Cranial irradiation at early postnatal age impairs stroke-induced neural stem/progenitor cell response in the adult brain

por Neumann, Susanne, Porritt, Michelle J., Osman, Ahmed M., Kuhn, H. Georg
Publicado 2020

PA28αβ overexpression enhances learning and memory of female mice without inducing 20S proteasome activity

por Adelöf, Julia, Andersson, My, Porritt, Michelle, Petersen, Anne, Zetterberg, Madeleine, Wiseman, John, Hernebring, Malin
Publicado 2018

Photothrombosis-Induced Infarction of the Mouse Cerebral Cortex Is Not Affected by the Nrf2-Activator Sulforaphane

por Porritt, Michelle J., Andersson, Helene C., Hou, Linda, Nilsson, Åsa, Pekna, Marcela, Pekny, Milos, Nilsson, Michael
Publicado 2012

Can Animal Models of Disease Reliably Inform Human Studies?

por van der Worp, H. Bart, Howells, David W., Sena, Emily S., Porritt, Michelle J., Rewell, Sarah, O'Collins, Victoria, Macleod, Malcolm R.
Publicado 2010

Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype

por Bjursell, Mikael, Porritt, Michelle J., Ericson, Elke, Taheri-Ghahfarokhi, Amir, Clausen, Maryam, Magnusson, Lisa, Admyre, Therese, Nitsch, Roberto, Mayr, Lorenz, Aasehaug, Leif, Seeliger, Frank, Maresca, Marcello, Bohlooly-Y, Mohammad, Wiseman, John
Publicado 2018

In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model

por Carreras, Alba, Pane, Luna Simona, Nitsch, Roberto, Madeyski-Bengtson, Katja, Porritt, Michelle, Akcakaya, Pinar, Taheri-Ghahfarokhi, Amir, Ericson, Elke, Bjursell, Mikael, Perez-Alcazar, Marta, Seeliger, Frank, Althage, Magnus, Knöll, Ralph, Hicks, Ryan, Mayr, Lorenz M., Perkins, Rosie, Lindén, Daniel, Borén, Jan, Bohlooly-Y, Mohammad, Maresca, Marcello
Publicado 2019

Universal toxin-based selection for precise genome engineering in human cells

por Li, Songyuan, Akrap, Nina, Cerboni, Silvia, Porritt, Michelle J., Wimberger, Sandra, Lundin, Anders, Möller, Carl, Firth, Mike, Gordon, Euan, Lazovic, Bojana, Sieńska, Aleksandra, Pane, Luna Simona, Coelho, Matthew A., Ciotta, Giovanni, Pellegrini, Giovanni, Sini, Marcella, Xu, Xiufeng, Mitra, Suman, Bohlooly-Y, Mohammad, Taylor, Benjamin J. M., Sienski, Grzegorz, Maresca, Marcello
Publicado 2021

Author Correction: Universal toxin-based selection for precise genome engineering in human cells

por Li, Songyuan, Akrap, Nina, Cerboni, Silvia, Porritt, Michelle J., Wimberger, Sandra, Lundin, Anders, Möller, Carl, Firth, Mike, Gordon, Euan, Lazovic, Bojana, Sieńska, Aleksandra, Pane, Luna Simona, Coelho, Matthew A., Ciotta, Giovanni, Pellegrini, Giovanni, Sini, Marcella, Xu, Xiufeng, Mitra, Suman, Bohlooly-Y, Mohammad, Taylor, Benjamin J. M., Sienski, Grzegorz, Maresca, Marcello
Publicado 2021

Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

por Lundin, Anders, Porritt, Michelle J., Jaiswal, Himjyot, Seeliger, Frank, Johansson, Camilla, Bidar, Abdel Wahad, Badertscher, Lukas, Wimberger, Sandra, Davies, Emma J., Hardaker, Elizabeth, Martins, Carla P., James, Emily, Admyre, Therese, Taheri-Ghahfarokhi, Amir, Bradley, Jenna, Schantz, Anna, Alaeimahabadi, Babak, Clausen, Maryam, Xu, Xiufeng, Mayr, Lorenz M., Nitsch, Roberto, Bohlooly-Y, Mohammad, Barry, Simon T., Maresca, Marcello
Publicado 2020

In vivo CRISPR editing with no detectable genome-wide off-target mutations

por Akcakaya, Pinar, Bobbin, Maggie L., Guo, Jimmy A., Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P., Fellows, Mick D., Porritt, Michelle J., Firth, Mike A., Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q., Nguyen, Nhu T., Nitsch, Roberto, Mayr, Lorenz M., Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J., Maresca, Marcello, Joung, J. Keith
Publicado 2018

IDOL regulates systemic energy balance through control of neuronal VLDLR expression

por Lee, Stephen D., Priest, Christina, Bjursell, Mikael, Gao, Jie, Arneson, Douglas V., Ahn, In Sook, Diamante, Graciel, van Veen, J. Edward, Massa, Megan G., Calkin, Anna C., Kim, Jason, Andersén, Harriet, Rajbhandari, Prashant, Porritt, Michelle, Carreras, Alba, Ahnmark, Andrea, Seeliger, Frank, Maxvall, Ingela, Eliasson, Pernilla, Althage, Magnus, Åkerblad, Peter, Lindén, Daniel, Cole, Tracy A., Lee, Richard, Boyd, Helen, Bohlooly-Y, Mohammad, Correa, Stephanie M., Yang, Xia, Tontonoz, Peter, Hong, Cynthia
Publicado 2019