Dna2 nuclease-helicase structure, mechanism and regulation by Rpa

por Zhou, Chun, Pourmal, Sergei, Pavletich, Nikola P
Publicado 2015

Dengue Virus Ensures Its Fusion in Late Endosomes Using Compartment-Specific Lipids

por Zaitseva, Elena, Yang, Sung-Tae, Melikov, Kamran, Pourmal, Sergei, Chernomordik, Leonid V.
Publicado 2010

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

por Remesh, Soumya G., Merz, Gregory E., Brilot, Axel F., Chio, Un Seng, Rizo, Alexandrea N., Pospiech, Thomas H., Lui, Irene, Laurie, Mathew T., Glasgow, Jeff, Le, Chau Q., Zhang, Yun, Diwanji, Devan, Hernandez, Evelyn, Lopez, Jocelyne, Pawar, Komal Ishwar, Pourmal, Sergei, Smith, Amber M., Zhou, Fengbo, DeRisi, Joseph, Kortemme, Tanja, Rosenberg, Oren S., Glasgow, Anum, Leung, Kevin K., Wells, James A., Verba, Kliment A.
Publicado 2022

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

por Remesh, Soumya G., Merz, Gregory E., Brilot, Axel F., Chio, Un Seng, Rizo, Alexandrea N., Pospiech, Thomas H., Lui, Irene, Laurie, Mathew T., Glasgow, Jeff, Le, Chau Q., Zhang, Yun, Diwanji, Devan, Hernandez, Evelyn, Lopez, Jocelyne, Mehmood, Hevatib, Pawar, Komal Ishwar, Pourmal, Sergei, Smith, Amber M., Zhou, Fengbo, DeRisi, Joseph, Kortemme, Tanja, Rosenberg, Oren S., Glasgow, Anum, Leung, Kevin K., Wells, James A., Verba, Kliment A.
Publicado 2023

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

por Schoof, Michael, Faust, Bryan, Saunders, Reuben A., Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B., Puchades, Cristina, Azumaya, Caleigh M., Kratochvil, Huong T., Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C., Chio, Cynthia M., Merz, Gregory E., Thompson, Michael C., Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A., Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R., Leon, Kristoffer, White, Kris M., Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M., Rizo, Alexandrea N., Moss, Frank, Brilot, Axel F., Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W., Nock, Silke, Liu, Yuwei, Krogan, Nevan J., Ralston, Corie Y., Swaney, Danielle L., García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish
Publicado 2020

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

por Schoof, Michael, Faust, Bryan, Saunders, Reuben A., Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B., Puchades, Cristina, Azumaya, Caleigh M., Kratochvil, Huong T., Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C., Chio, Cynthia M., Merz, Gregory E., Thompson, Michael C., Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A., Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R., Leon, Kristoffer, White, Kris M., Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M., Rizo, Alexandrea N., Moss, Frank, Brilot, Axel F., Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W., Nock, Silke, Liu, Yuwei, Krogan, Nevan J., Ralston, Corie Y., Swaney, Danielle L., García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish
Publicado 2020

Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance

por Mavor, David, Barlow, Kyle A., Asarnow, Daniel, Birman, Yuliya, Britain, Derek, Chen, Weilin, Green, Evan M., Kenner, Lillian R., Mensa, Bruk, Morinishi, Leanna S., Nelson, Charlotte A., Poss, Erin M., Suresh, Pooja, Tian, Ruilin, Arhar, Taylor, Ary, Beatrice E., Bauer, David P., Bergman, Ian D., Brunetti, Rachel M., Chio, Cynthia M., Dai, Shizhong A., Dickinson, Miles S., Elledge, Susanna K., Helsell, Cole V. M., Hendel, Nathan L., Kang, Emily, Kern, Nadja, Khoroshkin, Matvei S., Kirkemo, Lisa L., Lewis, Greyson R., Lou, Kevin, Marin, Wesley M., Maxwell, Alison M., McTigue, Peter F., Myers-Turnbull, Douglas, Nagy, Tamas L., Natale, Andrew M., Oltion, Keely, Pourmal, Sergei, Reder, Gabriel K., Rettko, Nicholas J., Rohweder, Peter J., Schwarz, Daniel M. C, Tan, Sophia K., Thomas, Paul V., Tibble, Ryan W., Town, Jason P., Tsai, Mary K., Ugur, Fatima S., Wassarman, Douglas R., Wolff, Alexander M., Wu, Taia S., Bogdanoff, Derek, Li, Jennifer, Thorn, Kurt S., O'Conchúir, Shane, Swaney, Danielle L., Chow, Eric D., Madhani, Hiten D., Redding, Sy, Bolon, Daniel N., Kortemme, Tanja, DeRisi, Joseph L., Kampmann, Martin, Fraser, James S.
Publicado 2018

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

por Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Publicado 2021

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

por Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Publicado 2021

Rapid deployment of SARS-CoV-2 testing: The CLIAHUB

por Crawford, Emily D., Acosta, Irene, Ahyong, Vida, Anderson, Erika C., Arevalo, Shaun, Asarnow, Daniel, Axelrod, Shannon, Ayscue, Patrick, Azimi, Camillia S., Azumaya, Caleigh M., Bachl, Stefanie, Bachmutsky, Iris, Bhaduri, Aparna, Brown, Jeremy Bancroft, Batson, Joshua, Behnert, Astrid, Boileau, Ryan M., Bollam, Saumya R., Bonny, Alain R., Booth, David, Borja, Michael Jerico B., Brown, David, Buie, Bryan, Burnett, Cassandra E., Byrnes, Lauren E., Cabral, Katelyn A., Cabrera, Joana P., Caldera, Saharai, Canales, Gabriela, Castañeda, Gloria R., Chan, Agnes Protacio, Chang, Christopher R., Charles-Orszag, Arthur, Cheung, Carly, Chio, Unseng, Chow, Eric D., Citron, Y. Rose, Cohen, Allison, Cohn, Lillian B., Chiu, Charles, Cole, Mitchel A., Conrad, Daniel N., Constantino, Angela, Cote, Andrew, Crayton-Hall, Tre’Jon, Darmanis, Spyros, Detweiler, Angela M., Dial, Rebekah L., Dong, Shen, Duarte, Elias M., Dynerman, David, Egger, Rebecca, Fanton, Alison, Frumm, Stacey M., Fu, Becky Xu Hua, Garcia, Valentina E., Garcia, Julie, Gladkova, Christina, Goldman, Miriam, Gomez-Sjoberg, Rafael, Gordon, M. Grace, Grove, James C. R., Gupta, Shweta, Haddjeri-Hopkins, Alexis, Hadley, Pierce, Haliburton, John, Hao, Samantha L., Hartoularos, George, Herrera, Nadia, Hilberg, Melissa, Ho, Kit Ying E., Hoppe, Nicholas, Hosseinzadeh, Shayan, Howard, Conor J., Hussmann, Jeffrey A., Hwang, Elizabeth, Ingebrigtsen, Danielle, Jackson, Julia R., Jowhar, Ziad M., Kain, Danielle, Kim, James Y. S., Kistler, Amy, Kreutzfeld, Oriana, Kulsuptrakul, Jessie, Kung, Andrew F., Langelier, Charles, Laurie, Matthew T., Lee, Lena, Leng, Kun, Leon, Kristoffer E., Leonetti, Manuel D., Levan, Sophia R., Li, Sam, Li, Aileen W., Liu, Jamin, Lubin, Heidi S., Lyden, Amy, Mann, Jennifer, Mann, Sabrina, Margulis, Gorica, Marquez, Diana M., Marsh, Bryan P., Martyn, Calla, McCarthy, Elizabeth E., McGeever, Aaron, Merriman, Alexander F., Meyer, Lauren K., Miller, Steve, Moore, Megan K., Mowery, Cody T., Mukhtar, Tanzila, Mwakibete, Lusajo L., Narez, Noelle, Neff, Norma F., Osso, Lindsay A., Oviedo, Diter, Peng, Suping, Phelps, Maira, Phong, Kiet, Picard, Peter, Pieper, Lindsey M., Pincha, Neha, Pisco, Angela Oliveira, Pogson, Angela, Pourmal, Sergei, Puccinelli, Robert R., Puschnik, Andreas S., Rackaityte, Elze, Raghavan, Preethi, Raghavan, Madhura, Reese, James, Replogle, Joseph M., Retallack, Hanna, Reyes, Helen, Rose, Donald, Rosenberg, Marci F., Sanchez-Guerrero, Estella, Sattler, Sydney M., Savy, Laura, See, Stephanie K., Sellers, Kristin K., Serpa, Paula Hayakawa, Sheehy, Maureen, Sheu, Jonathan, Silas, Sukrit, Streithorst, Jessica A., Strickland, Jack, Stryke, Doug, Sunshine, Sara, Suslow, Peter, Sutanto, Renaldo, Tamura, Serena, Tan, Michelle, Tan, Jiongyi, Tang, Alice, Tato, Cristina M., Taylor, Jack C., Tenvooren, Iliana, Thompson, Erin M., Thornborrow, Edward C., Tse, Eric, Tung, Tony, Turner, Marc L., Turner, Victoria S., Turnham, Rigney E., Turocy, Mary J., Vaidyanathan, Trisha V., Vainchtein, Ilia D., Vanaerschot, Manu, Vazquez, Sara E., Wandler, Anica M., Wapniarski, Anne, Webber, James T., Weinberg, Zara Y., Westbrook, Alexandra, Wong, Allison W., Wong, Emily, Worthington, Gajus, Xie, Fang, Xu, Albert, Yamamoto, Terrina, Yang, Ying, Yarza, Fauna, Zaltsman, Yefim, Zheng, Tina, DeRisi, Joseph L.
Publicado 2020

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

por Gordon, David E., Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V., Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S., Obernier, Kirsten, Guo, Jeffrey Z., Batra, Jyoti, Kaake, Robyn M., Weckstein, Andrew R., Owens, Tristan W., Gupta, Meghna, Pourmal, Sergei, Titus, Erron W., Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O’Meara, Matthew J., Tummino, Tia A., Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L., Fabius, Jacqueline M., Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M., Naing, Zun Zar Chi, Pulido, Ernst H., Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A., Azumaya, Caleigh M., Billesbølle, Christian, Brilot, Axel F., Campbell, Melody G., Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T., Liu, Yanxin, Merz, Gregory E., Moritz, Michelle, Nguyen, Henry C., Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Sun, Ming, Young, Iris D., Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R., Chen, Jen, Chio, Cynthia M., Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L., Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E., Melo, Arthur A., Moss, Frank R., Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K., Pospiech, Thomas H., Safari, Maliheh, Sangwan, Smriti, Schaefer, Kaitlin, Thomas, Paul V., Thwin, Aye C., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Whitis, Natalie, Yu, Zanlin, Zhang, Kaihua, Zhang, Yang, Zhou, Fengbo, Saltzberg, Daniel, Hodder, Anthony J., Shun-Shion, Amber S., Williams, Daniel M., White, Kris M., Rosales, Romel, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Patel, Arvind H., Rihn, Suzannah, Khalid, Mir M., Vallejo-Gracia, Albert, Fozouni, Parinaz, Simoneau, Camille R., Roth, Theodore L., Wu, David, Karim, Mohd Anisul, Ghoussaini, Maya, Dunham, Ian, Berardi, Francesco, Weigang, Sebastian, Chazal, Maxime, Park, Jisoo, Logue, James, McGrath, Marisa, Weston, Stuart, Haupt, Robert, Hastie, C. James, Elliott, Matthew, Brown, Fiona, Burness, Kerry A., Reid, Elaine, Dorward, Mark, Johnson, Clare, Wilkinson, Stuart G., Geyer, Anna, Giesel, Daniel M., Baillie, Carla, Raggett, Samantha, Leech, Hannah, Toth, Rachel, Goodman, Nicola, Keough, Kathleen C., Lind, Abigail L., Klesh, Reyna J., Hemphill, Kafi R., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Maures, Travis, Pollard, Katherine S., Sali, Andrej, Agard, David A., Cheng, Yifan, Fraser, James S., Frost, Adam, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M., Alessi, Dario R., Davies, Paul, Frieman, Matthew B., Ideker, Trey, Abate, Carmen, Jouvenet, Nolwenn, Kochs, Georg, Shoichet, Brian, Ott, Melanie, Palmarini, Massimo, Shokat, Kevan M., García-Sastre, Adolfo, Rassen, Jeremy A., Grosse, Robert, Rosenberg, Oren S., Verba, Kliment A., Basler, Christopher F., Vignuzzi, Marco, Peden, Andrew A., Beltrao, Pedro, Krogan, Nevan J.
Publicado 2020