Class III β-tubulin expression and in vitro resistance to microtubule targeting agents

por Stengel, C, Newman, S P, Leese, M P, Potter, B V L, Reed, M J, Purohit, A
Publicado 2010

Inhibition of Steroid Sulfatase Activity in Endometriotic Implants by STX64 (667Coumate): A Potential New Therapy

por Fusi, L., Purohit, A., Brosens, J., Woo, L. W. L., Potter, B. V. L., Reed, M. J.
Publicado 2008

In vivo inhibition of angiogenesis by sulphamoylated derivatives of 2-methoxyoestradiol

por Chander, S K, Foster, P A, Leese, M P, Newman, S P, Potter, B V L, Purohit, A, Reed, M J
Publicado 2007

2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer

por Tagg, S L C, Foster, P A, Leese, M P, Potter, B V L, Reed, M J, Purohit, A, Newman, S P
Publicado 2008

A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate

por Falasca, M, Chiozzotto, D, Godage, H Y, Mazzoletti, M, Riley, A M, Previdi, S, Potter, B V L, Broggini, M, Maffucci, T
Publicado 2010

Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats

por Ireson, C R, Chander, S K, Purohit, A, Parish, D C, Woo, L W L, Potter, B V L, Reed, M J
Publicado 2004

Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents

por Ireson, C R, Chander, S K, Purohit, A, Perera, S, Newman, S P, Parish, D, Leese, M P, Smith, A C, Potter, B V L, Reed, M J
Publicado 2004

The in vivo properties of STX243: a potent angiogenesis inhibitor in breast cancer

por Parsons, M F C, Foster, P A, Chander, S K, Jhalli, R, Newman, S P, Leese, M P, Potter, B V L, Purohit, A, Reed, M J
Publicado 2008

BCRP expression does not result in resistance to STX140 in vivo, despite the increased expression of BCRP in A2780 cells in vitro after long-term STX140 exposure

por Day, J M, Foster, P A, Tutill, H J, Newman, S P, Ho, Y T, Leese, M P, Potter, B V L, Reed, M J, Purohit, A
Publicado 2009

The therapeutic potential of a series of orally bioavailable anti-angiogenic microtubule disruptors as therapy for hormone-independent prostate and breast cancers

por Newman, S P, Foster, P A, Ho, Y T, Day, J M, Raobaikady, B, Kasprzyk, P G, Leese, M P, Potter, B V L, Reed, M J, Purohit, A
Publicado 2007

In vivo and in vitro properties of STX2484: a novel non-steroidal anti-cancer compound active in taxane-resistant breast cancer

por Stengel, C, Newman, S P, Day, J M, Chander, S K, Jourdan, F L, Leese, M P, Ferrandis, E, Regis-Lydi, S, Potter, B V L, Reed, M J, Purohit, A, Foster, P A
Publicado 2014