Computational analysis of the tryptophan cation radical energetics in peroxidase Compound I

por Poulos, Thomas L., Kim, Jenny S., Murarka, Vidhi C.
Publicado 2022

Structural Insights on the Conversion of Cytochrome P450 to P420

por Gable, Jessica A., Tripathi, Sarvind, Poulos, Thomas L
Publicado 2022

Elucidating nitric oxide synthase domain interactions by molecular dynamics

por Hollingsworth, Scott A., Holden, Jeffrey K., Li, Huiying, Poulos, Thomas L.
Publicado 2015

Communication between the Zinc and Tetrahydrobiopterin Binding Sites in Nitric Oxide Synthase

por Chreifi, Georges, Li, Huiying, McInnes, Craig R., Gibson, Colin L., Suckling, Colin J., Poulos, Thomas L.
Publicado 2014

Structural analysis of P450 AmphL from Streptomyces nodosus provides insights into substrate selectivity of polyene macrolide antibiotic biosynthetic P450s

por Amaya, Jose A., Lamb, David C., Kelly, Steven L., Caffrey, Patrick, Murarka, Vidhi C., Poulos, Thomas L.
Publicado 2022

Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

por Cinelli, Maris A., Li, Huiying, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Publicado 2014

Nitric Oxide Synthase Inhibitors That Interact with Both Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity

por Kang, Soosung, Tang, Wei, Li, Huiying, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Publicado 2014

Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase

por Mukherjee, Paramita, Li, Huiying, Sevrioukova, Irina, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Publicado 2014

Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1

por Lewis-Ballester, Ariel, Pham, Khoa N., Batabyal, Dipanwita, Karkashon, Shay, Bonanno, Jeffrey B., Poulos, Thomas L., Yeh, Syun-Ru
Publicado 2017

Crystal Structure of Cindoxin, the P450cin Redox Partner

por Madrona, Yarrow, Hollingsworth, Scott A., Tripathi, Sarvind, Fields, James B., Rwigema, Jean-Christophe N., Tobias, Douglas J., Poulos, Thomas L.
Publicado 2014

Pulsed Electron Paramagnetic Resonance Study of Domain Docking in Neuronal Nitric Oxide Synthase: The Calmodulin and Output State Perspective

por Astashkin, Andrei V., Chen, Li, Zhou, Xixi, Li, Huiying, Poulos, Thomas L., Liu, Ke Jian, Guillemette, J. Guy, Feng, Changjian
Publicado 2014

Predicting the environmental fates of emerging contaminants: Synergistic effects in ozone reactions of nitrogen-containing alkenes

por Wang, Xinke, Wang, Weihong, Wingen, Lisa M., Perraud, Véronique, Ezell, Michael J., Gable, Jessica, Poulos, Thomas L., Finlayson-Pitts, Barbara J.
Publicado 2023

Potent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma

por Huang, He, Li, Huiying, Yang, Sun, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Meyskens, Frank L., Poulos, Thomas L., Silverman, Richard B.
Publicado 2014

The Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme–Inhibitor Interactions in Nitric Oxide Synthases

por Li, Huiying, Jamal, Joumana, Delker, Silvia, Plaza, Carla, Ji, Haitao, Jing, Qing, Huang, He, Kang, Soosung, Silverman, Richard B., Poulos, Thomas L.
Publicado 2014

Engineered ascorbate peroxidase as a genetically-encoded reporter for electron microscopy

por Martell, Jeffrey D., Deerinck, Thomas J., Sancak, Yasemin, Poulos, Thomas L., Mootha, Vamsi K., Sosinsky, Gina E., Ellisman, Mark H., Ting, Alice Y.
Publicado 2012

Structure-Based Design of Bacterial Nitric Oxide Synthase Inhibitors

por Holden, Jeffrey K., Kang, Soosung, Hollingsworth, Scott A., Li, Huiying, Lim, Nathan, Chen, Steven, Huang, He, Xue, Fengtian, Tang, Wei, Silverman, Richard B., Poulos, Thomas L.
Publicado 2014