Combined in vitro/in vivo genome-wide CRISPR screens in triple negative breast cancer identify cancer stemness regulators in paclitaxel resistance

por Yan, Gang, Dai, Meiou, Poulet, Sophie, Wang, Ni, Boudreault, Julien, Daliah, Girija, Ali, Suhad, Lebrun, Jean-Jacques
Publicado 2023

TGFβ/cyclin D1/Smad-mediated inhibition of BMP4 promotes breast cancer stem cell self-renewal activity

por Yan, Gang, Dai, Meiou, Zhang, Chenjing, Poulet, Sophie, Moamer, Alaa, Wang, Ni, Boudreault, Julien, Ali, Suhad, Lebrun, Jean-Jacques
Publicado 2021

In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy

por Dai, Meiou, Yan, Gang, Wang, Ni, Daliah, Girija, Edick, Ashlin M., Poulet, Sophie, Boudreault, Julien, Ali, Suhad, Burgos, Sergio A., Lebrun, Jean-Jacques
Publicado 2021