Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach

por Poos, Alexandra M., Kordaß, Theresa, Kolte, Amol, Ast, Volker, Oswald, Marcus, Rippe, Karsten, König, Rainer
Publicado 2019

Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast

por Poos, Alexandra M., Maicher, André, Dieckmann, Anna K., Oswald, Marcus, Eils, Roland, Kupiec, Martin, Luke, Brian, König, Rainer
Publicado 2016

P839: GAIN OF CHROMOSOME 1Q LEADS TO HIGH EXPRESSION OF SNORD78 AND ABERRANT RIBOSOME METHYLATION

por Zhao, Duoduo, Rohde, Christian, Göllner, Stefanie, Zhou, Fengbiao, Pauli, Cornelius, Blank, Maximilian, Zinz, Rafael, Luise Grab, Anna, Poos, Alexandra M, John, Lukas, Huhn, Stefanie, Raab, Marc S., Müller-Tidow, Carsten, Weinhold, Niels
Publicado 2023

Inhibiting PI3K–AKT–mTOR Signaling in Multiple Myeloma-Associated Mesenchymal Stem Cells Impedes the Proliferation of Multiple Myeloma Cells

por Heinemann, Luca, Möllers, Klara Maria, Ahmed, Helal Mohammed Mohammed, Wei, Lanying, Sun, Kaiyan, Nimmagadda, Subbaiah Chary, Frank, Daria, Baumann, Anja, Poos, Alexandra M., Dugas, Martin, Varghese, Julian, Raab, Marc-Steffen, Khandanpour, Cyrus
Publicado 2022

The landscape of small nucleolar RNA expression in multiple myeloma is determined by cytogenetic alterations

por Zhao, Duoduo, Rohde, Christian, Göllner, Stefanie, Zhou, Fengbiao, Pauli, Cornelius, Blank, Maximilian Felix, Zinz, Rafael, Grab, Anna Luise, Poos, Alexandra M., John, Lukas, Huhn, Stefanie, Raab, Marc-Steffen, Müller-Tidow, Carsten, Weinhold, Niels
Publicado 2023

Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level

por Schinke, Carolina, Poos, Alexandra M., Bauer, Michael, John, Lukas, Johnson, Sarah, Deshpande, Shayu, Carrillo, Luis, Alapat, Daisy, Rasche, Leo, Thanendrarajan, Sharmilan, Zangari, Maurizio, Al Hadidi, Samer, van Rhee, Frits, Davies, Faith, Raab, Marc S., Morgan, Gareth, Weinhold, Niels
Publicado 2022

The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states

por Rasche, Leo, Schinke, Carolina, Maura, Francesco, Bauer, Michael A., Ashby, Cody, Deshpande, Shayu, Poos, Alexandra M., Zangari, Maurizio, Thanendrarajan, Sharmilan, Davies, Faith E., Walker, Brian A., Barlogie, Bart, Landgren, Ola, Morgan, Gareth J., van Rhee, Frits, Weinhold, Niels
Publicado 2022

Implications and prognostic impact of mass spectrometry in patients with newly-diagnosed multiple myeloma

por Mai, Elias K., Huhn, Stefanie, Miah, Kaya, Poos, Alexandra M., Scheid, Christof, Weisel, Katja C., Bertsch, Uta, Munder, Markus, Berlanga, Oscar, Hose, Dirk, Seckinger, Anja, Jauch, Anna, Blau, Igor W., Hänel, Mathias, Salwender, Hans J., Benner, Axel, Raab, Marc S., Goldschmidt, Hartmut, Weinhold, Niels
Publicado 2023

Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics

por Tirier, Stephan M., Mallm, Jan-Philipp, Steiger, Simon, Poos, Alexandra M., Awwad, Mohamed H. S., Giesen, Nicola, Casiraghi, Nicola, Susak, Hana, Bauer, Katharina, Baumann, Anja, John, Lukas, Seckinger, Anja, Hose, Dirk, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Stegle, Oliver, Hundemer, Michael, Weinhold, Niels, Raab, Marc S., Rippe, Karsten
Publicado 2021

An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma

por Darawshi, Odai, Muz, Barbara, Naamat, Shiri Gershon, Praveen, Bellam, Mahameed, Mohamed, Goldberg, Karin, Dipta, Priya, Shmuel, Miriam, Forno, Francesca, Boukeileh, Shatha, Pahima, Hadas, Hermann, Julia, Raab, Marc S., Poos, Alexandra M., Weinhold, Niels, Rosenbluh, Chaggai, Gatt, Moshe E., Palm, Wilhelm, Azab, Abdel Kareem, Tirosh, Boaz
Publicado 2022

Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks

por Mallm, Jan‐Philipp, Iskar, Murat, Ishaque, Naveed, Klett, Lara C, Kugler, Sabrina J, Muino, Jose M, Teif, Vladimir B, Poos, Alexandra M, Großmann, Sebastian, Erdel, Fabian, Tavernari, Daniele, Koser, Sandra D, Schumacher, Sabrina, Brors, Benedikt, König, Rainer, Remondini, Daniel, Vingron, Martin, Stilgenbauer, Stephan, Lichter, Peter, Zapatka, Marc, Mertens, Daniel, Rippe, Karsten
Publicado 2019

Expression of CCCTC‐binding factor (CTCF) is linked to poor prognosis in prostate cancer

por Höflmayer, Doris, Steinhoff, Amélie, Hube‐Magg, Claudia, Kluth, Martina, Simon, Ronald, Burandt, Eike, Tsourlakis, Maria Christina, Minner, Sarah, Sauter, Guido, Büscheck, Franziska, Wilczak, Waldemar, Steurer, Stefan, Huland, Hartwig, Graefen, Markus, Haese, Alexander, Heinzer, Hans, Schlomm, Thorsten, Jacobsen, Frank, Hinsch, Andrea, Poos, Alexandra M., Oswald, Marcus, Rippe, Karsten, König, Rainer, Schroeder, Cornelia
Publicado 2019

PITX1 Is a Regulator of TERT Expression in Prostate Cancer with Prognostic Power

por Poos, Alexandra M., Schroeder, Cornelia, Jaishankar, Neeraja, Röll, Daniela, Oswald, Marcus, Meiners, Jan, Braun, Delia M., Knotz, Caroline, Frank, Lukas, Gunkel, Manuel, Spilger, Roman, Wollmann, Thomas, Polonski, Adam, Makrypidi-Fraune, Georgia, Fraune, Christoph, Graefen, Markus, Chung, Inn, Stenzel, Alexander, Erfle, Holger, Rohr, Karl, Baniahmad, Aria, Sauter, Guido, Rippe, Karsten, Simon, Ronald, Koenig, Rainer
Publicado 2022

Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level

por John, Lukas, Poos, Alexandra M., Brobeil, Alexander, Schinke, Carolina, Huhn, Stefanie, Prokoph, Nina, Lutz, Raphael, Wagner, Barbara, Zangari, Maurizio, Tirier, Stephan M., Mallm, Jan-Philipp, Schumacher, Sabrina, Vonficht, Dominik, Solé-Boldo, Llorenç, Quick, Sabine, Steiger, Simon, Przybilla, Moritz J., Bauer, Katharina, Baumann, Anja, Hemmer, Stefan, Rehnitz, Christoph, Lückerath, Christian, Sachpekidis, Christos, Mechtersheimer, Gunhild, Haberkorn, Uwe, Dimitrakopoulou-Strauss, Antonia, Reichert, Philipp, Barlogie, Bart, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Hillengass, Jens, Rasche, Leo, Haas, Simon F., van Rhee, Frits, Rippe, Karsten, Raab, Marc S., Sauer, Sandra, Weinhold, Niels
Publicado 2023