Targeting Cellular Trafficking of Fibroblast Growth Factor Receptors as a Strategy for Selective Cancer Treatment

por Porębska, Natalia, Latko, Marta, Kucińska, Marika, Zakrzewska, Małgorzata, Otlewski, Jacek, Opaliński, Łukasz
Publicado 2018

Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins

por Latko, Marta, Czyrek, Aleksandra, Porębska, Natalia, Kucińska, Marika, Otlewski, Jacek, Zakrzewska, Małgorzata, Opaliński, Łukasz
Publicado 2019

Intrinsically Fluorescent Oligomeric Cytotoxic Conjugates Toxic for FGFR1-Overproducing Cancers

por Porębska, Natalia, Knapik, Agata, Poźniak, Marta, Krzyścik, Mateusz Adam, Zakrzewska, Małgorzata, Otlewski, Jacek, Opaliński, Łukasz
Publicado 2021

Differential regulation of fibroblast growth factor receptor 1 trafficking and function by extracellular galectins

por Kucińska, Marika, Porębska, Natalia, Lampart, Agata, Latko, Marta, Knapik, Agata, Zakrzewska, Małgorzata, Otlewski, Jacek, Opaliński, Łukasz
Publicado 2019

FGF1 Fusions with the Fc Fragment of IgG1 for the Assembly of GFPpolygons-Mediated Multivalent Complexes Recognizing FGFRs

por Poźniak, Marta, Zarzycka, Weronika, Porębska, Natalia, Knapik, Agata, Marczakiewicz-Perera, Paulina, Zakrzewska, Malgorzata, Otlewski, Jacek, Opaliński, Łukasz
Publicado 2021

The Significance of Cell Surface N-Glycosylation for Internalization and Potency of Cytotoxic Conjugates Targeting Receptor Tyrosine Kinases

por Poźniak, Marta, Żukowska, Dominika, Gędaj, Aleksandra, Krzyścik, Mateusz Adam, Porębska, Natalia, Zakrzewska, Małgorzata, Otlewski, Jacek, Opaliński, Łukasz
Publicado 2022

N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope

por Gregorczyk, Paulina, Porębska, Natalia, Żukowska, Dominika, Chorążewska, Aleksandra, Gędaj, Aleksandra, Malinowska, Agata, Otlewski, Jacek, Zakrzewska, Małgorzata, Opaliński, Łukasz
Publicado 2023

Receptor clustering by a precise set of extracellular galectins initiates FGFR signaling

por Zukowska, Dominika, Gedaj, Aleksandra, Porebska, Natalia, Pozniak, Marta, Krzyscik, Mateusz, Czyrek, Aleksandra, Krowarsch, Daniel, Zakrzewska, Malgorzata, Otlewski, Jacek, Opalinski, Lukasz
Publicado 2023

Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling

por Gedaj, Aleksandra, Zukowska, Dominika, Porebska, Natalia, Pozniak, Marta, Krzyscik, Mateusz, Czyrek, Aleksandra, Krowarsch, Daniel, Zakrzewska, Malgorzata, Otlewski, Jacek, Opalinski, Lukasz
Publicado 2023

Correction: Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling

por Gedaj, Aleksandra, Zukowska, Dominika, Porebska, Natalia, Pozniak, Marta, Krzyscik, Mateusz, Czyrek, Aleksandra, Krowarsch, Daniel, Zakrzewska, Malgorzata, Otlewski, Jacek, Opalinski, Lukasz
Publicado 2023

FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization

por Pozniak, Marta, Sokolowska‐Wedzina, Aleksandra, Jastrzebski, Kamil, Szymczyk, Jakub, Porebska, Natalia, Krzyscik, Mateusz Adam, Zakrzewska, Malgorzata, Miaczynska, Marta, Otlewski, Jacek, Opalinski, Lukasz
Publicado 2020

The cytotoxic conjugate of highly internalizing tetravalent antibody for targeting FGFR1-overproducing cancer cells

por Poźniak, Marta, Porębska, Natalia, Krzyścik, Mateusz Adam, Sokołowska-Wędzina, Aleksandra, Jastrzębski, Kamil, Sochacka, Martyna, Szymczyk, Jakub, Zakrzewska, Małgorzata, Otlewski, Jacek, Opaliński, Łukasz
Publicado 2021

Modular self-assembly system for development of oligomeric, highly internalizing and potent cytotoxic conjugates targeting fibroblast growth factor receptors

por Poźniak, Marta, Porębska, Natalia, Jastrzębski, Kamil, Krzyścik, Mateusz Adam, Kucińska, Marika, Zarzycka, Weronika, Barbach, Agnieszka, Zakrzewska, Małgorzata, Otlewski, Jacek, Miączyńska, Marta, Opaliński, Łukasz
Publicado 2021