Rationale for Targeting Deregulated Metabolic Pathways as a Therapeutic Strategy in Acute Myeloid Leukemia

por Chapuis, Nicolas, Poulain, Laury, Birsen, Rudy, Tamburini, Jerome, Bouscary, Didier
Publicado 2019

AMP-Activated Protein Kinase Contributes to Apoptosis Induced by the Bcl-2 Inhibitor Venetoclax in Acute Myeloid Leukemia

por Legrand, Noémie, Pradier, Amandine, Poulain, Laury, Mouche, Sarah, Birsen, Rudy, Larrue, Clément, Simonetta, Federico, Tamburini, Jerome
Publicado 2021

Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia

por Larrue, Clement, Mouche, Sarah, Lin, Shan, Simonetta, Federico, Scheidegger, Nastassja K., Poulain, Laury, Birsen, Rudy, Sarry, Jean-Emmanuel, Stegmaier, Kimberly, Tamburini, Jerome
Publicado 2023

Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells

por Varin, Jennifer, Poulain, Laury, Hivelin, Mikael, Nusbaum, Patrick, Hubas, Arnaud, Laurendeau, Ingrid, Lantieri, Laurent, Wolkenstein, Pierre, Vidaud, Michel, Pasmant, Eric, Chapuis, Nicolas, Parfait, Béatrice
Publicado 2016

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

por Green, Alexa S., Maciel, Thiago T., Hospital, Marie-Anne, Yin, Chae, Mazed, Fetta, Townsend, Elizabeth C., Pilorge, Sylvain, Lambert, Mireille, Paubelle, Etienne, Jacquel, Arnaud, Zylbersztejn, Florence, Decroocq, Justine, Poulain, Laury, Sujobert, Pierre, Jacque, Nathalie, Adam, Kevin, So, Jason C. C., Kosmider, Olivier, Auberger, Patrick, Hermine, Olivier, Weinstock, David M., Lacombe, Catherine, Mayeux, Patrick, Vanasse, Gary J., Leung, Anskar Y., Moura, Ivan C., Bouscary, Didier, Tamburini, Jerome
Publicado 2015

RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia

por Decroocq, Justine, Birsen, Rudy, Montersino, Camille, Chaskar, Prasad, Mano, Jordi, Poulain, Laury, Friedrich, Chloe, Alary, Anne-Sophie, Guermouche, Helene, Sahal, Ambrine, Fouquet, Guillemette, Gotanègre, Mathilde, Simonetta, Federico, Mouche, Sarah, Gestraud, Pierre, Lescure, Auriane, Del Nery, Elaine, Bosc, Claudie, Grenier, Adrien, Mazed, Fetta, Mondesir, Johanna, Chapuis, Nicolas, Ho, Liza, Boughalem, Aicha, Lelorc’h, Marc, Gobeaux, Camille, Fontenay, Michaela, Recher, Christian, Vey, Norbert, Guillé, Arnaud, Birnbaum, Daniel, Hermine, Olivier, Radford-Weiss, Isabelle, Tsantoulis, Petros, Collette, Yves, Castellano, Rémy, Sarry, Jean-Emmanuel, Pasmant, Eric, Bouscary, Didier, Kosmider, Olivier, Tamburini, Jerome
Publicado 2022