Effect of intranasally administered insulin on cerebral blood flow and perfusion; a randomized experiment in young and older adults

por Akintola, Abimbola A., van Opstal, Anna M., Westendorp, Rudi G., Postmus, Iris, van der Grond, Jeroen, van Heemst, Diana
Publicado 2017

External validity of randomized controlled trials in older adults, a systematic review

por van Deudekom, Floor J., Postmus, Iris, van der Ham, Danielle J., Pothof, Alexander B., Broekhuizen, Karen, Blauw, Gerard J., Mooijaart, Simon P.
Publicado 2017

Systematic Testing of Literature Reported Genetic Variation Associated with Coronary Restenosis: Results of the GENDER Study

por Verschuren, Jeffrey J. W., Trompet, Stella, Postmus, Iris, Sampietro, M. Lourdes, Heijmans, Bastiaan T., Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Jukema, J. Wouter
Publicado 2012

A potential harmful effect of dexamethasone in non-severe COVID-19: results from the COPPER-pilot study

por Kocks, Janwillem, Kerkhof, Marjan, Scherpenisse, Jan, van de Maat, Aimée, van Geer-Postmus, Iris, le Rütte, Thomas, Schaart, Jan, Gans, Reinold O.B., Kerstjens, Huib A.M.
Publicado 2022

Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes

por van der Kroef, Sabrina, Noordam, Raymond, Deelen, Joris, Akintola, Abimbola A., Jansen, Steffy W. M., Postmus, Iris, Wijsman, Carolien A., Beekman, Marian, Mooijaart, Simon P., Slagboom, P. Eline, van Heemst, Diana
Publicado 2016

Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses

por Trompet, Stella, de Craen, Anton JM, Postmus, Iris, Ford, Ian, Sattar, Naveed, Caslake, Muriel, Stott, David J, Buckley, Brendan M, Sacks, Frank, Devlin, James J, Slagboom, P Eline, Westendorp, Rudi GJ, Jukema, J Wouter
Publicado 2011

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

por Trompet, Stella, Postmus, Iris, Warren, Helen R., Noordam, Raymond, Smit, Roelof A. J., Theusch, Elizabeth, Li, Xiaohui, Arsenault, Benoit, Chasman, Daniel I., Hitman, Graham A., Munroe, Patricia B., Rotter, Jerome I., Psaty, Bruce M., Caulfield, Mark J., Krauss, Ron M., Cupples, Adrienne L., Jukema, Wouter J.
Publicado 2022

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

por Deelen, Joris, Beekman, Marian, Codd, Veryan, Trompet, Stella, Broer, Linda, Hägg, Sara, Fischer, Krista, Thijssen, Peter E, Suchiman, H Eka D, Postmus, Iris, Uitterlinden, André G, Hofman, Albert, de Craen, Anton J M, Metspalu, Andres, Pedersen, Nancy L, van Duijn, Cornelia M, Wouter Jukema, J, Houwing-Duistermaat, Jeanine J, Samani, Nilesh J, Eline Slagboom, P
Publicado 2014

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

por Smit, Roelof AJ, Trompet, Stella, Leong, Aaron, Goodarzi, Mark O, Postmus, Iris, Warren, Helen, Theusch, Elizabeth, Barnes, Michael R, Arsenault, Benoit J, Li, Xiaohui, Feng, QiPing, Chasman, Daniel I, Cupples, L Adrienne, Hitman, Graham A, Krauss, Ronald M, Psaty, Bruce M, Rotter, Jerome I, le Cessie, Saskia, Stein, C Michael, Jukema, J Wouter
Publicado 2019

Design and rationale of a routine clinical care pathway and prospective cohort study in older patients needing intensive treatment

por van Holstein, Yara, van Deudekom, Floor J., Trompet, Stella, Postmus, Iris, Uit den Boogaard, Anna, van der Elst, Marjan J. T., de Glas, Nienke A., van Heemst, Diana, Labots, Geert, Altena, Mariëtte, Slingerland, Marije, Liefers, Gerrit Jan, van den Bos, Frederiek, van der Bol, Jessica M., Blauw, Gerard J., Portielje, Johanneke E. A., Mooijaart, Simon P.
Publicado 2021

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)

por Deshmukh, Harshal A., Colhoun, Helen M., Johnson, Toby, McKeigue, Paul M., Betteridge, D. John, Durrington, Paul N., Fuller, John H., Livingstone, Shona, Charlton-Menys, Valentine, Neil, Andrew, Poulter, Neil, Sever, Peter, Shields, Denis C., Stanton, Alice V., Chatterjee, Aurobindo, Hyde, Craig, Calle, Roberto A., DeMicco, David A., Trompet, Stella, Postmus, Iris, Ford, Ian, Jukema, J. Wouter, Caulfield, Mark, Hitman, Graham A.
Publicado 2012

Factors associated with health status and exacerbations in COPD maintenance therapy with dry powder inhalers

por W. H. Kocks, Janwillem, Wouters, Hans, Bosnic-Anticevich, Sinthia, van Cooten, Joyce, Correia de Sousa, Jaime, Cvetkovski, Biljana, Dekhuijzen, Richard, Dijk, Lars, Dvortsin, Evgeni, Garcia Pardo, Marina, Gardev, Asparuh, Gawlik, Radosław, van Geer - Postmus, Iris, van der Ham, Iris, Harbers, Marten, de la Hoz, Alberto, Janse, Ymke, Kerkhof, Marjan, Lavorini, Federico, Maricoto, Tiago, Meijer, Jiska, Metz, Boyd, Price, David, Roman-Rodriguez, Miguel, Schuttel, Kirsten, Stoker, Nilouq, Tsiligianni, Ioanna, Usmani, Omar, Leving, Marika T.
Publicado 2022

Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers

por Taylor, Amy E., Morris, Richard W., Fluharty, Meg E., Bjorngaard, Johan H., Åsvold, Bjørn Olav, Gabrielsen, Maiken E., Campbell, Archie, Marioni, Riccardo, Kumari, Meena, Hällfors, Jenni, Männistö, Satu, Marques-Vidal, Pedro, Kaakinen, Marika, Cavadino, Alana, Postmus, Iris, Husemoen, Lise Lotte N., Skaaby, Tea, Ahluwalia, Tarunveer S., Treur, Jorien L., Willemsen, Gonneke, Dale, Caroline, Wannamethee, S. Goya, Lahti, Jari, Palotie, Aarno, Räikkönen, Katri, Kisialiou, Aliaksei, McConnachie, Alex, Padmanabhan, Sandosh, Wong, Andrew, Dalgård, Christine, Paternoster, Lavinia, Ben-Shlomo, Yoav, Tyrrell, Jessica, Horwood, John, Fergusson, David M., Kennedy, Martin A., Frayling, Tim, Nohr, Ellen A., Christiansen, Lene, Ohm Kyvik, Kirsten, Kuh, Diana, Watt, Graham, Eriksson, Johan, Whincup, Peter H., Vink, Jacqueline M., Boomsma, Dorret I., Davey Smith, George, Lawlor, Debbie, Linneberg, Allan, Ford, Ian, Jukema, J. Wouter, Power, Christine, Hyppönen, Elina, Jarvelin, Marjo-Riitta, Preisig, Martin, Borodulin, Katja, Kaprio, Jaakko, Kivimaki, Mika, Smith, Blair H., Hayward, Caroline, Romundstad, Pål R., Sørensen, Thorkild I. A., Munafò, Marcus R., Sattar, Naveed
Publicado 2014

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

por Morris, Richard W, Taylor, Amy E, Fluharty, Meg E, Bjørngaard, Johan H, Åsvold, Bjørn Olav, Elvestad Gabrielsen, Maiken, Campbell, Archie, Marioni, Riccardo, Kumari, Meena, Korhonen, Tellervo, Männistö, Satu, Marques-Vidal, Pedro, Kaakinen, Marika, Cavadino, Alana, Postmus, Iris, Husemoen, Lise Lotte N, Skaaby, Tea, Ahluwalia, Tarun Veer Singh, Treur, Jorien L, Willemsen, Gonneke, Dale, Caroline, Wannamethee, S Goya, Lahti, Jari, Palotie, Aarno, Räikkönen, Katri, McConnachie, Alex, Padmanabhan, Sandosh, Wong, Andrew, Dalgård, Christine, Paternoster, Lavinia, Ben-Shlomo, Yoav, Tyrrell, Jessica, Horwood, John, Fergusson, David M, Kennedy, Martin A, Nohr, Ellen A, Christiansen, Lene, Kyvik, Kirsten Ohm, Kuh, Diana, Watt, Graham, Eriksson, Johan G, Whincup, Peter H, Vink, Jacqueline M, Boomsma, Dorret I, Davey Smith, George, Lawlor, Debbie, Linneberg, Allan, Ford, Ian, Jukema, J Wouter, Power, Chris, Hyppönen, Elina, Jarvelin, Marjo-Riitta, Preisig, Martin, Borodulin, Katja, Kaprio, Jaakko, Kivimaki, Mika, Smith, Blair H, Hayward, Caroline, Romundstad, Pål R, Sørensen, Thorkild I A, Munafò, Marcus R, Sattar, Naveed
Publicado 2015

Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

por van Leeuwen, Elisabeth M., Karssen, Lennart C., Deelen, Joris, Isaacs, Aaron, Medina-Gomez, Carolina, Mbarek, Hamdi, Kanterakis, Alexandros, Trompet, Stella, Postmus, Iris, Verweij, Niek, van Enckevort, David J., Huffman, Jennifer E., White, Charles C., Feitosa, Mary F., Bartz, Traci M., Manichaikul, Ani, Joshi, Peter K., Peloso, Gina M., Deelen, Patrick, van Dijk, Freerk, Willemsen, Gonneke, de Geus, Eco J., Milaneschi, Yuri, Penninx, Brenda W.J.H., Francioli, Laurent C., Menelaou, Androniki, Pulit, Sara L., Rivadeneira, Fernando, Hofman, Albert, Oostra, Ben A., Franco, Oscar H., Leach, Irene Mateo, Beekman, Marian, de Craen, Anton J.M., Uh, Hae-Won, Trochet, Holly, Hocking, Lynne J., Porteous, David J., Sattar, Naveed, Packard, Chris J., Buckley, Brendan M., Brody, Jennifer A., Bis, Joshua C., Rotter, Jerome I., Mychaleckyj, Josyf C., Campbell, Harry, Duan, Qing, Lange, Leslie A., Wilson, James F., Hayward, Caroline, Polasek, Ozren, Vitart, Veronique, Rudan, Igor, Wright, Alan F., Rich, Stephen S., Psaty, Bruce M., Borecki, Ingrid B., Kearney, Patricia M., Stott, David J., Adrienne Cupples, L., Jukema, J. Wouter, van der Harst, Pim, Sijbrands, Eric J., Hottenga, Jouke-Jan, Uitterlinden, Andre G., Swertz, Morris A., van Ommen, Gert-Jan B., de Bakker, Paul I.W., Eline Slagboom, P., Boomsma, Dorret I., Wijmenga, Cisca, van Duijn, Cornelia M.
Publicado 2015

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

por Deelen, Joris, Beekman, Marian, Uh, Hae-Won, Broer, Linda, Ayers, Kristin L., Tan, Qihua, Kamatani, Yoichiro, Bennet, Anna M., Tamm, Riin, Trompet, Stella, Guðbjartsson, Daníel F., Flachsbart, Friederike, Rose, Giuseppina, Viktorin, Alexander, Fischer, Krista, Nygaard, Marianne, Cordell, Heather J., Crocco, Paolina, van den Akker, Erik B., Böhringer, Stefan, Helmer, Quinta, Nelson, Christopher P., Saunders, Gary I., Alver, Maris, Andersen-Ranberg, Karen, Breen, Marie E., van der Breggen, Ruud, Caliebe, Amke, Capri, Miriam, Cevenini, Elisa, Collerton, Joanna C., Dato, Serena, Davies, Karen, Ford, Ian, Gampe, Jutta, Garagnani, Paolo, de Geus, Eco J.C., Harrow, Jennifer, van Heemst, Diana, Heijmans, Bastiaan T., Heinsen, Femke-Anouska, Hottenga, Jouke-Jan, Hofman, Albert, Jeune, Bernard, Jonsson, Palmi V., Lathrop, Mark, Lechner, Doris, Martin-Ruiz, Carmen, Mcnerlan, Susan E., Mihailov, Evelin, Montesanto, Alberto, Mooijaart, Simon P., Murphy, Anne, Nohr, Ellen A., Paternoster, Lavinia, Postmus, Iris, Rivadeneira, Fernando, Ross, Owen A., Salvioli, Stefano, Sattar, Naveed, Schreiber, Stefan, Stefánsson, Hreinn, Stott, David J., Tiemeier, Henning, Uitterlinden, André G., Westendorp, Rudi G.J., Willemsen, Gonneke, Samani, Nilesh J., Galan, Pilar, Sørensen, Thorkild I.A., Boomsma, Dorret I., Jukema, J. Wouter, Rea, Irene Maeve, Passarino, Giuseppe, de Craen, Anton J.M., Christensen, Kaare, Nebel, Almut, Stefánsson, Kári, Metspalu, Andres, Magnusson, Patrik, Blanché, Hélène, Christiansen, Lene, Kirkwood, Thomas B.L., van Duijn, Cornelia M., Franceschi, Claudio, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline
Publicado 2014

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

por Postmus, Iris, Trompet, Stella, Deshmukh, Harshal A., Barnes, Michael R., Li, Xiaohui, Warren, Helen R., Chasman, Daniel I., Zhou, Kaixin, Arsenault, Benoit J., Donnelly, Louise A., Wiggins, Kerri L., Avery, Christy L., Griffin, Paula, Feng, QiPing, Taylor, Kent D., Li, Guo, Evans, Daniel S., Smith, Albert V., de Keyser, Catherine E., Johnson, Andrew D., de Craen, Anton J. M., Stott, David J., Buckley, Brendan M., Ford, Ian, Westendorp, Rudi G. J., Eline Slagboom, P., Sattar, Naveed, Munroe, Patricia B., Sever, Peter, Poulter, Neil, Stanton, Alice, Shields, Denis C., O’Brien, Eoin, Shaw-Hawkins, Sue, Ida Chen, Y.-D., Nickerson, Deborah A., Smith, Joshua D., Pierre Dubé, Marie, Matthijs Boekholdt, S., Kees Hovingh, G., Kastelein, John J. P., McKeigue, Paul M., Betteridge, John, Neil, Andrew, Durrington, Paul N., Doney, Alex, Carr, Fiona, Morris, Andrew, McCarthy, Mark I., Groop, Leif, Ahlqvist, Emma, Bis, Joshua C., Rice, Kenneth, Smith, Nicholas L., Lumley, Thomas, Whitsel, Eric A., Stürmer, Til, Boerwinkle, Eric, Ngwa, Julius S., O’Donnell, Christopher J., Vasan, Ramachandran S., Wei, Wei-Qi, Wilke, Russell A., Liu, Ching-Ti, Sun, Fangui, Guo, Xiuqing, Heckbert, Susan R, Post, Wendy, Sotoodehnia, Nona, Arnold, Alice M., Stafford, Jeanette M., Ding, Jingzhong, Herrington, David M., Kritchevsky, Stephen B., Eiriksdottir, Gudny, Launer, Leonore J., Harris, Tamara B., Chu, Audrey Y., Giulianini, Franco, MacFadyen, Jean G., Barratt, Bryan J., Nyberg, Fredrik, Stricker, Bruno H., Uitterlinden, André G., Hofman, Albert, Rivadeneira, Fernando, Emilsson, Valur, Franco, Oscar H., Ridker, Paul M., Gudnason, Vilmundur, Liu, Yongmei, Denny, Joshua C., Ballantyne, Christie M., Rotter, Jerome I., Adrienne Cupples, L., Psaty, Bruce M., Palmer, Colin N. A., Tardif, Jean-Claude, Colhoun, Helen M., Hitman, Graham, Krauss, Ronald M., Wouter Jukema, J, Caulfield, Mark J.
Publicado 2014

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

por Teumer, Alexander, Chaker, Layal, Groeneweg, Stefan, Li, Yong, Di Munno, Celia, Barbieri, Caterina, Schultheiss, Ulla T., Traglia, Michela, Ahluwalia, Tarunveer S., Akiyama, Masato, Appel, Emil Vincent R., Arking, Dan E., Arnold, Alice, Astrup, Arne, Beekman, Marian, Beilby, John P., Bekaert, Sofie, Boerwinkle, Eric, Brown, Suzanne J., De Buyzere, Marc, Campbell, Purdey J., Ceresini, Graziano, Cerqueira, Charlotte, Cucca, Francesco, Deary, Ian J., Deelen, Joris, Eckardt, Kai-Uwe, Ekici, Arif B., Eriksson, Johan G., Ferrrucci, Luigi, Fiers, Tom, Fiorillo, Edoardo, Ford, Ian, Fox, Caroline S., Fuchsberger, Christian, Galesloot, Tessel E., Gieger, Christian, Gögele, Martin, De Grandi, Alessandro, Grarup, Niels, Greiser, Karin Halina, Haljas, Kadri, Hansen, Torben, Harris, Sarah E., van Heemst, Diana, den Heijer, Martin, Hicks, Andrew A., den Hollander, Wouter, Homuth, Georg, Hui, Jennie, Ikram, M. Arfan, Ittermann, Till, Jensen, Richard A., Jing, Jiaojiao, Jukema, J. Wouter, Kajantie, Eero, Kamatani, Yoichiro, Kasbohm, Elisa, Kaufman, Jean-Marc, Kiemeney, Lambertus A., Kloppenburg, Margreet, Kronenberg, Florian, Kubo, Michiaki, Lahti, Jari, Lapauw, Bruno, Li, Shuo, Liewald, David C. M., Lim, Ee Mun, Linneberg, Allan, Marina, Michela, Mascalzoni, Deborah, Matsuda, Koichi, Medenwald, Daniel, Meisinger, Christa, Meulenbelt, Ingrid, De Meyer, Tim, Meyer zu Schwabedissen, Henriette E., Mikolajczyk, Rafael, Moed, Matthijs, Netea-Maier, Romana T., Nolte, Ilja M., Okada, Yukinori, Pala, Mauro, Pattaro, Cristian, Pedersen, Oluf, Petersmann, Astrid, Porcu, Eleonora, Postmus, Iris, Pramstaller, Peter P., Psaty, Bruce M., Ramos, Yolande F. M., Rawal, Rajesh, Redmond, Paul, Richards, J. Brent, Rietzschel, Ernst R., Rivadeneira, Fernando, Roef, Greet, Rotter, Jerome I., Sala, Cinzia F., Schlessinger, David, Selvin, Elizabeth, Slagboom, P. Eline, Soranzo, Nicole, Sørensen, Thorkild I. A., Spector, Timothy D., Starr, John M., Stott, David J., Taes, Youri, Taliun, Daniel, Tanaka, Toshiko, Thuesen, Betina, Tiller, Daniel, Toniolo, Daniela, Uitterlinden, Andre G., Visser, W. Edward, Walsh, John P., Wilson, Scott G., Wolffenbuttel, Bruce H. R., Yang, Qiong, Zheng, Hou-Feng, Cappola, Anne, Peeters, Robin P., Naitza, Silvia, Völzke, Henry, Sanna, Serena, Köttgen, Anna, Visser, Theo J., Medici, Marco
Publicado 2018