An engineered genetic selection for ternary protein complexes inspired by a natural three-component hitchhiker mechanism

por Lee, Hyeon-Cheol, Portnoff, Alyse D., Rocco, Mark A., DeLisa, Matthew P.
Publicado 2014

An antidote approach to reduce risk and broaden utility of antibody-based therapeutics

por Portnoff, Alyse D., Gao, Cuihua, Borrok, M. Jack, Gao, Xizhe, Gao, Changshou, Rainey, G. Jonah
Publicado 2017

Influenza Hemagglutinin Nanoparticle Vaccine Elicits Broadly Neutralizing Antibodies against Structurally Distinct Domains of H3N2 HA

por Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Zhou, Haixia, Tian, Jing-Hui, Zhou, Bin, Shinde, Vivek, Glenn, Gregory M., Smith, Gale
Publicado 2020

Flexible RSV Prefusogenic Fusion Glycoprotein Exposes Multiple Neutralizing Epitopes that May Collectively Contribute to Protective Immunity

por Patel, Nita, Tian, Jing-Hui, Flores, Rhonda, Jacobson, Kelsey, Walker, Michelle, Portnoff, Alyse, Gueber-Xabier, Mimi, Massare, Michael J., Glenn, Greg, Ellingsworth, Larry, Smith, Gale
Publicado 2020

Targeted Fcγ Receptor (FcγR)-mediated Clearance by a Biparatopic Bispecific Antibody

por Kasturirangan, Srinath, Rainey, G. Jonah, Xu, Linda, Wang, Xinwei, Portnoff, Alyse, Chen, Tracy, Fazenbaker, Christine, Zhong, Helen, Bee, Jared, Zeng, Zhutian, Jenne, Craig, Wu, Herren, Gao, Changshou
Publicado 2017

NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge

por Guebre-Xabier, Mimi, Patel, Nita, Tian, Jing-Hui, Zhou, Bin, Maciejewski, Sonia, Lam, Kristal, Portnoff, Alyse D., Massare, Michael J., Frieman, Matthew B., Piedra, Pedro A., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale
Publicado 2020

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

por Bangaru, Sandhya, Ozorowski, Gabriel, Turner, Hannah L., Antanasijevic, Aleksandar, Huang, Deli, Wang, Xiaoning, Torres, Jonathan L., Diedrich, Jolene K., Tian, Jing-Hui, Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Yates, John R., Nemazee, David, Paulson, James C., Glenn, Greg, Smith, Gale, Ward, Andrew B.
Publicado 2020

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

por Bangaru, Sandhya, Ozorowski, Gabriel, Turner, Hannah L., Antanasijevic, Aleksandar, Huang, Deli, Wang, Xiaoning, Torres, Jonathan L., Diedrich, Jolene K., Tian, Jing-Hui, Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Yates, John R., Nemazee, David, Paulson, James C., Glenn, Greg, Smith, Gale, Ward, Andrew B.
Publicado 2020

Immunogenicity and protection of a variant nanoparticle vaccine that confers broad neutralization against SARS-CoV-2 variants

por Logue, James, Johnson, Robert M., Patel, Nita, Zhou, Bin, Maciejewski, Sonia, Foreman, Bryant, Zhou, Haixia, Portnoff, Alyse D., Tian, Jing-Hui, Rehman, Asma, McGrath, Marisa E., Haupt, Robert E., Weston, Stuart M., Baracco, Lauren, Hammond, Holly, Guebre-Xabier, Mimi, Dillen, Carly, Madhangi, M., Greene, Ann M., Massare, Michael J., Glenn, Greg M., Smith, Gale, Frieman, Matthew B.
Publicado 2023

Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination

por Alter, Galit, Gorman, Matthew, Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex, Atyeo, Caroline, Pullen, Krista, Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yuan, Dansu, Bowman, Kathryn, Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa, Logue, James, Frieman, Matthew, Montefiori, David, Schendel, Sharon, Saphire, Erica Ollmann, Lauffenburger, Douglas, Greene, Ann, Portnoff, Alyse, Massare, Michael, Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Mann, Colin, Amanat, Fatima, Krammer, Florian
Publicado 2021

SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice

por Tian, Jing-Hui, Patel, Nita, Haupt, Robert, Zhou, Haixia, Weston, Stuart, Hammond, Holly, Logue, James, Portnoff, Alyse D., Norton, James, Guebre-Xabier, Mimi, Zhou, Bin, Jacobson, Kelsey, Maciejewski, Sonia, Khatoon, Rafia, Wisniewska, Malgorzata, Moffitt, Will, Kluepfel-Stahl, Stefanie, Ekechukwu, Betty, Papin, James, Boddapati, Sarathi, Jason Wong, C., Piedra, Pedro A., Frieman, Matthew B., Massare, Michael J., Fries, Louis, Bengtsson, Karin Lövgren, Stertman, Linda, Ellingsworth, Larry, Glenn, Gregory, Smith, Gale
Publicado 2021

Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M(™) vaccination

por Gorman, Matthew J, Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex, Atyeo, Caroline, Pullen, Krista M., Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yaun, Dansu, Bowman, Kathryn, Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa E., Logue, James, Frieman, Matthew B., Montefiori, David, Mann, Colin, Schendel, Sharon, Amanat, Fatima, Krammer, Florian, Saphire, Erica Ollmann, Lauffenburger, Douglas, Greene, Ann M., Portnoff, Alyse D., Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Alter, Galit
Publicado 2021

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

por Gorman, Matthew J., Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex L., Atyeo, Caroline, Pullen, Krista M., Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yuan, Dansu, Bowman, Kathryn A., Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa E., Logue, James, Frieman, Matthew B., Montefiori, David, Mann, Colin, Schendel, Sharon, Amanat, Fatima, Krammer, Florian, Saphire, Erica Ollmann, Lauffenburger, Douglas A., Greene, Ann M., Portnoff, Alyse D., Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Alter, Galit
Publicado 2021