Carpatamides A–C, Cytotoxic Arylamine Derivatives from a Marine-Derived Streptomyces sp.

por Fu, Peng, Johnson, Melissa, Chen, Hong, Posner, Bruce A., MacMillan, John B.
Publicado 2014

A highly-sensitive high throughput assay for dynamin's basal GTPase activity

por Mohanakrishnan, Aparna, Tran, Triet Vincent M., Kumar, Meera, Chen, Hong, Posner, Bruce A., Schmid, Sandra L.
Publicado 2017

GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors

por Thorne, Curtis A., Wichaidit, Chonlarat, Coster, Adam D., Posner, Bruce A., Wu, Lani F., Altschuler, Steven J.
Publicado 2014

Improving drug discovery with high-content phenotypic screens by systematic selection of reporter cell lines

por Kang, Jungseog, Hsu, Chien-Hsiang, Wu, Qi, Liu, Shanshan, Coster, Adam D., Posner, Bruce A., Altschuler, Steven J., Wu, Lani F.
Publicado 2015

Primate-Specific miR-576-3p Sets Host Defense Signaling Threshold

por Yarbrough, Melanie L., Zhang, Ke, Sakthivel, Ramanavelan, Forst, Christian V., Posner, Bruce A., Barber, Glen N., White, Michael A., Fontoura, Beatriz M.A.
Publicado 2014

Total synthesis of (+)-spiroindimicin A and congeners unveils their antiparasitic activity

por Zhang, Zhen, Ray, Sneha, Imlay, Leah, Callaghan, Lauren T., Niederstrasser, Hanspeter, Mallipeddi, Prema Latha, Posner, Bruce A., Wetzel, Dawn M., Phillips, Margaret A., Smith, Myles W.
Publicado 2021

Small molecule glucagon release inhibitors with activity in human islets

por Kalwat, Michael A., Rodrigues-dos-Santos, Karina, Binns, Derk D., Wei, Shuguang, Zhou, Anwu, Evans, Matthew R., Posner, Bruce A., Roth, Michael G., Cobb, Melanie H.
Publicado 2023

ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression

por Zhou, Huanyu, Morales, Maria Gabriela, Hashimoto, Hisayuki, Dickson, Matthew E., Song, Kunhua, Ye, Wenduo, Kim, Min S., Niederstrasser, Hanspeter, Wang, Zhaoning, Chen, Beibei, Posner, Bruce A., Bassel-Duby, Rhonda, Olson, Eric N.
Publicado 2017

The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions

por Jung, Hunmin, Takeshima, Tomomi, Nakagawa, Tsutomu, MacMillan, Karen S., Wynn, R. Max, Wang, Hanzhi, Sakiyama, Haruhiko, Wei, Shuguang, Li, Yang, Bruick, Richard K., Posner, Bruce A., De Brabander, Jef K., Uyeda, Kosaku
Publicado 2020

SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

por Tagal, Vural, Wei, Shuguang, Zhang, Wei, Brekken, Rolf A., Posner, Bruce A., Peyton, Michael, Girard, Luc, Hwang, TaeHyun, Wheeler, David A., Minna, John D., White, Michael A., Gazdar, Adi F., Roth, Michael G.
Publicado 2017

Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics

por Layeghi-Ghalehsoukhteh, Somayeh, Pal Choudhuri, Shreoshi, Ocal, Ozhan, Zolghadri, Yalda, Pashkov, Victor, Niederstrasser, Hanspeter, Posner, Bruce A., Kantheti, Havish S., Azevedo-Pouly, Ana C., Huang, Huocong, Girard, Luc, MacDonald, Raymond J., Brekken, Rolf A., Wilkie, Thomas M.
Publicado 2020

Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells

por Ramirez, Michael, Rajaram, Satwik, Steininger, Robert J., Osipchuk, Daria, Roth, Maike A., Morinishi, Leanna S., Evans, Louise, Ji, Weiyue, Hsu, Chien-Hsiang, Thurley, Kevin, Wei, Shuguang, Zhou, Anwu, Koduru, Prasad R., Posner, Bruce A., Wu, Lani F., Altschuler, Steven J.
Publicado 2016

Discovery of Tumor-Specific Irreversible Inhibitors of Stearoyl CoA Desaturase

por Theodoropoulos, Panayotis C., Gonzales, Stephen S., Winterton, Sarah E., Rodriguez-Navas, Carlos, McKnight, John S., Morlock, Lorraine K., Hanson, Jordan M., Cross, Bethany, Owen, Amy E., Duan, Yingli, Moreno, Jose R., Lemoff, Andrew, Mirzaei, Hamid, Posner, Bruce A., Williams, Noelle S., Ready, Joseph M., Nijhawan, Deepak
Publicado 2016

Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan

por Wang, Chensu, Niederstrasser, Hanspeter, Douglas, Peter M., Lin, Rueyling, Jaramillo, Juan, Li, Yang, Oswald, Nathaniel W., Zhou, Anwu, McMillan, Elizabeth A., Mendiratta, Saurabh, Wang, Zhaohui, Zhao, Tian, Lin, Zhiqaing, Luo, Min, Huang, Gang, Brekken, Rolf A., Posner, Bruce A., MacMillan, John B., Gao, Jinming, White, Michael A.
Publicado 2017

Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan

por Wang, Chensu, Niederstrasser, Hanspeter, Douglas, Peter M., Lin, Rueyling, Jaramillo, Juan, Li, Yang, Oswald, Nathaniel W., Zhou, Anwu, McMillan, Elizabeth A., Mendiratta, Saurabh, Wang, Zhaohui, Zhao, Tian, Lin, Zhiqaing, Luo, Min, Huang, Gang, Brekken, Rolf A., Posner, Bruce A., MacMillan, John B., Gao, Jinming, White, Michael A.
Publicado 2018

Targeting ESR1 mutation–induced transcriptional addiction in breast cancer with BET inhibition

por Udden, Sm N., Wang, Qian, Kumar, Sunil, Malladi, Venkat S., Wu, Shwu-Yuan, Wei, Shuguang, Posner, Bruce A., Geboers, Sophie, Williams, Noelle S., Liu, Yulun, Sharma, Jayesh K., Mani, Ram S., Malladi, Srinivas, Parra, Karla, Hofstad, Mia, Raj, Ganesh V., Larios, Jose M., Jagsi, Reshma, Wicha, Max S., Park, Ben Ho, Gupta, Gaorav P., Chinnaiyan, Arul M., Chiang, Cheng-Ming, Alluri, Prasanna G.
Publicado 2022