Drosha Inclusions Are New Components of Dipeptide-Repeat Protein Aggregates in FTLD-TDP and ALS C9orf72 Expansion Cases

por Porta, Sílvia, Kwong, Linda K., Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2015

A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing

por Martí, Eulàlia, Pantano, Lorena, Bañez-Coronel, Mónica, Llorens, Franc, Miñones-Moyano, Elena, Porta, Sílvia, Sumoy, Lauro, Ferrer, Isidre, Estivill, Xavier
Publicado 2010

A Pathogenic Mechanism in Huntington's Disease Involves Small CAG-Repeated RNAs with Neurotoxic Activity

por Bañez-Coronel, Mónica, Porta, Silvia, Kagerbauer, Birgit, Mateu-Huertas, Elisabet, Pantano, Lorena, Ferrer, Isidre, Guzmán, Manuel, Estivill, Xavier, Martí, Eulàlia
Publicado 2012

Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage

por Kumar, Senthil T., Nazarov, Sergey, Porta, Sílvia, Maharjan, Niran, Cendrowska, Urszula, Kabani, Malek, Finamore, Francesco, Xu, Yan, Lee, Virginia M.-Y., Lashuel, Hilal A.
Publicado 2023

Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo

por Porta, Sílvia, Xu, Yan, Restrepo, Clark R., Kwong, Linda K., Zhang, Bin, Brown, Hannah J., Lee, Edward B., Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2018

Preclinical validation of a novel metastasis‐inhibiting Tie1 function‐blocking antibody

por Singhal, Mahak, Gengenbacher, Nicolas, La Porta, Silvia, Gehrs, Stephanie, Shi, Jingjing, Kamiyama, Miki, Bodenmiller, Diane M, Fischl, Anthony, Schieb, Benjamin, Besemfelder, Eva, Chintharlapalli, Sudhakar, Augustin, Hellmut G
Publicado 2020

Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

por Chung, Chia-Yu, Berson, Amit, Kennerdell, Jason R., Sartoris, Ashley, Unger, Travis, Porta, Sílvia, Kim, Hyung-Jun, Smith, Edwin R., Shilatifard, Ali, Van Deerlin, Vivianna, Lee, Virginia M.-Y., Chen-Plotkin, Alice, Bonini, Nancy M.
Publicado 2018

Author Correction: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

por Chung, Chia-Yu, Berson, Amit, Kennerdell, Jason R., Sartoris, Ashley, Unger, Travis, Porta, Sílvia, Kim, Hyung-Jun, Smith, Edwin R., Shilatifard, Ali, Van Deerlin, Vivianna, Lee, Virginia M. -Y., Chen-Plotkin, Alice, Bonini, Nancy M.
Publicado 2019

The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells

por Savant, Soniya, Porta, Silvia La, Budnik, Annika, Busch, Katrin, Hu, Junhao, Tisch, Nathalie, Korn, Claudia, Valls, Aida Freire, Benest, Andrew V., Terhardt, Dorothee, Qu, Xianghu, Adams, Ralf H., Baldwin, H. Scott, de Almodó var, Carmen Ruiz, Rodewald, Hans-Reimer, Augustin, Hellmut G.
Publicado 2015