Wei, Lau, Hui En, Xie, Huizhi, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Chu, Hin, Yuan, Shuofeng, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Yuen, Kwok-Yung, Cheung, Kenneth Man-Chee, Chan, Jasper Fuk-Woo, Yeung, Kelvin Wai-Kwok
Publicado 2022

Author Correction: SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters

por Qiao, Wei, Lau, Hui En, Xie, Huizhi, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Chu, Hin, Yuan, Shuofeng, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Yuen, Kwok-Yung, Cheung, Kenneth Man-Chee, Chan, Jasper Fuk-Woo, Yeung, Kelvin Wai-Kwok
Publicado 2022

Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells

por Chu, Hin, Chan, Che-Man, Zhang, Xi, Wang, Yixin, Yuan, Shuofeng, Zhou, Jie, Au-Yeung, Rex Kwok-Him, Sze, Kong-Hung, Yang, Dong, Shuai, Huiping, Hou, Yuxin, Li, Cun, Zhao, Xiaoyu, Poon, Vincent Kwok-Man, Leung, Sze Pui, Yeung, Man-Lung, Yan, Jinghua, Lu, Guangwen, Jin, Dong-Yan, Gao, George Fu, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Publicado 2018

The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage

por Liang, Ronghui, Ye, Zi-Wei, Ong, Chon Phin, Qin, Zhenzhi, Xie, Yubin, Fan, Yilan, Tang, Kaiming, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Yang, Xiaomeng, Cao, Hehe, Wang, Kun, Sun, Haoran, Hu, Bodan, Cai, Jian-Piao, Luo, Cuiting, Chik, Kenn Ka-Heng, Chu, Hin, Zheng, Yi, Yuen, Kwok-Yung, Chan, Jasper Fuk-Woo, Jin, Dong-Yan, Yuan, Shuofeng
Publicado 2022

Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant...

por Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Chan, Chris Chung-Sing, Yip, Cyril Chik-Yan, Mak, Winger Wing-Nga, Zhu, Houshun, Poon, Vincent Kwok-Man, Tee, Kah-Meng, Zhu, Zheng, Cai, Jian-Piao, Tsang, Jessica Oi-Ling, Chik, Kenn Ka-Heng, Yin, Feifei, Chan, Kwok-Hung, Kok, Kin-Hang, Jin, Dong-Yan, Au-Yeung, Rex Kwok-Him, Yuen, Kwok-Yung
Publicado 2016

A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge

por Zhou, Biao, Zhou, Runhong, Tang, Bingjie, Chan, Jasper Fuk-Woo, Luo, Mengxiao, Peng, Qiaoli, Yuan, Shuofeng, Liu, Hang, Mok, Bobo Wing-Yee, Chen, Bohao, Wang, Pui, Poon, Vincent Kwok-Man, Chu, Hin, Chan, Chris Chung-Sing, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Au, Ka-Kit, Man, Hiu-On, Lu, Lu, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung, Dang, Shangyu, Chen, Zhiwei
Publicado 2022

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

por Chan, Jasper Fuk-Woo, Yuan, Shuofeng, Kok, Kin-Hang, To, Kelvin Kai-Wang, Chu, Hin, Yang, Jin, Xing, Fanfan, Liu, Jieling, Yip, Cyril Chik-Yan, Poon, Rosana Wing-Shan, Tsoi, Hoi-Wah, Lo, Simon Kam-Fai, Chan, Kwok-Hung, Poon, Vincent Kwok-Man, Chan, Wan-Mui, Ip, Jonathan Daniel, Cai, Jian-Piao, Cheng, Vincent Chi-Chung, Chen, Honglin, Hui, Christopher Kim-Ming, Yuen, Kwok-Yung
Publicado 2020