Na(V)1.5 knockout in iPSCs: a novel approach to study Na(V)1.5 variants in a human cardiomyocyte environment

por Pierre, Marion, Djemai, Mohammed, Poulin, Hugo, Chahine, Mohamed
Publicado 2021

iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities

por Poulin, Hugo, Mercier, Aurélie, Djemai, Mohammed, Pouliot, Valérie, Deschenes, Isabelle, Boutjdir, Mohamed, Puymirat, Jack, Chahine, Mohamed
Publicado 2021

De novo Y1460C missense variant in Na(V)1.1 impedes the pore region and results in epileptic encephalopathy

por Plumereau, Quentin, Ebdalla, Aya, Poulin, Hugo, Appendino, Juan Pablo, Scantlebury, Morris H., Au, Ping Yee Billie, Chahine, Mohamed
Publicado 2022

Substitutions of the S4DIV R2 residue (R1451) in Na(V)1.4 lead to complex forms of paramyotonia congenita and periodic paralyses

por Poulin, Hugo, Gosselin-Badaroudine, Pascal, Vicart, Savine, Habbout, Karima, Sternberg, Damien, Giuliano, Serena, Fontaine, Bertrand, Bendahhou, Saïd, Nicole, Sophie, Chahine, Mohamed
Publicado 2018