All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells

por Gamper, Christopher J., Powell, Jonathan D.
Publicado 2012

Sugar, fat, and protein: new insights into what T cells crave

por Delgoffe, Greg M., Powell, Jonathan D.
Publicado 2015

Identification of the Molecular Mechanism by which TLR Ligation and IFN-γ Synergize to Induce Mig

por Powell, Jonathan D., Boodoo, Sada, Horton, Maureen R.
Publicado 2004

A2aR antagonists: Next generation checkpoint blockade for cancer immunotherapy

por Leone, Robert D., Lo, Ying-Chun, Powell, Jonathan D.
Publicado 2015

Egr3 Induces a Th17 Response by Promoting the Development of γδ T Cells

por Parkinson, Rose M., Collins, Samuel L., Horton, Maureen R., Powell, Jonathan D.
Publicado 2014

Manipulation of Metabolic Pathways and Its Consequences for Anti-Tumor Immunity: A Clinical Perspective

por Yang, Huang-Yu, Wu, Chao-Yi, Powell, Jonathan D., Lu, Kun-Lin
Publicado 2020

Cellular Size as a Means of Tracking mTOR Activity and Cell Fate of CD4+ T Cells upon Antigen Recognition

por Pollizzi, Kristen N., Waickman, Adam T., Patel, Chirag H., Sun, Im Hong, Powell, Jonathan D.
Publicado 2015

Pulmonary Vaccination as a Novel Treatment for Lung Fibrosis

por Collins, Samuel L., Chan-Li, Yee, Hallowell, Robert W., Powell, Jonathan D., Horton, Maureen R.
Publicado 2012

The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8(+) T cells in the tumor microenvironment

por Williams, Jason B., Horton, Brendan L., Zheng, Yan, Duan, Yukan, Powell, Jonathan D., Gajewski, Thomas F.
Publicado 2017

Regulation of CD4(+) and CD8(+) Effector Responses by Sprouty-1

por Collins, Sam, Waickman, Adam, Basson, Albert, Kupfer, Abraham, Licht, Jonathan D., Horton, Maureen R., Powell, Jonathan D.
Publicado 2012

Anti-oxidant inhibition of hyaluronan fragment-induced inflammatory gene expression

por Eberlein, Michael, Scheibner, Kara A, Black, Katharine E, Collins, Samuel L, Chan-Li, Yee, Powell, Jonathan D, Horton, Maureen R
Publicado 2008

Inhibition of glutamine metabolism accelerates resolution of acute lung injury

por Vigeland, Christine L., Beggs, Henry S., Collins, Samuel L., Chan‐Li, Yee, Powell, Jonathan D., Doerschuk, Claire M., Horton, Maureen R.
Publicado 2019

Targeting Metabolism as a Platform for Inducing Allograft Tolerance in the Absence of Long-Term Immunosuppression

por Cheng, Chih-Hsien, Lee, Chen-Fang, Oh, Byoung Chol, Furtmüller, Georg J., Patel, Chirag H., Brandacher, Gerald, Powell, Jonathan D.
Publicado 2020

Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells

por Vigeland, Christine L., Collins, Samuel L., Chan-Li, Yee, Hughes, Andrew H., Oh, Min-Hee, Powell, Jonathan D., Horton, Maureen R.
Publicado 2016

Hyaluronan fragments induce IFNβ via a novel TLR4-TRIF-TBK1-IRF3-dependent pathway

por Black, Katharine E, Collins, Samuel L, Hagan, Robert S, Hamblin, Mark J, Chan-Li, Yee, Hallowell, Robert W, Powell, Jonathan D, Horton, Maureen R
Publicado 2013

GOT1 regulates CD8(+) effector and memory T cell generation

por Xu, Wei, Patel, Chirag H., Zhao, Liang, Sun, Im-Hong, Oh, Min-Hee, Sun, Im-Meng, Helms, Rachel S., Wen, Jiayu, Powell, Jonathan D.
Publicado 2023

The mammalian Target of Rapamycin (mTOR) regulates T helper cell differentiation through the selective activation of mTORC1 and mTORC2 signaling

por Delgoffe, Greg M., Pollizzi, Kristen N., Waickman, Adam T., Heikamp, Emily, Meyers, David J., Horton, Maureen R., Xiao, Bo, Worley, Paul F., Powell, Jonathan D.
Publicado 2011

Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis

por Parveen, Sadiya, Shen, Jessica, Lun, Shichun, Zhao, Liang, Koleske, Benjamin, Leone, Robert D., Rais, Rana, Powell, Jonathan D., Murphy, John R., Slusher, Barbara S., Bishai, William R.
Publicado 2023

Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis

por Parveen, Sadiya, Shen, Jessica, Lun, Shichun, Zhao, Liang, Alt, Jesse, Koleske, Benjamin, Leone, Robert D., Rais, Rana, Powell, Jonathan D., Murphy, John R., Slusher, Barbara S., Bishai, William R.
Publicado 2023

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8 T cell differentiation

por Pollizzi, Kristen N., Sun, Im-Hong, Patel, Chirag H., Lo, Ying-Chun, Oh, Min-Hee, Waickman, Adam T., Tam, Ada J., Blosser, Richard L., Wen, Jiayu, Delgoffe, Greg M., Powell, Jonathan D.
Publicado 2016