Combination immunotherapy with Interleukin-2 and CTLA-4 blockade decreases tumor growth and improves overall survival

por Broucek, Joseph R, Hughes, Tasha, Huelsmann, Erica J, Poshepny, Joseph L, Ruby, Carl E, Zloza, Andrew, Kaufman, Howard L
Publicado 2013

Combination immunotherapy with anti-CTLA-4 and interleukin-2 redirects regulatory T cells into tumor-draining lymph nodes and expands anti-tumor CD8+ T cells in the tumor microenvi...

por Broucek, Joseph, Hughes, Tasha, Huelsmann, Erica, Lusciks, Eugene, Hill , Graham, Zayas, Janet, Poshepny, Joseph, Ruby , Carl, Kohlhapp, Frederick, Zloza, Andrew, Kaufman, Howard
Publicado 2014

NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade

por Kohlhapp, Frederick J, Broucek, Joseph R, Hughes, Tasha, Huelsmann, Erica J, Lusciks, Jevgenijs, Zayas, Janet P, Dolubizno, Hubert, Fleetwood, Vidyaratna A, Grin, Alisa, Hill, Graham E, Poshepny, Joseph L, Nabatiyan, Arman, Ruby, Carl E, Snook, Joshua D, Rudra, Jai S, Schenkel, Jason M, Masopust, David, Zloza, Andrew, Kaufman, Howard L
Publicado 2015